Manuela Krumrey-Langkammerer

ORCID: 0000-0003-0667-4156
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About
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Research Areas
  • Autoimmune and Inflammatory Disorders Research
  • Elbow and Forearm Trauma Treatment
  • Immunodeficiency and Autoimmune Disorders
  • Musculoskeletal Disorders and Rehabilitation
  • Ocular Diseases and Behçet’s Syndrome
  • Orthopedic Infections and Treatments
  • Shoulder Injury and Treatment
  • Inflammasome and immune disorders
  • Adolescent and Pediatric Healthcare
  • Rheumatoid Arthritis Research and Therapies
  • Hip disorders and treatments
  • Musculoskeletal synovial abnormalities and treatments
  • Salivary Gland Disorders and Functions
  • Salivary Gland Tumors Diagnosis and Treatment
  • Acute Lymphoblastic Leukemia research
  • Organ Donation and Transplantation
  • Neurogenetic and Muscular Disorders Research
  • Infectious Encephalopathies and Encephalitis
  • Renal and Vascular Pathologies
  • Nerve Injury and Rehabilitation
  • Oral Health Pathology and Treatment
  • Kawasaki Disease and Coronary Complications
  • Heterotopic Ossification and Related Conditions
  • Muscle and Compartmental Disorders
  • Lower Extremity Biomechanics and Pathologies

German Center for Pediatric and Adolescent Rheumatology
2013-2024

Garmisch-Partenkirchen Medical Center
2001

Flares of juvenile idiopathic arthritis (JIA) have been described in the context various infections. rheumatic diseases adults following infection with SARS-CoV-2 several cohorts. So far, effect on course JIA is unknown.

10.1186/s12969-021-00653-8 article EN cc-by Pediatric Rheumatology 2021-11-29

Abstract Background Defining of gray scale ultrasound standard reference values the shoulder joint in childhood and adolescence during maturation. Patients: We examined 445 healthy girls boys between 1 year 18 years age. Method A cross-sectional multicentre grey-scale study was performed to examine on both sides. The children were divided according their gender further classified into six age groups, which constituted three-year ranges, record anatomical development changes. measured...

10.1055/s-0043-111596 article EN Klinische Pädiatrie 2017-08-24

Objectives: Chronic anterior uveitis is a serious complication of juvenile idiopathic arthritis (JIA); disease flares are highly associated with loss vision. Leflunomide (LEF) used successfully for JIA joint but its effectiveness in has not been determined. The aim this study was to determine whether LEF improves flare rates patients compared preceding methotrexate (MTX) therapy.Method: A single-centre retrospective consecutive children and chronic performed. All initially received MTX were...

10.3109/03009742.2015.1013983 article EN Scandinavian Journal of Rheumatology 2015-05-20

To identify an optimal pediatric musculoskeletal ultrasound (MSUS) protocol for the detection of knee arthritis in patients with juvenile idiopathic (JIA) including a comparison existing protocols. Secondary aims were to correlate MSUS-identified B-Mode (BM) and Power Doppler-Mode (PD) synovitis clinical findings. Consecutive JIA confirmed after examination underwent thorough MSUS study which included views identified consented by Pediatric Rheumatology european Society (PReS) Imaging...

10.1186/s12969-024-01029-4 article EN cc-by-nc-nd Pediatric Rheumatology 2024-10-21

Abstract Background Juvenile Sjögren’s Syndrome (jSS) is a rare phenomenon that may appear as primary jSS or associated with mixed connective tissue disease (MCTD) and other autoimmune diseases secondary jSS. With currently no standard diagnostic procedures available, in MCTD seems to be underdiagnosed. We intended describe identify similar distinct salivary gland ultrasound (SGUS) findings cohort of patients, focusing on sicca like symptoms glandular pain/swelling the patients‘history....

10.1186/s12969-020-00437-6 article EN cc-by Pediatric Rheumatology 2020-06-09

Hintergrund: Eines der sechs Klassifikationskriterien (nach AECG) für das Sjögrensyndrom (SS) ist ein pathologischer Befund Speicheldrüsen in Szinti- oder Sialografie. In Erwachsenenrheumatologie wird bereits Einsatz Speicheldrüsensonografie gegenüber Sialografie, Szintigrafie und Speichelflussmessung diskutiert. Befunde Daten bei Jugendlichen liegen bislang nicht vor.

10.1055/s-0035-1558799 article DE Ultraschall in der Medizin - European Journal of Ultrasound 2015-07-28

Selective IgA deficiency is the most frequent primary immunodeficiency and associated with an increased rate of respiratory infections in susceptible patients. Juvenile idiopathic arthritis autoimmune disease children affecting joints frequently treated mild to moderately active immunosuppressive medications. We describe a pediatric patient juvenile who developed selective at age 4 years, well-documented prior levels within normal range for that age. This girl was previously diagnosed 2...

10.5455/apr.061820130511 article EN Annals of Paediatric Rheumatology 2013-01-01

<b>Hintergrund:</b> In der deutschen Kinderrheumatologie finden seit etwa 15 Jahren die Gelenksonografie und Magnetresonanztomografie (MRT) zunehmenden Einsatz bei Diagnosestellung einer Juvenilen idiopathischen Arthritis (JIA). <b>Zielsetzung:</b> Ziel unserer Studie war es, sowohl den in kinderrheumatologischen Praxis als auch aktuellen Status Aus- Weiterbildung deutscher Kinderrheumatologen bezüglich bildgebender Verfahren zu erfassen. <b>Methoden:</b> Mitglieder Gesellschaft für Kinder-...

10.1055/s-0035-1555793 article DE Aktuelle Rheumatologie 2015-07-22

<title>Abstract</title> Objectives: To identify an optimal pediatric musculoskeletal ultrasound (MSUS) protocol for the detection of knee arthritis in patients with juvenile idiopathic (JIA) including a comparison existing protocols. Secondary aims were to correlate MSUS-identified B-Mode (BM) and Power Doppler-Mode (PD) synovitis clinical findings. Methods: Consecutive JIA confirmed after examination underwent thorough MSUS study which included views identified consented by rheumatology...

10.21203/rs.3.rs-4724979/v1 preprint EN Research Square (Research Square) 2024-09-18

Pain and impaired function in the shoulder can result from a variety of conditions. Dysplasias girdle are usually asymptomatic; previous literature reports on malformation have focused glenoid dysplasia or complete agenesis clavicle. We report case an 11 year old patient with severe pain after strenuous physical exercise. Physical inspection showed prominent clavicle anteriorly displaced humerus. X-ray demonstrated abnormally shortened hypoplastic acromion; MRI imaging revealed elongated...

10.3941/jrcr.v8i7.1771 article EN cc-by-nc-nd Journal of Radiology Case Reports 2014-07-26

<b>Hintergrund:</b> Bei verschiedenen chromosomalen Störungen wird ein erhöhtes Risiko für eine Juvenile Idiopathische Arthritis (JIA) vermutet. Vor allem bei Patienten mit einem Morbus Down (Trisomie 21) und einer JIA besteht darüber hinaus Unsicherheit bezüglich der geeigneten Therapie DMARDs, weil auch das AML erhöht ist. <b>Methode:</b> In retrospektiven Fall-Kohorte eigener wurde typische Verteilungsmuster die Entzündungsaktivität Trisomie 21 (T21-JIA) sowie deren Ansprechen...

10.1055/s-0042-103746 article DE Aktuelle Rheumatologie 2016-10-13

Chronic anterior uveitis is a common complication of juvenile idiopathic arthritis (JIA). Leflunomide frequently used alternative to methotrexate in the treatment joint manifestations JIA. However, very little known on effect leflunomide concurrent chronic

10.1186/1546-0096-11-s2-p43 article EN cc-by Pediatric Rheumatology 2013-12-01

<h3>Background</h3> Leflunomide is a disease modifying drug (DMARD) used in the treatment of juvenile idiopathic arthritis (JIA). Chronic uveitis frequent complication JIA. Methotrexate and other DMARDS have successfully been this condition. However, few data available effect leflunomide on concurrent chronic <h3>Objectives</h3> To investigate course JIA to determine number flares patients with previous treated leflunomide. <h3>Methods</h3> The database German Center for Pediatric...

10.1136/annrheumdis-2012-eular.1117 article EN Annals of the Rheumatic Diseases 2013-06-01

Zusammenfassung Der Artikel gibt einen Überblick zum aktuellen Stand der Ultraschallbefundung in Kinderrheumatologie und geht insbesondere auf den praktischen Einsatz die technischen Aspekte Gelenksonografie ein. Dabei werden auch wissenschaftlichen Entwicklungen letzten Jahre zusammengefasst berücksichtigt. Neben wird Ultraschalltechnik zunehmend weitere Körperregionen -organe ausgeweitet, für kinderrheumatologische Diagnostik relevant sind.

10.1055/a-1737-3245 article DE Aktuelle Rheumatologie 2022-02-16

<h3>Background</h3> Children with trisomy 21 have an increased risk of developing polyarticular arthritis. Traditionally, these patients receive a diagnosis juvenile idiopathic arthritis (JIA) and are treated accordingly. However, very little data exists regarding presentation treatment response in patients. <h3>Objectives</h3> To determine joint activity distribution pattern JIA their to methotrexate compared seronegative JIA. <h3>Methods</h3> Retrospective case-control study from database...

10.1136/annrheumdis-2015-eular.4838 article EN Annals of the Rheumatic Diseases 2015-06-01

Purpose: Musculoskeletal ultrasound (MSUS) is an important tool for evaluating disease activity, therapeutic progress, and remission status of rheumatic diseases in children. Knowledge age-related normal findings essential when interpreting pathological such as those seen juvenile idiopathic arthritis. The most commonly affected joint childhood arthritis the knee.

10.1055/s-0036-1587723 article EN Ultraschall in der Medizin - European Journal of Ultrasound 2016-08-18

Purpose: In rheumatic diseases a convex shape of the joint capsule is valid as sign effusion. Up to now there are no studies about in healthy childhood population.

10.1055/s-0036-1587726 article EN Ultraschall in der Medizin - European Journal of Ultrasound 2016-08-18

Einleitung: Bei rheumatischen Erkrankungen gilt der sonografische Nachweis einerkonvexen Form Gelenkkapsel als Ausdruck eines durch den Entzundungsprozess bedingten Gelenkergusses. Bisher liegen keine Untersuchungen im Kindes-und Jugendalter vor, die bei gesunden Kindern[zum vollstandigen Text gelangen Sie uber oben angegebene URL]

10.3205/16dgrh072 article DE 2016-01-01
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