Zhanyu Wu

ORCID: 0000-0003-0635-0071
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Hip disorders and treatments
  • Total Knee Arthroplasty Outcomes
  • Bone and Joint Diseases
  • Knee injuries and reconstruction techniques
  • Bone fractures and treatments
  • Orthopedic Infections and Treatments
  • Hip and Femur Fractures
  • Osteoarthritis Treatment and Mechanisms
  • Asthma and respiratory diseases
  • Law, AI, and Intellectual Property
  • Artificial Intelligence in Law
  • Infectious Diseases and Tuberculosis
  • Mesenchymal stem cell research
  • Shoulder Injury and Treatment
  • Lower Extremity Biomechanics and Pathologies
  • Infective Endocarditis Diagnosis and Management
  • Titanium Alloys Microstructure and Properties
  • Bone health and osteoporosis research

Guiyang Medical University
2018-2025

Affiliated Hospital of Guizhou Medical University
2018-2025

West China Hospital of Sichuan University
2019-2020

Sichuan University
2019-2020

Yueyang Hospital
2019-2020

Shanghai University of Traditional Chinese Medicine
2019-2020

Massachusetts General Hospital
2019-2020

Core decompression is a common method for treating early osteonecrosis of the femoral head (ONFH). However, surgical procedure cumbersome due to lack appropriate instruments. This study aims modify instruments improve surgery efficiency. A total 28 patients with ONFH treated core were enrolled. 13 cases new and other 15 traditional methods. The convenience was evaluated by comparing evaluation indicators. multi-functional reduced number fluoroscopy, shorted operation time, improved delivery...

10.1038/s41598-025-90551-w article EN cc-by Scientific Reports 2025-02-19

Knee osteoarthritis (KOA) is one of the most common chronic diseases in elderly and primary cause loss motor function disability this population. Exercise therapy a core, basic matureand treatment method treating patients with KOA. “strongly recommended” or “recommended” diagnosis guidelines many countries, scholars advocate exercise as preferred rehabilitation for KOA patients. However, poor long-term adherence serious problem affecting therapeutic effect mature treatment. The objective...

10.1186/s12891-018-2200-x article EN cc-by BMC Musculoskeletal Disorders 2018-07-27

To analyze the impact of femoral neck cortical bone defect induced by core decompression on postoperative biomechanical stability using finite element method.Five models (FEMs) were established, including standard operating model and four defects at different portions (anterior, posterior, superior, inferior). The maximum stress proximal femur was evaluated during normal walking downstairs.Under both weight-bearing conditions, values five as follows: (inferior) > (superior) (posterior)...

10.1155/2022/3667891 article EN cc-by BioMed Research International 2022-05-20

Abstract Background: Osteonecrosis of the femoral head (ONFH) is a common disease that greatly affects quality life patients. Repair necrotic area key to successful treatment. Currently, combination stem cell transplantation and decompression used clinically promote repair areas based on characteristics cells. However, considerable number patients do not achieve satisfactory outcome in terms area, it very important determine reasons for poor curative effect. The aim this study was...

10.21203/rs.2.18114/v3 preprint EN cc-by Research Square (Research Square) 2020-01-15

Background When high tibial osteotomy is performed for genu varus deformity, it not easy to determine the accurate placement of plate. Purpose To a simple way assess position plate, provide more effective mechanical support and reduce risk implant rupture vascular injury. Material Methods Two human anatomical marks, patellar ligament semimembranosus, were connected divided into four parts identify points Ⅰ, Ⅱ, Ⅲ. These determined areas Tomofix placement: anterior, anterolateral, lateral....

10.1177/02841851231223661 article EN Acta Radiologica 2024-01-10

<abstract><p>Knee medial compartment osteoarthritis is effectively treated by a open-wedge high tibial osteotomy (MOWHTO). The feasibility and safety of MOWHTO for mild lateral meniscal tears are unknown. This study examined the knee joint weight-bearing line ratio (WBLr) adjustment during with injuries. We used healthy adult male's lower extremities computed tomography scans magnetic resonance imaging images to create normal fine element (FE) model. Based on this model, we...

10.3934/mbe.2024237 article EN cc-by Mathematical Biosciences & Engineering 2024-01-01

Text embeddings from large language models (LLMs) have achieved excellent results in tasks such as information retrieval, semantic textual similarity, etc. In this work, we show an interesting finding: when feeding a text into the embedding LLMs, obtained will be able to aligned with key tokens input text. We first fully analyze phenomenon on eight LLMs and that is universal not affected by model architecture, training strategy, method. With deeper analysis, then find main change space...

10.48550/arxiv.2406.17378 preprint EN arXiv (Cornell University) 2024-06-25

Medial opening wedge high tibial osteotomy (HTO) is successful in the treatment of knee osteoarthritis with medial compartment stenosis and varus deformity, but patella infera main complication. This study aims to design a new open scheme, transtibial tuberosity-high (TT-HTO), which can fully protect patellar tendon insertion. In addition, area surface volume were evaluated TT-HTO, biplanar distal tuberosity (biplanar-DTO), uniplanar-DTO evaluate potential advantages this technology bone...

10.1111/os.13562 article EN cc-by-nc-nd Orthopaedic Surgery 2022-11-23

Abstract Background The clinical outcomes of open-wedge high tibial osteotomy (OWHTO) for medial knee osteoarthritis primarily depend on the corrective precision. present study aimed to determine efficacy and feasibility laser correction technology with an ordinary pen surgical instrument box. Methods This prospective randomized trial included 71 patients randomly divided into ( n = 36) traditional groups 35). In group, hip centre, (Fujisawa point), ankle centre were located preoperatively...

10.1186/s12891-022-05993-4 article EN cc-by BMC Musculoskeletal Disorders 2022-11-26

Postoperative deep infection is usually identified by microbial culture. However, frequent false-negative results have severely limited effective treatment. We report a rare case of intra-articular and paravertebral after total knee arthroplasty caused Mycoplasma hominis Ureaplasma urealyticum , with multiple negative culture results. Eventually, the pathogens were using metagenomic high-throughput sequencing, patient was successfully treated several “old” antibiotics. analyze clinical...

10.3928/01477447-20230531-04 article EN Orthopedics 2023-06-05

Abstract Background: Osteonecrosis of the femoral head (ONFH) is a common disease that greatly affects quality life patients. Repair necrotic area key to successful treatment. Currently, combination stem cell transplantation and decompression used clinically promote repair areas based on characteristics cells. However, considerable number patients do not achieve satisfactory outcome in terms area, it very important determine reasons for poor curative effect. The aim this study was...

10.21203/rs.2.18114/v2 preprint EN cc-by Research Square (Research Square) 2019-12-16

Abstract Background: Osteonecrosis of the femoral head (ONFH) is a common disease that greatly affects quality life patients. Repair necrotic area key to treatment.At present, combination stem cell transplantation and decompression used clinically promote repair areas through characteristics cells. However, considerable number patients cannot achieve satisfactory outcome in repairing area. It very important find out reasons for poor curative effect. The aim this study was investigate...

10.21203/rs.2.18114/v1 preprint EN cc-by Research Square (Research Square) 2019-12-03

Abstract Background: The clinical outcomes of open-wedge high-tibial osteotomy (OWHTO) for medial knee osteoarthritis depend mainly on the precision correction. present study aimed to determine efficacy and feasibility simple navigation technology with an ordinary laser pen surgical instrument box. Methods : Seventy-one patients were randomly divided into (n=36) traditional groups (n=35). In group, hip, (Fujisawa point), ankle centers located preoperatively using lid leg was aligned pen....

10.21203/rs.3.rs-1341575/v1 preprint EN cc-by Research Square (Research Square) 2022-02-16

Background and Objective: Elderly patients treated for femoral shaft fractures have a higher risk of hip fracture. We hypothesized that intramedullary nails protecting the neck reduce subsequent fracture allow patient to avoid challenging reoperation. This study aims analyze biomechanical stability using with or without protection through finite element analysis.Methods: Thirty models (FEMs) were established, including five different conditions fracture: Fracture healing, Proximal...

10.2139/ssrn.4095679 article EN SSRN Electronic Journal 2022-01-01
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