- Bacteriophages and microbial interactions
- Cancer-related Molecular Pathways
- Genomics and Phylogenetic Studies
- Probiotics and Fermented Foods
- Banana Cultivation and Research
- Gut microbiota and health
- FinTech, Crowdfunding, Digital Finance
- Computational Drug Discovery Methods
- Microtubule and mitosis dynamics
- Nitric Oxide and Endothelin Effects
- Cancer Mechanisms and Therapy
- Pomegranate: compositions and health benefits
- Tannin, Tannase and Anticancer Activities
- Vibrio bacteria research studies
- Synthesis and biological activity
- Moringa oleifera research and applications
- Chromium effects and bioremediation
- Circular RNAs in diseases
- Bacterial Genetics and Biotechnology
- Antibiotic Resistance in Bacteria
- Viral gastroenteritis research and epidemiology
- Microfinance and Financial Inclusion
- Listeria monocytogenes in Food Safety
- Escherichia coli research studies
- Odor and Emission Control Technologies
Amrita Vishwa Vidyapeetham
2017-2024
Jawaharlal Nehru Technological University, Hyderabad
2007-2023
Naval Science & Technological Laboratory
2012
Institut des Sciences Moléculaires
2010
Translational Research Institute
2010
Institute of Bioinformatics
2007-2008
QSAR analysis on a set of synthesized chalcone derivatives tested for growth inhibitory activity against Bacillus pumilis was performed by using multiple regression procedure.The contributions these compounds were determined from equation and the validation procedures to analyze predictive ability model described.The generated 25 molecule training 7 47 independent variables revealed that an increase in ADME Weight, Kappa2 index decrease HOMO energy as favorable descriptors inhibition.
Recent literature has suggested a novel symbiotic relationship between bacteriophage and metazoan host that provides antimicrobial defense protecting mucosal surface by binding to matrix mucin glycoproteins. Here, we isolated studied different bacteriophages specifically interact with human extracellular molecules such as fibronectin, gelatin, heparin demonstrated their potency for protection against microbial infections. We showed subpopulations of work clinical isolates Escherichia coli...
Environmental enteropathy (EE), a chronic small intestine disease characterized by gut inflammation, is widely prevalent in low-income countries and hypothesized to be caused continuous exposure fecal contamination. Targeted nutritional interventions using potential probiotic strains from fermented foods can an effective strategy inhibit enteric pathogens prevent inflammation.We isolated rice water lemon pickle investigated their cell surface properties, antagonistic adhesion HT-29 cells,...
We report the draft genome sequence of Escherichia coli ASBT-1, a representative E. type 155 (ST155), obtained from India. Considering known wide variety pathogenic and antibiotic resistance potentials, this strain should be great interest for detailed comparative genomic analysis.
Robust control of pathogens in sewage facilitates safe reuse wastewater rich valuable nutrients for potential valorization through biological means. Aspergillus niger is widely reported bioremediation but studies on enteric are very sparse. So, this study aimed at exploring the antibacterial and nematicidal activity A. culture filtrate (ACF). Antibacterial ACF (Klebsiella pneumoniae, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella enterica, Shigella dysenteriae, Escherichia coli,...
In the present study, antioxidant activities of rhizome Musa acuminata were investigated. Free radical scavenging assay (DPPH) and reducing power ethanolic extract banana resulted in potential activities. A relatively high percentage activity by DPPH (81.41% at 200 μg/ml) which was comparable to that standard, ascorbic acid 100 μg/ml observed. With gallic as standard showed a low reductive potential, however, when tested for cytotoxicity highest concentration dose (256 μg/ml), maximum rate...
Database of Databases (DoD) is a collection molecular biology databases extracted from Nucleic Acids Research, 2005 issue. DoD constructed using javascript and html code. The 14 categories 719 are provided with search option, keyword help database description linked to respective pages. Keyword lists the strings used perform an individual against categorized databases. provides brief information about link full-text article main web page. available online can be accessed at...
CDK2 (Cyclin Dependent Kinase 2) acts as a potential therapeutic target in cancer and several efforts have been made to find more specific, potent selective ATP competitive inhibitors. In this paper, we report virtual screening approach that resulted 54,558 Lipinski compliant hits from ZINC database based on the features exhibited by four compounds our previous study. Docking scoring of all using GOLD (Genetic Optimisation for Ligand Docking) software, evaluate affinity binding towards...
We report the draft genome sequence of a putative probiotic strain, Lactobacillus fermentum ASBT-2, isolated from domestic sewage in Kerala, India. The strain showed properties (tolerance to low pH and bile salts, binding host matrix) reduced coliform count by 90% biofilter used treat wastewater.
Abstract Enteric infection by faecal contamination of drinking water is a major concern in developing nations contributing to the huge burden malnutrition and infant mortality. We have developed holistic approach, named as gut gutter treat wastewater treatment, screening potential probiotic strains from staple food sources. The could be potentially used for competing out enteric pathogens different applications such treatment. focused on two isolated rice (RS) lemon pickle (T1), identified...
Technology has transformed the way of banking and brought a new dimension in industry. Internet gained popularity due to its convenience flexibility. This concept technology are relatively rural consumers, with most people adopting it past year. Among various services offered by banks through internet banking, balance inquiries commonly used. Other like term loans, online fixed deposits, demand draft facilities not as widely used, possibly underdeveloped awareness these features. Consumers...
Arsenic contamination of soil and water is a major environmental issue. Bioremediation through plant growth-promoting bacteria viable, cost-effective, sustainable. Along with arsenic removal, it also improves productivity under stressful conditions. A crucial aspect such strategy the selection bacterial inoculum. The described study demonstrates that indigenous wastewater isolate, ASBT-KP1, could be promising candidate. Identified as