Manisha Nair

ORCID: 0000-0003-0660-5054
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About
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Research Areas
  • Global Maternal and Child Health
  • Maternal and fetal healthcare
  • Maternal and Perinatal Health Interventions
  • Pregnancy and preeclampsia studies
  • Child Nutrition and Water Access
  • Cardiovascular Issues in Pregnancy
  • Grief, Bereavement, and Mental Health
  • Maternal Mental Health During Pregnancy and Postpartum
  • Global Health Care Issues
  • Poverty, Education, and Child Welfare
  • Food Security and Health in Diverse Populations
  • Trauma and Emergency Care Studies
  • Healthcare Systems and Reforms
  • Global Health Workforce Issues
  • Cardiac Structural Anomalies and Repair
  • Reproductive Health and Contraception
  • Pregnancy-related medical research
  • Global Health and Epidemiology
  • Innovations in Medical Education
  • Congenital Heart Disease Studies
  • Global Public Health Policies and Epidemiology
  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Global Health and Surgery
  • Leptospirosis research and findings

University of Oxford
2016-2025

Nuffield Orthopaedic Centre
2023-2024

Nuffield Health
2018-2024

Medisch Centrum Haaglanden
2020

Texas A&M University
2018

New Cross Hospital
2017

Wolverhampton Hospital
2017

NHS Blood and Transplant
2017

John Radcliffe Hospital
2017

Guy's and St Thomas' NHS Foundation Trust
2017

Objectives To examine the association between maternal anaemia and adverse infant outcomes, to assess feasibility of conducting epidemiological studies through Indian Obstetric Surveillance System–Assam (IndOSS-Assam). Design Retrospective cohort study using anonymised hospital records. Exposure: iron deficiency anaemia; outcomes: postpartum haemorrhage (PPH), low birthweight, small-for-gestational age babies, perinatal death. Setting 5 government medical colleges in Assam. Study population...

10.1136/bmjgh-2015-000026 article EN cc-by-nc BMJ Global Health 2016-04-01

The World Health Organization (WHO) undertook an extensive and elaborate process to develop eight Global Standards improve quality of health care services for adolescents. objectives this article are present the their method development.The were developed through a four-stage process: (1) conducting needs assessment; (2) developing criteria; (3) expert consultations; (4) assessing usability. Needs assessment involved meta-review systematic reviews two online global surveys in 2013, one with...

10.1016/j.jadohealth.2015.05.011 article EN cc-by Journal of Adolescent Health 2015-08-20

Abstract Background Cardio-metabolic diseases (CMDs) are a growing public health problem, but data on incidence, trends, and costs in developing countries is scarce. Comprehensive standardised surveillance for non-communicable was recommended at the United Nations High-level meeting 2011. Aims: To develop model system CMDs risk factors that could be adopted continued assessment of burdens from multiple perspectives South-Asian countries. Methods Design: Hybrid with two cross-sectional serial...

10.1186/1471-2458-12-701 article EN cc-by BMC Public Health 2012-08-28

<h3>Objectives</h3> To describe clinical characteristics and preoperative management of a national cohort infants with Hirschsprung9s disease (HD). <h3>Design</h3> Population-based study all live-born HD born in the UK Ireland from October 2010 to September 2012. <h3>Setting</h3> All 28 paediatric surgical centres Ireland. <h3>Participants</h3> 305 presenting before 6 months age histologically proven HD. <h3>Main outcome measures</h3> Incidence, including gestational age, birth weight,...

10.1136/archdischild-2016-311872 article EN cc-by Archives of Disease in Childhood 2017-03-09

Objective To investigate the factors associated with maternal death from direct pregnancy complications in UK. Design Unmatched case–control analysis. Setting All hospitals caring for pregnant women Population A total of 135 who died (cases) between 2009 and 2012 eclampsia, pulmonary embolism, severe sepsis, amniotic fluid peripartum haemorrhage, using data Confidential Enquiry into Maternal Death, another 1661 survived (controls) caused by these conditions (2005–2013), UK Obstetric...

10.1111/1471-0528.13279 article EN cc-by-nc BJOG An International Journal of Obstetrics & Gynaecology 2015-01-09

Objectives To assess the rate of stillbirth and associated risk factors across nine states in India. Design Secondary analysis cross-sectional data from Indian Annual Health Survey (2010–2013). Setting Nine India: Madhya Pradesh, Chhattisgarh, Rajasthan, Uttarakhand, Jharkhand, Odisha, Bihar, Assam Uttar Pradesh. Participants 886 505 women, aged 15–49 years. Main outcome measures Stillbirth with 95% CI. Adjusted OR to examine associations between (1) socioeconomic, behavioural biodemographic...

10.1136/bmjopen-2018-022583 article EN cc-by BMJ Open 2018-11-01

Unsafe abortion is a preventable cause of maternal mortality. While studies report high number abortions in India, the population-level rates unsafe and their risk factors are not well understood. Our objective was to analyse for abortion-related death India.We conducted secondary analysis data from 1 876 462 pregnant women aged 15-58 years nine states Indian Annual Health Survey (2010-2013). We calculated rate mortality with 95% CI. Multivariable logistic regression models examined...

10.1136/bmjgh-2019-001491 article EN cc-by BMJ Global Health 2019-05-01

Indirect maternal deaths outnumber direct due to obstetric causes in many high-income countries, and there has been a significant increase the proportion of indirect medical low- middle-income countries. This review presents detailed analysis UK perspective on trends issues related care There no decrease rate since 2003. In 2011-2013, 68% all were causes, cardiac disease was single largest cause. The major identified women who died from an cause lack clarity about which professional should...

10.1177/1753495x16689444 article EN Obstetric Medicine 2017-02-01

Summary The study objectives were to examine the association of maternal haemoglobin with stillbirth and perinatal death in a multi‐ethnic population England. We conducted retrospective cohort analysis using anonymised maternity data from 14 001 women singleton pregnancies ≥24 weeks’ gestation giving birth between 2013 2015 two hospitals ‐ Royal Wolverhampton NHS Trust Guy's St Thomas’ Foundation Trust. Multivariable logistic regression analyses undertaken analyse associations at first visit...

10.1111/bjh.14961 article EN cc-by-nc British Journal of Haematology 2017-10-26

Introduction As maternal deaths become rarer, monitoring near-miss or severe morbidity becomes important as a tool to measure changes in care quality. Many calls have been made use routinely available hospital administration data monitor the quality of maternity care. We investigated 1) feasibility developing an English Maternal Morbidity Outcome Indicator (EMMOI) by reproducing Australian indicator using data, 2) impact modifications address potential issues, 3) reliability indicator....

10.1371/journal.pone.0153370 article EN cc-by PLoS ONE 2016-04-07

Objectives To identify the risk factors for and adverse newborn outcomes associated with maternal deaths from direct indirect causes in UK . Design Unmatched case–control analysis. Setting All hospitals caring pregnant women Population Comprised 383 who died (cases) or 2009 to 2013 (Confidential Enquiry into Maternal Deaths ) 1516 did not have any life‐threatening complications during pregnancy childbirth (controls) obtained Obstetric Surveillance System ( UKOSS ). Methods Multivariable...

10.1111/1471-0528.13978 article EN cc-by-nc BJOG An International Journal of Obstetrics & Gynaecology 2016-03-10

Objective To examine the risk factors for pregnancy-related death in India’s nine Empowered Action Group (EAG) states. Design Secondary data analysis of Indian Annual Health Survey (2010–2013). Setting Nine states: Assam, Bihar, Chhattisgarh, Jharkhand, Madhya Pradesh, Odisha, Rajasthan, Uttar Pradesh and Uttarakhand. Participants 1 989 396 pregnant women. Methods Maternal mortality ratio (MMR), overall each state, with 95% CI was calculated. Stepwise multivariable logistic regression used...

10.1136/bmjopen-2020-038910 article EN cc-by BMJ Open 2020-08-01

Abstract Objective This study aimed to investigate the incidence of and risk factors for stillbirth in an Indian population. Methods We conducted a secondary data analysis hospital‐based cohort from Maternal Perinatal Health Research collaboration, India (MaatHRI), including pregnant women who gave birth between October 2018–September 2023. Data 9823 singleton pregnancies recruited 13 hospitals across six states were included. Univariable multivariable Poisson regression performed examine...

10.1002/ijgo.15367 article EN cc-by International Journal of Gynecology & Obstetrics 2024-01-17

South Asians have a higher risk for coronary artery disease (CAD) due to both pathophysiological and life course-related factors. We performed literature search used qualitative synthesis present evidence CAD factors among Asians. A large proportion of the can be explained by conventional However, several conditioning such as education, socioeconomic status, fetal programming, early influences may contribute excess in Asians, suggesting need course approach. Evidence on unconventional is...

10.1016/j.gheart.2012.09.001 article EN cc-by-nc-nd Global Heart 2012-10-16

Previous studies showed a higher risk of maternal morbidity amongst black and other minority ethnic (BME) groups, but were unable to investigate whether this excess was concentrated within specific BME groups in the UK. Our aim analyse risks reasons for any disparity.Unmatched case-control analysis using data from United Kingdom Obstetric Surveillance System (UKOSS), February 2005-January 2013. Cases 1,753 women who experienced severe during peripartum period. Controls 3,310 delivered...

10.1371/journal.pone.0095086 article EN cc-by PLoS ONE 2014-04-17

Background Studies of maternal mortality have been shown to result in important improvements women’s health. It is now recognised that countries such as the UK, where deaths are rare, study near-miss severe morbidity provides additional information aid disease prevention, treatment and service provision. Objectives To (1) estimate incidence specific morbidities; (2) assess contribution existing risk factors incidence; (3) describe different interventions their impact on outcomes costs; (4)...

10.3310/pgfar04090 article EN publisher-specific-oa Programme Grants for Applied Research 2016-06-01

The physiological fall in haemoglobin concentration from the 1st to 3rd trimester of pregnancy is often quoted as 5 g/L. However, other studies have suggested varying levels between 8 and 13 We evaluated change trimesters a multi-ethnic population pregnant women.A retrospective cohort analysis 7054 women with singleton pregnancies, giving birth during 2013-15 single urban maternity unit England. calculated changes using first reference point. was stratified into sub-groups explore any...

10.1186/s12884-019-2495-0 article EN cc-by BMC Pregnancy and Childbirth 2019-10-16

RRH: Rural and Remote Health. Published article number: 2311 - What influences the decision to undergo institutional delivery by skilled birth attendants? A cohort study in rural Andhra Pradesh, India

10.22605/rrh2311 article EN cc-by Rural and Remote Health 2012-11-09

Application of the tenth revision International Classification Diseases (ICD) to deaths during pregnancy, childbirth, and puerperium (ICD-Maternal Mortality [MM]) divides maternal into direct obstetric (ie, resulting from complications interventions, omissions, incorrect treatment, or a chain events any above) indirect previous existing disease, disease that developed pregnancy was not due causes, but aggravated by physiological effects pregnancy).1WHOThe WHO application ICD-10 childbirth...

10.1016/s2214-109x(17)30426-6 article EN cc-by-nc-nd The Lancet Global Health 2017-11-11

Objective This study aimed to examine the factors associated with maternal mortality among women aged ≥35 years. Design Unmatched population based case–control study. Setting United Kingdom. Population Between 2009 and 2012, 105 cases of deaths years were extracted from surveillance database MBRRACE ‐ UK confidential enquiries into in . In addition, 766 controls identified Obstetric Surveillance System (2005–2012). Methods Risk known be morbidity for which data available examined their...

10.1111/1471-0528.14216 article EN cc-by-nc BJOG An International Journal of Obstetrics & Gynaecology 2016-07-13
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