Obesity and excess weight are a pandemic phenomenon in the modern world. Childhood adolescent obesity often ends up adults. The costs of its consequences staggering for any society, crippling countries development. is also widespread Macedonia. Metabolic syndrome, dyslipidemia carbohydrate intolerance found significant numbers. Parents grandparents obese. Some children either dysmorphic, or slightly retarded. We have already described patients with Prader-Willi Bardet-Biedl syndrome WAGR...

BACKGROUND: In the past several decades, increasing frequency of overweight and obese children adolescents in world has become a public health problem. It contributed significantly to already high tide diabetes, cardiovascular cerebrovascular diseases.AIM: To investigate insulin resistance evaluate metabolic profile resistant non-insulin adolescents.SUBJECTS AND METHODS: The study included 96 (45 boys, 51 girls) aged 4-17 years old (10.50 ± 2.87 years). Only participants with Body Mass Index...

The name Marivivens marinum, published as sp. nov. by Kang et al. (Int J Syst Evol Microbiol 2025;75 : 006735) contravenes Rule 12 c(1) of the International Code Nomenclature Prokaryotes (ICNP). Albeit authors genus Park 2016 did not specify gender name, epithet donghaensis type species was given masculine gender, and so geojensis (Lee 2019) Qu 2022. Therefore, we here correct marinum to marinus corrig. We also give examples use present participles names, based on rules ICNP past usage in...

Myiasis is an infestation of the tissues livinghumans and other vertebrates by immature stages (larvae) Diptera. According to International Classification Diseases, myiasis belongs morbidity classification ICD-10-CM, with ICD code B87 (2025 edition). not mandatory report, through our experience, we aimed raise awareness this among medical practitioners public. We discuss seven cases diagnosed over five years (2019-2024) whose specimens was submitted Institute for Microbiology Parasitology,...

According to the Rules of International Code Nomenclature Prokaryotes (ICNP) and its appendices, names higher taxa are formed by addition appropriate suffix stem name type genus, word stems derived from Latin and/or Greek combined compound means an connecting vowel. The way ‘stem’ is used in ICNP differs meaning this term textbooks grammar. We therefore propose add a Note Rule 8, clarifying that when corresponds with part does not vary among forms noun oblique cases, i.e., cases other than...

Introduction: The major risk factor for acquiring an infection with Clostridioides difficile (CDI) is a long-term antibiotic treatment. Contrarily, the treatment of severe CDI cases involves application antibiotics like vancomycin or metronidazole. Our aim was to investigate percentage resistance eight (vancomycin, metronidazole, tetracycline, clindamycin, erythromycin, imipenem, ciprofloxacin and moxifloxacin) among isolates, indirectly evaluating risks therapeutic failure. Materials...

Abstract A 16‐year‐old girl with a history of nontraumatic swelling both forearms, osteochondromas the knees, heterotopic ossification neck and back, severe malformations all digits hypoplastic or absent nails, alopecia partialis scalp, moderate cognitive impairment was seen for diagnostic evaluation. Whole exome sequencing identified an activating mutation ACVR1 (c.983G > A; p.Gly328Glu) which confirmed suspected FOP variant. The delayed diagnosis variant in this patient could have been...

Aim: The aim of our study was to determine the most common bacteria isolated from wound samples and tо compare frequency resistant over a 3-year period. Material methods: During three years period (2017-2019) total 11 863 (wound swabs, punctuates, exudates, tissue, etc.) were obtained hospitalized patients in University Clinics ,,Mother Theresa” campus, City hospital ,,8th September” Clinic for surgical diseases ,,St. Naum Ohridski” Skopje. All processed at Institute Microbiology...

Abstract Background : Campylobacter infections are typically self-limited, but in cases with severe enteritis, immuno-compromised system and bacteremia, an appropriate antimicrobial treatment is demanding. Our study aim was to determine the isolation rate of among patients acute enteritis capital North Macedonia its susceptibility. Material methods A total number 3820 clinically diagnosed as were included study. Stool samples collected isolated identified by classical microbiological...

Acquired lymphangiectasia of the vulva is very uncommon. Owing to non-specific papillomatous manifestation and vast array possible differential diagnoses, lymphangioma circumscriptum (LC) still presents a diagnostic challenge. In this report, we present rare form acquired vulvar LC in 71-year-old patient with longstanding history asymptomatic lesions over labia majora that had been previously treated as genital warts. On examination, multiple clustered translucent papules up 15mm diameter,...

Diabetic foot ulcers(DFUs) as one of the most common complications in patients with diabetes mellitus are usually chronic wounds.The reason for its chronicity infections and biofilm formation. We present a patient diabetic neuropathic ulcer on right foot. Microbiological swab showed isolates  bacteria fungi, Candida albicans,Enterococcus Acinetobacter which were tested formation microtiter plate assay. Biofilm mass was evaluated spectrophotometrically by measuring absorbence crystal...

BACKGROUND: Squamous cell carcinoma (SCC) of the lower lip is a relatively rare carcinoma, with incidence 1 to 2%, but it most common in oral cavity accounting for 25-30% all malignant tumours.
 AIM: This study aimed determine role neovascularisation process tumour progression.
 METHODS: We analysed surgical specimens obtained from 60 patients squamous lip. The examined group consisted 45 without metastasis and 15 regional lymph nodes. Histopathological slides were...

Abstract Background: Obesity is the most common chronic metabolic disease in children and adolescents. It has reached epidemic ranges a significant global problem. Objective : This study aimed to investigate possible disturbances adolescents with obesity severe obesity. Subjects methods: cross-sectional included 158 (82 boys, 76 girls) obese between ages of 0 17years (10.43 ± 3.11 years). The was defined according sex- age-specific growth charts proposed by Centers for Disease Control...

Background Diabetic nephropaty (DN) occurs in approximately 40% of patients with diabetes mellitus, and is the most common cause end-stage renal disease. The mechanisms DN are not very clear more recently, but renin-angiotensin system (RAS) plays an important role. It has been known that rennin-angiotensin blockers have a protective effect. present study was undertaken to evaluate effects candesartan on functional tests streptozotocin (STZ) induced rats. Methods DM by single intraperitoneal...

Healthcare-associated and community-acquired infections caused by Gram-negative bacteria are serious health concerns due to the rise of antibiotic resistance. Antimicrobial resistance (AMR) is a highly concerning issue in field medicine today, as it has significant impacts on morbidity, mortality, socio-economic factors. Blood samples from inpatients admitted at Clinical Microbiology Laboratory during study period January 2022 until December 2023 were included analysis. culture bottles for...