A5090083078- Emergency and Acute Care Studies
- Frailty in Older Adults
- Infection Control in Healthcare
- Poisoning and overdose treatments
- Drug-Induced Hepatotoxicity and Protection
- Clostridium difficile and Clostridium perfringens research
- Disaster Management and Resilience
- Antibiotic Use and Resistance
- Trauma and Emergency Care Studies
- Respiratory Support and Mechanisms
- Disaster Response and Management
- Cardiac Arrest and Resuscitation
- Thermal Regulation in Medicine
- Cannabis and Cannabinoid Research
- Hip and Femur Fractures
Washington University in St. Louis
2009-2018
Objective. To determine the effect of activated charcoal (AC) on acetaminophen (APAP) absorption kinetics when administered at 1, 2, or 3 h after combined oral overdose with oxycodone. Methods. IRB-approved, prospective cross-over study nine healthy human volunteers ingesting 5 g APAP + 0.5 mg/kg oxycodone each four days. On control day, subjects received no AC. remaining days, ingested 50 AC drug ingestion. We measured serum concentration hourly from 0 through 8 and compared basic...
The COVID-19 pandemic demonstrated the need for inexpensive, easy-to-use, rapidly mass-produced resuscitation devices that could be quickly distributed in areas of critical need. In-line miniature ventilators based on principles fluidics ventilate patients by automatically oscillating between forced inspiration and assisted expiration as airway pressure changes, requiring only a continuous supply pressurized oxygen. Here, we designed three ventilator models to operate specific ranges along...