A5032242387- Microfluidic and Bio-sensing Technologies
- 3D Printing in Biomedical Research
- Orbital Angular Momentum in Optics
- Microgrid Control and Optimization
- Frequency Control in Power Systems
- Single-cell and spatial transcriptomics
- Neuroscience and Neural Engineering
- Autonomous Vehicle Technology and Safety
- Micro and Nano Robotics
- Cell Image Analysis Techniques
- Vehicle emissions and performance
- Face and Expression Recognition
- Digital Holography and Microscopy
- Gene expression and cancer classification
- Advanced MEMS and NEMS Technologies
- Mitochondrial Function and Pathology
- Nanoplatforms for cancer theranostics
- Cellular Mechanics and Interactions
- Traffic control and management
- Advanced Nanomaterials in Catalysis
- Digital Imaging for Blood Diseases
- Neural Networks Stability and Synchronization
- Electrohydrodynamics and Fluid Dynamics
- Vehicle Dynamics and Control Systems
- Nanoparticles: synthesis and applications
King Fahd University of Petroleum and Minerals
2022-2025
Dhahran Health Center
2024
City University of Hong Kong
2017-2022
Xi'an Jiaotong University
2014-2015
The potential use of gold nanoparticles (AuNPs) in healthcare research has increased dramatically recent years, owing to advancements their synthesis techniques, including green synthesis. Although Clerodendrum trichotomum is a popular medicinal plant that harbors many bioactive phytochemicals various parts the world, AuNPs using this precious still under investigation. Therefore, study aimed explore from C. Thunberg leaves (CTT-AuNPs) and antibacterial cytotoxic properties. were synthesized...
In many cell surgery applications, must be oriented properly such that the microsurgery tool can access target components with minimum damage to cell. this paper, a scheme for out of image plane orientation control suspended biological cells using robotic controlled optical tweezers is presented orientation-based surgery. Based on our previous work planar rotation tweezers, dynamic model out-of-plane formulated by T-matrix approach. Vision-based algorithms are developed extract angles, based...
Mitochondrial transfer is a spontaneous process to restore damaged cells in various pathological conditions. The of mitochondria cell therapy products before their administration can enhance therapeutic outcomes. However, the low efficiency previously reported methods limits clinical application. Here, we developed droplet microfluidics–based mitochondrial technique that achieve high-efficiency and high-throughput quantitative single cells. Because are essential for muscles, myoblast muscle...
High dimensionality and small sample sizes, their inherent risk of overfitting, pose great challenges for constructing efficient classifiers in microarray data classification. Therefore a feature selection technique should be conducted prior to classification enhance prediction performance. In general, filter methods can considered as principal or auxiliary mechanism because simplicity, scalability, low computational complexity. However, series trivial examples show that result less accurate...
Single cell surgery such as manipulation or removal of subcellular components or/and organelles from single cells is increasingly used for the study diseases and their causes in precision medicine. This paper presents a robotic system to achieve automated organelle biopsy with dimensions less than 20 μm diameter. The complexity spatial detection position reduced by patterning using microfluidic chip device. A sliding mode nonlinear controller developed enable extraction organelles,...
Mitochondrial dysfunction is considered to be an important factor that leads aging and premature diseases. Transferring mitochondria cells emerging promising technique for the therapy of mitochondrial deoxyribonucleic acid (mtDNA)-related This paper presents a unique method controlling quality quantity transferred single using automated optical tweezer-based micromanipulation system. The proposed can automatically, accurately, efficiently collect transport healthy cells, recipient then take...
Automated microinjection systems for suspension cells have been studied years. Nevertheless, adherent still suffer from laborious manual operations and low productivity. This paper presents a new automated system with high productivity cells. enhances through four approaches. First, are detected automatically to replace selections. Second, the injection paths of optimized rapidly save time. Third, penetration depth is adjusted adaptively according moving plane dish holder plate. Finally,...
Summary Multiple degrees‐of‐freedom (multi‐DOF) cell orientation control is a vital important technique involved in single surgery applications. Currently, few studies have been performed toward automation of multi‐DOF using robotically controlled optical tweezers. In this paper, robust framework developed to perform rotational with consideration model uncertainties and external disturbances. Both simulation experimental are presented illustrate the performance proposed strategy. The main...
Precise intracellular delivery is essential for many biomedical applications, such as genome-editing and mechanism investigation. This article presents the development of an automated approach using a robot-aided microscope system with 3-D reconstruction information. A series optical section images sampled by objective lens movement restored on computer. After several processes, including deconvolution, segmentation, images, optimal position can be acquired via geometry analysis based...
Intracellular surgery suffers from a low success rate due to the lack of three-dimensional (3-D) position feedback selected organelles. In this study, we developed novel robot-aided microscopy system and 3-D reconstruction algorithm conduct intracellular with information. A series optical sections along vertical direction was obtained by lens movement. model specimen realized after several deconvolution, segmentation, processes. Simulations experiments were performed verify accuracy proposed...
In this paper, we present a precise robot-aided single-cell surgery system to perform biopsy for cells <25 μm in diameter. A microfluidic chip is designed arrange upto 100 individual an array. micropipette mounted onto 3-DOF micromanipulator and computer mouse-operated high-precision XY stage developed high-throughput biopsy. The evaluated experimentally by extracting two organelles from adherent patterned chip. fluorescent-labeled nucleus mitochondria of human foreskin fibroblast are...
Kochiae Fructus has been widely used in Chinese Herbal medicine to treat various diseases. We report a rapid and eco-friendly approach for cerium oxide (CeO2) nanoparticles (NPs) synthesis using the extract of medicinally important plant "Kochiae Fructus", synthesized NPs were named KF-CeO2 NPs.Various spectroscopic approaches such as transmission electron microscope (TEM), powder X-ray diffraction (XRD), energy-dispersive X-Ray (EDX) characterize effectively. The antibacterial biofilm...