A5052601827- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neuroscience and Neuropharmacology Research
- Hemodynamic Monitoring and Therapy
- Caveolin-1 and cellular processes
- Anesthesia and Sedative Agents
- Inflammatory Biomarkers in Disease Prognosis
- Respiratory Support and Mechanisms
- Autophagy in Disease and Therapy
- Mesenchymal stem cell research
- Pediatric Pain Management Techniques
- Family and Patient Care in Intensive Care Units
- Ferroptosis and cancer prognosis
- Airway Management and Intubation Techniques
- Sleep and Wakefulness Research
- Occupational and environmental lung diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Pulmonary Hypertension Research and Treatments
- Neonatal Respiratory Health Research
- Sarcoidosis and Beryllium Toxicity Research
- Eicosanoids and Hypertension Pharmacology
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
The First Affiliated Hospital, Sun Yat-sen University
2022-2024
Sun Yat-sen University
2022-2024
Idiopathic pulmonary fibrosis (IPF) represents a severe and progressive manifestation of idiopathic interstitial pneumonia marked by an uncertain etiology along with unfavorable prognosis. Osteoglycin (OGN), belonging to the small leucine-rich proteoglycans family, assumes pivotal functions in both tissue formation damage response. However, roles potential mechanisms OGN context lung remain unexplored.
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive deadly fibrotic lung disease with high prevalence mortality worldwide. The therapeutic potential of mesenchymal stem cells (MSCs) in may be attributed to the strong paracrine, anti-inflammatory, anti-apoptosis immunoregulatory effects. However, mechanisms underlying effects MSCs IPF, especially terms alveolar type 2 (AT2) senescence, are not well understood. purpose this study was evaluate role NAD...
Introduction Sepsis-induced cardiomyopathy is a common complication of sepsis and associated with higher mortality. To date, effective diagnostic management strategies are still lacking. Recent studies suggest that ferroptosis plays critical role in sepsis-induced inhibitor Ferrostatin-1 (Fer-1) improved cardiac dysfunction survival lipopolysaccharide (LPS) induced endotoxemia. However, the effects Fer-1 early stages cecal ligation puncture (CLP) remains unclear. Our study aims to elucidate...
Opioid consumption for analgesia in burn patients is enormous. Non-opioid analgesics pain management may result opioid sparing, reducing opioid-related adverse reactions and drug tolerance or addiction.
There is still a lack of specific indicators to diagnose idiopathic pulmonary fibrosis (IPF). And the role immune responses in IPF elusive. In this study, we aimed identify hub genes for diagnosing and explore microenvironment IPF.
<title>Abstract</title> <bold>Objectives: </bold>This study aims to identify the risk factors for postoperative pulmonary complications (PPCs) in elderly patients undergoing major abdominal surgery and investigate relationship between patient-controlled analgesia (PCA) PPCs. <bold>Design: </bold>A retrospective study. <bold>Method:</bold>Clinical data demographic information of (aged ≥60 years) who underwent upper at First Affiliated Hospital Sun Yat-sen University from 2017 2019 were...
Background Hypotension is a risk factor for postoperative complications, but evidence from randomized trials does not support that higher blood pressure target always leads to optimized outcomes. The heterogeneity of underlying hemodynamics during hypotension may contribute these contradictory results. Exploring the subtypes can enable optimal management intraoperative hypotension. Methods This prospective, observational pilot study. Patients who were ≥ 45 years old and scheduled undergo...