- Systemic Sclerosis and Related Diseases
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatologic Treatments and Research
- Autoimmune Bullous Skin Diseases
- Uterine Myomas and Treatments
- Olfactory and Sensory Function Studies
- Menopause: Health Impacts and Treatments
- Glioma Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Cancer Immunotherapy and Biomarkers
- Menstrual Health and Disorders
- Meningioma and schwannoma management
- Chronic Lymphocytic Leukemia Research
- Pituitary Gland Disorders and Treatments
- Endometrial and Cervical Cancer Treatments
- Pelvic floor disorders treatments
- Advanced Breast Cancer Therapies
- Tracheal and airway disorders
- Skin Protection and Aging
- melanin and skin pigmentation
- Respiratory Support and Mechanisms
- PI3K/AKT/mTOR signaling in cancer
- Head and Neck Cancer Studies
Xiangya Hospital Central South University
2019-2021
Central South University
2019-2021
Weatherford College
2020
Chengdu University of Traditional Chinese Medicine
2019
Houston Methodist
2019
Chongqing Medical University
2016
The First People's Hospital of Shunde
2001
Histone H3K27 demethylase, JMJD3 plays a critical role in gene expression and T-cell differentiation. However, the mechanisms of T cell trafficking remain poorly understood. Here we show that deficiency CD4+ cells resulted an accumulation thymus, reduction number secondary lymphoid organs. We identified PDLIM4 as significantly down-regulated target JMJD3-deficient by profiling ChIP-seq analyses. further showed functioned adaptor protein to interact with S1P1 filamentous actin (F-actin), thus...
Background: Adenomyosis is benign gynecologic condition with complex etiologies. Common symptoms associated adenomyosis (AM) include menorrhagia, dysmenorrhea, chronic pelvic pain, metrorrhagia, and dyspareunia. Although Chinese herbal medicine (CHM) has often been utilized for managing AM in clinical practice China, evidence regarding its efficacy lacking. This systematic review protocol aims to describe a assess the effectiveness safety of CHM combined Levonorgestrel-releasing intrauterine...
Abstract Background: Premature ovarian insufficiency (POI) is a difficult-to-treat gynecological disorder with complex etiologies. Although acupuncture has gained increased popularity for the management of POI, evidence regarding its efficacy lacking. This systematic review protocol aims to describe meta-analysis assess effectiveness and safety patients POI. Methods: The following 10 databases will be searched from publishment July 2019: PubMed, Embase, Web Science, Cochrane Central Register...
Abstract In 2018 AAI annual meeting, we presented our discover that JMJD3 was bound to the promoter and gene body regions of Pdlim4 it regulated PDLIM4 expression by interacting with zinc finger transcription factor KLF2. as an filamentous actin (F-actin) binding protein, involved in T cell trafficking. However, role mechanisms trafficking remain unclear. this abstract, showed adaptor protein connecting S1P1 a key regulator Our studies indicated interacted N terminal PDZ domain. The PLDIM4 C...