2][3] BCMA signaling is critical for survival and proliferation of long-lived plasma cells. 4Impaired immune reconstitution, cytopenia, B-cell aplasia, hypogammaglobinemia (HGG) can compound preexisting MM-induced immunosuppression. 5In addition, bsAb redirect activate regulatory T cells, thus theoretically increasing the risk infections. 6Here, we describe infectious complications observed across different BCMA-directed T-cell therapies (bsAb CAR-T) in relapsed/refractory MM clinical trials...

Background: Emerging health technologies are increasingly being used in care for communication, data collection, patient monitoring, education, and facilitating adherence to chronic disease management. However, there is a lack of studies on differences the preference using information exchange between patients with nonchronic diseases factors affecting these differences. Objective: The purpose this paper understand preferences use technology among nationally representative sample adults...

Current Endocrine Society guidelines recommend that transgender women taking spironolactone have their potassium levels checked every 3 months for the first year after initiating therapy and annually thereafter to monitor hyperkalemia.The goal of this study was assess need such frequent monitoring investigate whether age plays a role in abnormalities transgender, gender diverse, nonbinary (TGDNB) individuals spironolactone.Using EPIC-Clarity, retrospective healthy, adult with gender-identity...

Examine the relationship between food and housing insecurities, quality of care life in adults with diabetes using a nationally representative data source.

Abstract Background Disparities in health care utilization and outcomes for racial ethnic minorities with arthritis are well-established. However, there is a paucity of research on differences healthcare expenditures if this relationship has changed over time. Our objectives were to: 1) examine trends annual adults by race ethnicity, 2) determine independent other factors such as access functional disability. Methods We used the Medical Expenditures Panel Survey (2008–2016) to within between...

One way to provide performance feedback hospitalists is through the use of dashboards, which deliver data based on agreed-upon standards. Despite growing trend quality metrics, there remain limited means, frequency and content that should be provided frontline hospitalists.The objective our research report experience with a comprehensive system for hospitalists, as well change in metrics after implementation.This improvement project was conducted at tertiary academic medical centre among...

This paper aimed to determine whether there was a connection between patient's perception of communication with their doctors in the visit and use online health information exchange using nationally representative survey. We used data from Health Information National Trends survey pooled HINTS4 Cycle 4 assessed outcomes logistic regression modeling composite scores as continuous variable. weighted participants create population-level estimates. adjusted for age, gender, race, census region....

The impact of achieving hemodialysis laboratory and hemodynamic quality metrics on patient-reported outcomes (PROs) is unknown.To determine if meeting dialysis care measures associated with improved PROs.In this cross-sectional study, we measured the relationship between patients' Patient Reported Outcome Measurement Information System (PROMIS) scores commonly used measures.PROMIS surveys were administered to 92 patients. mean ± SD demonstrated higher fatigue (55.0 9.8) lower physical...

Objectives: Diabetes results in $327 billion medical expenditures annually, while obesity, a risk factor for type 2 diabetes, leads to more than $147 expendi­ture annually. The aims of this study were: 1) evaluate racial/ethnic trends obesity and expenditures; 2) assess incremental among nationally representative sample women with diabetes.Methods: Nine years data (2008–2016) from the Medical Expenditure Panel Survey Full Year Consolidated File (unweighted = 11,755; weighted 10,685,090) were...

Purpose To evaluate patient access, provider productivity, and satisfaction during a 24-month redesign process of an academic medical center, which requires balance between clinical educational missions.Methods A series activities were conducted to optimize primary care across 17 attending physicians, 6 Advanced Practice Providers (APPs), 39 residents. Patient access was defined as the next available appointment for either existing/established patients or new patients. Productivity measured...

Background: Given the high cost of inpatient stays, hospital systems are investigating ways to decrease lengths stay while ensuring high-quality care. The goal this study was determine if patients in teaching teams (hospitalist with residents and interns) had a higher length after adjusting for relevant confounders compared hospitalist-only (staffed only by attending physicians).Methods: Using retrospective design, we investigated differences 17,577 encounters over 2-year period. Length...

The global burden of hypertension is growing, particularly in low- and middle-income countries. This study aimed to investigate differences the relationship between social capital regions Sub-Saharan Africa (West vs. South Africa) within (rural urban residence each country).Data for 9,800 adults were analyzed from Study on Global Ageing Adult Health (SAGE) 2007-2010 Ghana African emerging economy) (South established economy). Outcomes self-reported measured hypertension. primary independent...

As the global burden of diabetes persists, research is needed to understand role wealth and correlates across regions world. The purpose this study examine prevalence 6 low- middle- income countries while also accounting for independent by country.

Abstract Introduction Racial and ethnic inequity in pain management have been well documented peer‐reviewed literature. A recent publication suggested opioid prescription rates for Black White patients among 310 large racially diverse health systems, including Froedtert & the Medical College of Wisconsin (F&MCW). This prompted F&MCW to further investigate its own data. Pharmacists led similar investigations evaluate racial inequities care, are well‐positioned assess prescribing....

Purpose The purpose of this paper is to examine the influence insurance coverage changes over time for patients with diabetes on expenditures and access care before after Affordable Care Act (ACA). Design/methodology/approach Medical Expenditure Panel Survey (MEPS) from 2002–2017 was used. Access included having a usual source care, delay in or obtaining prescription medicine. Expenditures inpatient, outpatient, office-based, emergency costs. Panels were broken into four categories:...