Lauren R. Klein

ORCID: 0000-0003-0669-9265
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About
Contact & Profiles
Research Areas
  • Healthcare Decision-Making and Restraints
  • Cardiac Arrest and Resuscitation
  • Airway Management and Intubation Techniques
  • Emergency and Acute Care Studies
  • Restraint-Related Deaths
  • Tracheal and airway disorders
  • Anesthesia and Sedative Agents
  • Intensive Care Unit Cognitive Disorders
  • Poisoning and overdose treatments
  • Appendicitis Diagnosis and Management
  • Psychosomatic Disorders and Their Treatments
  • Foreign Body Medical Cases
  • Respiratory Support and Mechanisms
  • Sepsis Diagnosis and Treatment
  • Trauma and Emergency Care Studies
  • Ethics in medical practice
  • Alcoholism and Thiamine Deficiency
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ultrasound in Clinical Applications
  • Traumatic Brain Injury Research
  • Opioid Use Disorder Treatment
  • Treatment of Major Depression
  • Schizophrenia research and treatment
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Neuroscience of respiration and sleep

Good Samaritan Hospital Medical Center
2021-2025

Hennepin Healthcare Research Institute
2018-2024

University of Washington
2024

Hennepin County Medical Center
2015-2023

Johns Hopkins University
2023

Molloy College
2023

Johns Hopkins Medicine
2023

Moss Landing Marine Laboratories
2023

University of Colorado Anschutz Medical Campus
2022

CHI Health
2021

<h3>Importance</h3> The tracheal tube introducer, known as the bougie, is typically used to aid intubation in poor laryngoscopic views or after attempts fail. effect of routine bougie use on first-attempt success unclear. <h3>Objective</h3> To compare first attempt facilitated by vs endotracheal + stylet. <h3>Design, Setting, and Patients</h3> Bougie Use Emergency Airway Management (BEAM) trial was a randomized clinical conducted from September 2016 through August 2017 emergency department...

10.1001/jama.2018.6496 article EN JAMA 2018-05-17

<h3>Importance</h3> Traumatic brain injury (TBI) is the leading cause of death and disability due to trauma. Early administration tranexamic acid may benefit patients with TBI. <h3>Objective</h3> To determine whether treatment initiated in out-of-hospital setting within 2 hours improves neurologic outcome moderate or severe <h3>Design, Setting, Participants</h3> Multicenter, double-blinded, randomized clinical trial at 20 trauma centers 39 emergency medical services agencies US Canada from...

10.1001/jama.2020.8958 article EN JAMA 2020-09-08

Olanzapine is an atypical antipsychotic with similar pharmacologic properties to droperidol. Due the current droperidol shortage, authors' clinical practice has been substitute olanzapine for in many situations. At this time, U.S. Food and Drug Administration approved oral intramuscular (IM) use only, but due its increased utility, intravenous (IV) was recently study emergency department (ED).The authors sought review safety of IV ED patient population.A retrospective consecutive patients...

10.1111/acem.12842 article EN Academic Emergency Medicine 2015-12-31

Introduction: Case reports and poison center data have demonstrated that the second-generation antipsychotic quetiapine is being obtained utilized for recreational abuse. The purpose of this study was to describe relative rates abuse different atypical antipsychotics, compare their demographic clinical features.Methods: A 10-year retrospective analysis National Poison Data System (NPDS) database conducted (2003 – 2013). Trained nurses pharmacists with specialty training in toxicology...

10.5811/westjem.2016.10.32322 article EN cc-by Western Journal of Emergency Medicine 2017-02-01

Objectives Olanzapine is a second-generation antipsychotic increasingly used in emergency medicine for many indications. Literature on its use children sparse. Our objectives were to describe the use, safety, and efficacy of olanzapine pediatric patients. Methods A structured chart review was performed patients 18 years old or younger receiving from 2007 2016 department level I trauma center. Results total 285 received olanzapine. Mean age 16.4 (range, 9–18 years); 121 male (42.8%). Primary...

10.1097/pec.0000000000001231 article EN Pediatric Emergency Care 2017-07-11

Background Ultrasound has emerged as the preferred initial imaging modality for diagnosing acute appendicitis in children, but most data supporting its use come from academic children's medical centers. The purpose of this investigation is to describe ultrasound utilization children at a large community hospital network. Methods This was multicenter retrospective observational cohort study and chart review pediatric patients with diagnosed emergency department (ED). primary outcome...

10.7759/cureus.82854 article EN Cureus 2025-04-23

Introduction: Research on the effects of 2022 national intravenous iodinated contrast media (ICM) shortage pediatric population in emergency department is limited. The purpose this study was to evaluate patients who had a computed tomography (CT) abdomen/pelvis during ICM shortage, and identify whether any important abdominal diagnoses were missed or if additional CT scans obtained accommodate for lack available ICM. We hypothesized decrease utilization without increased incidence diagnoses....

10.1097/pec.0000000000003391 article EN Pediatric Emergency Care 2025-04-29

Introduction: Food insecurity is a significant issue in the United States and prevalent emergency department (ED) patients. The purpose of this study was to report novel use an integrated electronic medical record (EMR) order for food resources, describe our initial institutional referral patterns after focused education implementation order.Methods: This retrospective, observational study, describing food-bank before dedicated ED on EMR resources. Results: In 2015, prior formal total 1,003...

10.5811/westjem.2017.12.35211 article EN cc-by Western Journal of Emergency Medicine 2018-03-05
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