- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Pelvic floor disorders treatments
- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Neuropeptides and Animal Physiology
- Nitric Oxide and Endothelin Effects
- Neuroscience of respiration and sleep
- Urinary Tract Infections Management
- Neuroendocrine regulation and behavior
- Tissue Engineering and Regenerative Medicine
- Receptor Mechanisms and Signaling
- Pain Mechanisms and Treatments
- Ion Channels and Receptors
- Bladder and Urothelial Cancer Treatments
- Circadian rhythm and melatonin
- Prostate Cancer Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- Cannabis and Cannabinoid Research
- Pharmacology and Obesity Treatment
- Gastrointestinal motility and disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Pain Management
- Intracranial Aneurysms: Treatment and Complications
- Aldose Reductase and Taurine
Sydney Local Health District
2025
Lund University
2007-2024
Wake Forest University
2015-2024
Forest Institute
2014-2024
Atrium Health Wake Forest Baptist
2012-2024
California Institute for Regenerative Medicine
2024
University of Pittsburgh
2010-2023
University Medical Center of the Johannes Gutenberg University Mainz
2023
Johannes Gutenberg University Mainz
2023
King's College Hospital
2023
A sensitive device for recording of mechanical activity in isolated small blood vessels with calibres down to 100 μm is described. This equipment was used examine the properties rat cerebral arteries. The ultrastructure preparations investigated by light‐, transmission, and scanning electron‐microscopy. In general walls middle basilar arteries consisted 3 layers smooth muscle cells, which occupied approximately 80% total wall thickness. present technique preserved integrity vessel caused no...
No AccessJournal of UrologyInvestigative Urology1 Nov 2008Urine Derived Cells are a Potential Source for Urological Tissue Reconstructionis companion ofIndications Preoperative Prostate Biopsy in Patients Undergoing Radical Cystoprostatectomy Bladder CancerUrethrectomy Following Cystectomy Cancer Men: Practice Patterns and Impact on SurvivalSerosa Lined Tapered Ileum as Primary Secondary Continence Mechanism Various Catheterizable Pouches Yuanyuan Zhang, Elena McNeill, Hong Tian, Shay Soker,...
Human detrusor strips were obtained from patients undergoing reimplantation of ureters because reflux, transvesical prostatectomy, or cysto-urethrectomy en bloc bladder malignancy. The electrically stimulated. A frequency-dependent contractant response was that potentiated by physostigmine and abolished tetrodotoxin. maximum approximately equaled acetylcholine in a concentration. In most preparations without known functional disturbances, atropine (0.01 to 0.1 microM) had marked inhibitory...
Cystometries were performed in normal rats and with bladder hypertrophy due to infravesical outflow obstruction. Investigations the presence absence of anesthesia. pentobarbital anesthesia depressed spontaneous contractile activity micturition reflex, thereby making measurements other variables, such as capacity residual volume, impossible. In conscious animals obstruction led development increased capacity, marked unstable detrusor contractions. The model seems be well suited for further...
The possible existence of a β 3 ‐adrenergic receptor (β ‐AR) in the human detrusor muscle was investigated by vitro functional studies and analysis mRNA expression. Isoprenaline, noradrenaline adrenaline each produced concentration‐dependent relaxation detrusor. rank order for their relaxing potencies isoprenaline (pD 2 6.37±0.07) 6.07±0.12) 5.88±0.11). Neither dobutamine 1 ‐ ‐AR agonist) nor procaterol any significant at concentrations up to 10 −5 M . BRL37344A, CL316243 CGP‐12177A...
No AccessJournal of Urology1 Aug 1983Effects Prazosin in Patients with Benign Prostatic Obstruction H. Hedlund, K.-E. Andersson, and A. Ek HedlundH. Hedlund More articles by this author , AnderssonK.-E. Andersson EkA. View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)51106-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Prazosin, a selective alpha-1-adrenoceptor blocker, was used double-blind crossover...
✓ Sixty consecutive patients with a ruptured supratentorial aneurysm underwent operation during the acute stage, 56 of them within 72 hours after first bleed, one on 4th day, and three 5th day. Six were classified preoperatively in Hunt Hess neurological Grade I, 39 II, 11 III, four IV or V. Nine had severe intracerebral hematomas, patient subdural hematoma. After was clipped, nimodipine applied to exposed arterial segments 2.5 × 10 −5 M solution for minutes. Subsequently, all received...