Thomas Boucher

ORCID: 0000-0003-0617-4135
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • HIV Research and Treatment
  • Markov Chains and Monte Carlo Methods
  • Bone and Dental Protein Studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Shoulder Injury and Treatment
  • COVID-19 and healthcare impacts
  • Bayesian Modeling and Causal Inference
  • Total Knee Arthroplasty Outcomes
  • HIV-related health complications and treatments
  • Complex Systems and Time Series Analysis
  • Fault Detection and Control Systems
  • Stock Market Forecasting Methods
  • Shoulder and Clavicle Injuries
  • Advanced Statistical Methods and Models
  • Stochastic processes and statistical mechanics
  • Imbalanced Data Classification Techniques
  • Supramolecular Self-Assembly in Materials
  • Musculoskeletal pain and rehabilitation
  • Parvovirus B19 Infection Studies
  • Statistical Methods and Bayesian Inference
  • Aortic Disease and Treatment Approaches
  • Ecosystem dynamics and resilience
  • Autoimmune and Inflammatory Disorders Research
  • HIV/AIDS oral health manifestations
  • Primate Behavior and Ecology

Mount Sinai Hospital
2024

Icahn School of Medicine at Mount Sinai
2024

Johns Hopkins Medicine
2020-2022

Johns Hopkins University
2015-2022

Yeshiva University
2021

Albert Einstein College of Medicine
2020-2021

Texas A&M University – Commerce
2016-2020

Plymouth State University
2007-2009

"Test Equating, Scaling, and Linking: Methods Practices." Journal of the American Statistical Association, 102(478), pp. 762–763

10.1198/jasa.2007.s191 article EN Journal of the American Statistical Association 2007-06-01

Abstract Background Osteopontin (OPN) as a secreted signaling protein is dramatically induced in response to cellular injury and neurodegeneration. Microglial inflammatory responses the brain are tightly associated with neuropathologic hallmarks of neurodegenerative disease, but understanding molecular mechanisms remains several contexts poorly understood. Methods Micro-positron emission tomography (PET) neuroimaging using radioligands detect increased expression translocator (TSPO) receptor...

10.1186/s12974-020-01949-4 article EN cc-by Journal of Neuroinflammation 2020-09-17

Numerous studies have investigated the outcomes of outpatient total shoulder arthroplasty (TSA). However, some patients originally planned for surgery may unexpectedly require inpatient hospital stay, which can obscure distinction "outpatient" and "inpatient" cases. Ultimately, this inconsistent classification influence study results. The objectives were (1) to characterize differences in definition (hospital-defined [HDO] vs. same-day discharge [SDD]), (2) effect different definitions on...

10.1016/j.jseint.2024.08.191 article EN cc-by-nc-nd JSES International 2024-08-30

We consider a $\psi$-irreducible, discrete-time Markov chain on general state space with transition kernel $P$. Under suitable conditions the chain, kernels can be treated as bounded linear operators between spaces of functions or measures and Drazin inverse operator $I - P$ exists. The provides unifying framework for objects governing chain. This is applied to derive computational technique asymptotic variance in central limit theorems univariate higher-order partial sums. Higher-order sums...

10.1214/ecp.v12-1262 article EN cc-by Electronic Communications in Probability 2007-01-01

10.1016/j.spl.2008.12.018 article EN Statistics & Probability Letters 2008-12-31

The advent of Human Immunodeficiency Virus (HIV) antiretrovirals have reduced the severity HIV related neurological comorbidities but they nevertheless remain prevalent. Synaptic degeneration due to action several viral factors released from infected brain myeloid and glia cells inflammatory cytokines has been attributed manifestation a range cognitive behavioral deficits. contributions specific pro-inflammatory their interplay with in setting treatment persistence are incompletely...

10.3390/brainsci10060346 article EN cc-by Brain Sciences 2020-06-04

An 8-year-old boy with no significant past medical history presented to his pediatrician 5 days of fever, diffuse abdominal pain, and pallor. The referred the patient emergency department (ED), out concern for possible malignancy. Initial vital signs indicated tachypnea, tachycardia. Physical examination was marked distension, hepatosplenomegaly, tenderness in right upper lower quadrants. laboratory studies were notable pancytopenia as well an elevated erythrocyte sedimentation rate...

10.1542/peds.2019-2372 article EN PEDIATRICS 2020-06-12

Evidence suggesting that HIV pathogenesis differs by sex, a variable known to influence the extent and breadth of immune responses in health disease continues accumulate. Host factors promote or inhibit replication may do so way varies sex. Prior studies using cultured human macrophages demonstrated osteopontin (OPN)/secreted phosphoprotein-1 (SPP1) stimulates replication. To test whether OPN has same positive impact on virus at level tissues, we used humanized mice model low-level chronic...

10.3389/fviro.2021.690360 article EN cc-by Frontiers in Virology 2021-11-08

The state-space representations of certain nonlinear autoregressive time series are general state Markov chains. transitions a chain among regions in its can be modeled with the states finite chain. Stability is then informed by stationary distributions This approach generalizes some previous results.

10.1142/s0219493709002622 article EN Stochastics and Dynamics 2009-06-01

Introduced species influence the dynamics and structure of freshwater systems; understanding variables that shape introduced species’ distributions can aid in anticipating their spread. We examined multiple factors may distribution northern crayfish (Orconectes virilis (Hagen, 1870)), an species, New Hampshire, USA. Sampling occurred July to August 2010 20 lakes. tested catch per unit effort (CPUE) body size against lake trophic status, size, depth, shoreline development, as well substrate...

10.1139/cjz-2016-0152 article EN Canadian Journal of Zoology 2017-08-23

In Spring 2020, the United States epicenter of COVID-19 was New York City, in which borough Bronx particularly affected. This Fall, there has been a resurgence Europe and Midwestern States. We describe our experience transforming cardiac catheterization laboratories to accommodate an influx patients so as provide other hospitals with potential blueprint. transformed pre/postprocedural patient care areas into intensive step-down units maintained emergent invasive for ST-segment elevation...

10.25270/jic/20.00644 article EN Deleted Journal 2020-12-22

The impact of long-memory on the Before-After-Control-Impact (BACI) design and a commonly used nonparametric alternative, Randomized Intervention Analysis (RIA), is examined. It shown corrections based short-memory processes are not adequate. Long-memory series also known to exhibit spurious structural breaks that can be mistakenly attributed an intervention. Two examples from literature as illustrations.

10.4236/ojs.2017.75054 article EN Open Journal of Statistics 2017-01-01
Coming Soon ...