A5006635528- Health Systems, Economic Evaluations, Quality of Life
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Chronic Disease Management Strategies
- Primary Care and Health Outcomes
- Parkinson's Disease Mechanisms and Treatments
- Patient Satisfaction in Healthcare
- Health disparities and outcomes
- Shoulder Injury and Treatment
- Hip and Femur Fractures
- Clinical practice guidelines implementation
- Rheumatoid Arthritis Research and Therapies
- Healthcare Policy and Management
- Geriatric Care and Nursing Homes
- Amyotrophic Lateral Sclerosis Research
- Cerebral Palsy and Movement Disorders
- Hip disorders and treatments
- Musculoskeletal pain and rehabilitation
- Delphi Technique in Research
- Telemedicine and Telehealth Implementation
- Family and Disability Support Research
- Patient-Provider Communication in Healthcare
- Interprofessional Education and Collaboration
- Shoulder and Clavicle Injuries
- Schizophrenia research and treatment
University of Oxford
2016-2025
London School of Hygiene & Tropical Medicine
1992-2024
University of Kansas
2024
King's College London
2024
Institute of Health Services and Policy Research
2024
Oxford Health NHS Foundation Trust
1992-2023
Keele University
2001-2023
University of Washington
1997-2022
Seattle University
2022
National Institute for Health Research
2021
We have developed a 12-item questionnaire for patients having total knee replacement (TKR). made prospective study of 117 before operation and at follow-up six months later, asking them to complete the new form SF36. Some also filled in Stanford Health Assessment Questionnaire (HAQ). An orthopaedic surgeon completed American Knee Society (AKS) clinical score. The single score derived from had high internal consistency, its reproducibility, examined by test-retest reliability, was found be...
The Oxford hip and knee scores have been extensively used since they were first described in 1996 1998. During this time, modified for many different purposes. This paper describes how should be seeks to clarify areas of confusion.
to briefly outline the development and validation of Parkinson's Disease Questionnaire (PDQ-39) then provide evidence for use measure as either a profile health status scores or single index figure.the PDQ-39 was administered in two surveys: postal survey patients registered with local branches Society Great Britain (n = 405) attending neurology clinics treatment disease 146). Data from eight dimensions were factor-analysed. This produced factor on data both surveys.the new score-the summary...
We developed a 12-item questionnaire for completion by patients having total hip replacement (THR). A prospective study of 220 was undertaken before operation and at follow-up six months later. Each completed the new as well SF36, some Arthritis Impact Measurement Scales (AIMS). An orthopaedic surgeon assessed Charnley score. The single score derived from had high internal consistency. Reproducibility examined test-retest reliability found to be satisfactory. validity established obtaining...
We have developed a 12-item questionnaire for patients having total knee replacement (TKR). made prospective study of 117 before operation and at follow-up six months later, asking them to complete the new form SF36. Some also filled in Stanford Health Assessment Questionnaire (HAQ). An orthopaedic surgeon completed American Knee Society (AKS) clinical score. The single score derived from had high internal consistency, its reproducibility, examined by test-retest reliability, was found be...
<b><i>Objective:</i></b> To develop a patient-based measure of walking ability in MS. <b><i>Methods:</i></b> Twelve items describing the impact MS on (12-Item Walking Scale [MSWS-12]) were generated from 30 patient interviews, expert opinion, and literature review. Preliminary psychometric evaluation (data quality, scaling assumptions, acceptability, reliability, validity) was undertaken data by 602 people Society membership database. Further (including comprehensive validity assessment,...
Many clinicians remain unsure of the relevance measuring quality life to their clinical practice. In health economics measures have become standard means assessing results care interventions and, more controversially, prioritising funding; but they many other applications. This article--the first three on life--reviews instruments available and application in screening programmes, audit, research, trials. Using appropriate instrument is essential if outcome are be valid clinically meaningful.
We developed a 12-item questionnaire for completion by patients having shoulder operations other than stabilisation. A prospective study of 111 was undertaken before operation and at follow-up six months later. Each patient completed the new SF36 form. Some filled in Stanford Health Assessment Questionnaire (HAQ). An orthopaedic surgeon assessed Constant score. The single score derived from had high internal consistency. Reproducibility, examined test-retest reliability, found to be...
Using two restriction site polymorphisms within the structural gene coding for human type II collagen we have examined segregation of this in three pedigrees with dominantly inherited osteogenesis imperfecta (Sillence IA). We demonstrated that does not segregate clinical expression disease and cannot, therefore, contain mutation responsible these families.
<b>Objective</b> To assess the effect of home based telehealth interventions on use secondary healthcare and mortality. <b>Design</b> Pragmatic, multisite, cluster randomised trial comparing with usual care, using data from routine administrative datasets. General practice was unit randomisation. We allocated practices a minimisation algorithm, did analyses by intention to treat. <b>Setting </b>179 general in three areas England. <b>Participants </b>3230 people diabetes, chronic obstructive...
<h3>Objective</h3> To investigate if unemployment during an economic downturn is associated with mortality, even among men markers of better health (higher cognitive function scores and qualifications), to assess whether the associations vary by age at unemployment. <h3>Design</h3> Longitudinal register-based cohort study. <h3>Setting</h3> Study entry was in 1990 2001 when Sweden entering periods significant contraction. <h3>Participants</h3> A representative sample from general population...
Telehealth (TH) and telecare (TC) interventions are increasingly valued for supporting self-care in ageing populations; however, evaluation studies often report high rates of non-participation that not well understood. This paper reports from a qualitative study nested within large randomised controlled trial the UK: Whole System Demonstrator (WSD) project. It explores barriers to participation adoption TH TC perspective people who declined participate or withdrew trial. Qualitative...
Abstract The Parkinson's Disease Questionnaire (PDQ-39) is a disease specific measure of health status which covers eight dimensions ill-health, and contains 39 questions. development the questionnaire has been outlined in full elsewhere briefly this paper. Psychometric techniques are used here to derive single index figure from PDQ-39, transformed score range 0 (good health) 100 (poor health). A sub-set items then selected PDQ-39 create shorter form version, PDQ-8. Each item one most highly...
<h3>Abstract</h3> <b>Objective</b>: To assess the effect on time to diagnosis of recurrence and quality life transferring primary responsibility for follow up women with breast cancer in remission from hospital general practice. <b>Design</b>: Randomised controlled trial 18 month which received routine either or <b>Subjects setting</b>: 296 receiving regular care at district hospitals England. <b>Main outcome measures</b>: Time between first presentation symptoms confirmation recurrence;...
The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning although 'active ingredient' intervention that is effective difficult specify." A typical example specialist care on a stroke unit, involves wide range health professionals delivering variety treatments. Michelle Campbell and colleagues have argued there are "specific difficulties in defining, developing, documenting, reproducing...
The importance of general statistical principles study design and analysis to quality-of-life assessment in clinical trials is emphasized. Basic methods are reviewed briefly, with reference three examples. Careful use standard tools supplemented context-specific scales recommended. Problems weighting aggregation discussed; the simple schemes by sensitivity suggested. Some technical issues explored, including factorial question structure, components variance distinguish mean treatment...
<b>Objective</b> To examine the costs and cost effectiveness of telehealth in addition to standard support treatment, compared with treatment. <b>Design</b> Economic evaluation nested a pragmatic, cluster randomised controlled trial. <b>Setting</b> Community based intervention three local authority areas England. <b>Participants</b> 3230 people long term condition (heart failure, chronic obstructive pulmonary disease, or diabetes) were recruited into Whole Systems Demonstrator trial between...
BackgroundLate-stage isolated medial knee osteoarthritis can be treated with total replacement (TKR) or partial (PKR). There is high variation in treatment choice and little robust evidence to guide selection. The Total Partial Knee Arthroplasty Trial (TOPKAT) therefore aims assess the clinical effectiveness cost-effectiveness of TKR versus PKR patients compartment knee, this represents an analysis main endpoints at 5 years.MethodsOur multicentre, pragmatic randomised controlled trial was...