A5101422928- Esophageal Cancer Research and Treatment
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- dental development and anomalies
- Renal cell carcinoma treatment
- 14-3-3 protein interactions
- Organ and Tissue Transplantation Research
- Reconstructive Surgery and Microvascular Techniques
- Aluminum toxicity and tolerance in plants and animals
- Oral health in cancer treatment
- Retinoids in leukemia and cellular processes
- Brain Metastases and Treatment
- Facial Trauma and Fracture Management
- Urinary and Genital Oncology Studies
- Photodynamic Therapy Research Studies
- Glycosylation and Glycoproteins Research
- Occupational and environmental lung diseases
- Neuroblastoma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Immune Response and Inflammation
- Bone Metabolism and Diseases
- RNA Interference and Gene Delivery
- Mast cells and histamine
- Anatomy and Medical Technology
- Antioxidant Activity and Oxidative Stress
Chinese Academy of Medical Sciences & Peking Union Medical College
2003-2020
General Hospital of Shenyang Military Region
2014-2018
Air Force Medical University
2017
Southwest Hospital
2006
Peking University
1989-1995
Peking University Cancer Hospital
1989
Esophageal cancer incidence and mortality rates in Linxian, China are among the highest world. We examined risk factors for esophageal squamous cell carcinoma (ESCC), gastric cardia (GCC), noncardia (GNCC) a population-based, prospective study of 29,584 adults who participated Linxian General Population Trial. All participants completed baseline questionnaire that included questions on demographic characteristics, personal family history disease, lifestyle factors. After 15 years follow-up,...
Periodontitis is initiated and sustained by bacteria. However, the mechanism of bacteria induced periodontitis still unknown. We hypothesized that bacterial components can affect functions stem cells in periodontium. In this study, we comparatively investigated influence Lipopolysaccharide (LPS) on osteogenesis potential human periodontal ligament (PDLSCs) bone marrow mesenchymal (BMMSCs).Human PDLSCs BMMSCs were harvested mineralized nodule formation was assessed alizarin red S staining....
The longstanding goal of periodontal therapy is to regenerate tissues. Although platelet-rich plasma (PRP) has been gaining increasing popularity for use in the orofacial region, whether PRP useful regeneration still unknown. purpose this study was determine a mixture ligament stem cell (PDLSC) sheets and promoted bone regeneration, one most important measurement indices tissue regenerative capability vitro vivo. In study, we evaluated effects different doses on differentiation human PDLSCs....
Physiological primary teeth exfoliation is a normal phenomenon during development. However, retained can often be observed in the patients with cleidocranial dysplasia (CCD) caused by mutation of Runx2. The potential regulative mechanism still unknown. In present study, periodontal ligament stem cells (PDLSCs) were derived from different resorbed stages and permanent CCD patient. proliferative, osteogenic osteoclast-inductive capacities PDLSCs each group detected. We demonstrated here that...
With an enormous amount of research concerning kidney cancer being conducted, various treatments have been applied to its cure. However, high recurrence and metastasis rates continue pose a threat the survival patients with renal clear cell carcinoma (KIRC). Data from The Cancer Genome Atlas were downloaded, series analyses performed, including differential analysis, Cox weighted gene coexpression network least absolute shrinkage selection operator multivariate receiver operating...
自2006年开展癌症早诊早治项目以来，已筛查1027 140例高危个体，检出6866例患者，早诊率为77．9％，治疗率为80．4％。如何评价这一结果，受到广泛关注。按照循证医学的原则，癌症早诊早治评价有明确的标准和方法旧一，绩效评价的终点指标是死亡率下降，而卫生经济学评价，则要求详细计算癌症早诊早治的费用，以及相应的健康收益，分别以成本效果、成本效用和成本效益来表述，
Murine monoclonal antibody (MoAb) BB4.3, raised against the human gastric cancer cell line BGC823, was puriffied with Protein A-Sepharose CL-4B affinity chromatography and identified as IgG2a. It then conjugated a hematoporphyrin derivative (HPD) by using carbodiimide. The qualitative analysis of this conjugate showed that amount free HPD negligible there were no IgG aggregates among conjugates. retained both photochemical activity HPD. In vitro, phototoxic effect HPD-BB4.3 on target cells...
Abstract Esophageal cancer is one of the most common cancers worldwide and half all new cases occurred in China. Population-based endoscopic screening has been carried out some high-risk areas China since 2005, but previous evidence was based predominately on small-sample, single-center studies. We undertook a population-based, multi-center cohort study to estimate effectiveness program reducing incidence mortality esophageal high risks Methods This conducted six from 2005 2015. All...
In this article, the significance of radioimmunoimaging (RII) as a mornitoring means for gastric colorectal and lung cancer patients was reported. By using I - 131 or Tc 99m labeled C50 (antiCEA) 3H11 (anti human cancer), 86 positive lesions were identified in 50 patiens. 77 out (89.5%) true positive, 4 false by post surgecal pathology, biopsy CT scan. The other 5 remained to be unexplained needed further follow-up. our clinical practice, RII with antitumor McAbs suggested its unique value...