Young‐Soo Keum

ORCID: 0000-0003-0682-5399
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About
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Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Phytochemicals and Antioxidant Activities
  • Pesticide Residue Analysis and Safety
  • Pesticide and Herbicide Environmental Studies
  • Microbial bioremediation and biosurfactants
  • Insect and Pesticide Research
  • Free Radicals and Antioxidants
  • Toxic Organic Pollutants Impact
  • Algal biology and biofuel production
  • Synthesis and Biological Activity
  • Microbial Metabolic Engineering and Bioproduction
  • Fungal Plant Pathogen Control
  • Fatty Acid Research and Health
  • Berberine and alkaloids research
  • Plant biochemistry and biosynthesis
  • Essential Oils and Antimicrobial Activity
  • Traditional and Medicinal Uses of Annonaceae
  • Synthesis of Organic Compounds
  • Seaweed-derived Bioactive Compounds
  • Synthesis and biological activity
  • Food Quality and Safety Studies
  • Analytical chemistry methods development
  • Moringa oleifera research and applications
  • Retinoids in leukemia and cellular processes
  • Chemical synthesis and alkaloids

Konkuk University
2015-2024

Dongguk University
2014

Konkuk University Medical Center
2014

University of Hawaii System
2003-2013

Seoul National University
2000-2009

Hankyong National University
2007

Korea Institute of Toxicology
2007

Concordia College - Minnesota
2005

Stockholm University
2005

University of Hawaiʻi at Mānoa
2003

Polybrominated diphenyl ethers (PBDEs) are a new class of global, persistent, and toxic contaminants, which need proper remediation technologies. PBDE degradation in the environment is not well understood. In this study, PBDEs with zerovalent iron was investigated six BDEs, substituted one to 10 bromines. Within 40 days 92% BDE congener 209 transformed into lower bromo congeners. During initial reaction period (<5 days), hexa- heptabromo BDEs were most abundant products, but tetra-...

10.1021/es048846g article EN Environmental Science & Technology 2005-02-10

5-Fluorouracil (5-FU) is a widely used anticancer drug for the treatment of colorectal cancer (CRC). However, resistance to 5-FU often prevents success chemotherapy. Nuclear factor-erythroid 2-related factor 2 (Nrf2) transcriptional regulator and possible target overcome resistance. The present study examined epigenetic changes associated with Nrf2 induction in human CRC cell line (SNUC5) resistant (SNUC5/5-FUR). expression, nuclear translocation, binding promoter were higher SNUC5/5-FUR...

10.1038/cddis.2014.149 article EN cc-by Cell Death and Disease 2014-04-17

The ferulic and gallic acid related compounds from natural origin were studied against xanthine oxidase cyclooxygenase-2 along with their anti-inflammatory activity. acid, caffeic p-coumaric revealed promising activity (30–40% TNF-α 60–75% IL-6 inhibitory at 10 μM). Bioavailability of checked by in vitro cytotoxicity using CCK-8 cell lines confirmed to be nontoxic, but found toxic higher concentration (50 Gallic, ferulic, was demonstrated potential dual inhibition toward as calculated IC50:...

10.1016/j.bjp.2015.08.013 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2015-11-29

Nineteen bacterial strains were isolated from petroleum-contaminated soil in Hilo, HI, and characterized by two different spray-plated methods, turbidity test liquid medium, 16S rRNA gene sequence analysis. Analysis of the showed 13 polycyclic aromatic hydrocarbons (PAHs) a range 0.6 to 30 mg/kg dry weight each 12 PAH metabolites. Five distinct (C3, C4, P1-1, JS14, JS19b1) selected preliminary plating tests further tested for degradation through single assay. Strains C3, P1-1 degraded...

10.1021/jf0637630 article EN Journal of Agricultural and Food Chemistry 2007-06-07
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