A5039793905- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Collagen: Extraction and Characterization
- Electrospun Nanofibers in Biomedical Applications
- Conducting polymers and applications
- Quantum Dots Synthesis And Properties
- Tactile and Sensory Interactions
- Retinal Development and Disorders
- Advanced Sensor and Energy Harvesting Materials
- Tissue Engineering and Regenerative Medicine
- Hydrogels: synthesis, properties, applications
Tampere University
2016-2025
Newcastle University
2025
Tampere University of Applied Sciences
2024
Photocrosslinkable bioinks have gained interest in 3D bioprinting due to their versatility and ease of use. However, a specific functional group, such as methacrylate or photo-click chemistry, is needed the polymer backbone enable photocrosslinking. Methacrylated gellan gum (GGMA) precursor has been proven possess good rheological properties for an injectable hydrogel its inherent viscosity. It can also be photocrosslinked situ at target site. Unfortunately, GGMA precursors alone are unable...
The major challenges of hyaluronic acid-based bioinks in extrusion-based three-dimensional bioprinting are poor printability and low printing accuracy. To tackle the challenges, we developed a bioink which two components blended: gallic acid-functionalized acid (HAGA) methacrylate (HAMA). In precursor phase, blend's HAGA component enables pH-dependent viscosity modulation that results improved injectability at physiological temperature. Postprinting, HAMA is photocrosslinked to create true...
Age-related macular degeneration (AMD) is a leading cause of blindness in developed countries, characterised by the retinal pigment epithelium (RPE), pigmented cell monolayer that closely interacts with photoreceptors. RPE transplantation thus considered very promising therapeutic option to treat this disease. In work, porous honeycomb-like films are for first time investigated as scaffold materials human embryonic stem cell-derived (hESC-RPE). By changing conditions during film preparation,...
The printability of a photocross-linkable methacrylated gelatin (GelMA) bioink with an extrusion-based 3D bioprinter is highly affected by the polymer concentration and printing temperature. In this work, we developed gallic acid (GA)-functionalized GelMA ink to improve at room physiological temperatures enable tissue adhesion antioxidant properties. We introduced sequential cross-linking approach using catechol–Fe3+ chelation, followed photocross-linking. results show that formulation 0.5%...
Abstract Photocrosslinking of hydrogels with non‐pulsed red light offers improved biocompatibility and deep tissue penetration in contrast to traditional UV‐initiated methods. However, fabricated upon red‐light excitation are always colored by a photoinitiator, limiting their use applications requiring high optical transparency, such as (bio)sensors, ophthalmological applications, or wound dressings. Additionally, the cytotoxicity photoinitiator is concern, especially bioapplications....
For modern tissue engineering, we need not only develop new hydrogels but also suitable processing methods for them. Polypeptides and polysaccharides are potential candidates because they can be methacrylated, processed before photocross-linking, yielded into with given shape form. In this study, successfully methacrylated collagen, gelatin, hyaluronan, alginate to 30 60% degree of modification. We studied compositions (i.e., precursors) investigate their processability. The precursors...
This study describes the development of bioadhesive hydrogels as biomaterial inks, which combine catechol chemistry and metal coordination using gallic acid hyaluronic acid.
In biomedical sciences, there is a demand for electronic skins with highly sensitive tactile sensors that have applications in patient monitoring, human–machine interfaces, and on‐body sensors. Sensor fabrication requires high‐performance conductive surfaces are transparent, breathable, flexible, easy to fabricate. It also preferable if the electrodes easily processable as wastes, example, degradable. this work, design of hydrophilic silanol/amine‐terminated poly(caprolactone‐urethane)...