A5086219367- MicroRNA in disease regulation
- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Chromosomal and Genetic Variations
- CRISPR and Genetic Engineering
- Prenatal Screening and Diagnostics
- Genomics and Rare Diseases
- RNA modifications and cancer
- ATP Synthase and ATPases Research
- Circular RNAs in diseases
- Hemoglobinopathies and Related Disorders
- Nanocluster Synthesis and Applications
- Extracellular vesicles in disease
- Genomic variations and chromosomal abnormalities
- Mesenchymal stem cell research
- Intraocular Surgery and Lenses
- Osteoarthritis Treatment and Mechanisms
- Genetics and Neurodevelopmental Disorders
- Connexins and lens biology
- Autism Spectrum Disorder Research
- Iron Metabolism and Disorders
- RNA and protein synthesis mechanisms
- Hematological disorders and diagnostics
- Reconstructive Facial Surgery Techniques
- Ocular Disorders and Treatments
Hamedan University of Medical Sciences
2020-2025
Tarbiat Modares University
2020-2023
National Institute of Genetic Engineering and Biotechnology
2011-2012
Introduction. The etiology of male infertility characterized by non-obstructive azoospermia is largely unknown, especially at the molecular level. Identifying dysregulated microRNAs (miRNAs) in would be useful to achieve a more profound understanding its pathogenesis. Methods. Small RNA sequencing was performed on testicular tissues 10 nonobstructive azoospermic patients with Sertoli cell only syndrome (SCOS) and 8 obstructive individuals normal spermatogenesis. expressions two miRNAs were...
Introduction: MiRNA expression alterations are closely related to growth, proliferation, and cell development. In addition, miR-187 has been found regulate cellular proliferation. Further, spermatogenesis is a highly complicated process which regulated through several genes targeted by miRNAs. However, no study completely addressed the etiology of spermatogenic impairments. Accordingly, present examined pattern Homo sapiens (human) microRNA (hsa-mir-187) in testicular biopsies infertile men...
Abstract Background The etiology of male infertility accompanied by azoospermia is largely unknown especially at the molecular level. Identifying global expression profile dysregulated microRNAs (miRNAs) in would be useful to achieve a more profound understanding pathogenesis. Methods Small RNA sequencing was performed on testicular tissues 10 nonobstructive azoospermic patients with Sertoli cell only syndrome (SCOS) and those 8 obstructive individuals. 4 miRNAs validated quantitative...
The purpose of this experimental study was to investigate the genetic etiology congenital cataract (CC) manifesting an autosomal recessive pattern inheritance in four Iranian families. Affected individuals and their normal first-degree relatives each family were included present study. genomic DNA blood samples extracted from all participants, one affected member belonging subjected Whole Exome Sequencing (WES). Using bidirectional Sanger sequencing, identified variants validated by...
Background: Robertsonian translocations (RobTs) are one of the major chromosomal abnormalities which lead to spontaneous abortion. They occur in human population at rate 1 1000 live infants. In this paper, a family carrying rare RobTs was presented and some features all kinds were reviewed.
 Case Presentation: A couple with history three miscarriages referred Omid Health Clinic Hamadan, Iran. The karyotype woman 45,XX, rob(14;15)(q10;q10) she exhibited phenotypically good health....