A5042865371- Shape Memory Alloy Transformations
- Cardiac Valve Diseases and Treatments
- Intermetallics and Advanced Alloy Properties
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrhythmias and Treatments
- Lattice Boltzmann Simulation Studies
- Material Selection and Properties
- Fluid Dynamics Simulations and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Carbon Nanotubes in Composites
- Neuroscience and Neural Engineering
- Titanium Alloys Microstructure and Properties
- Atrial Fibrillation Management and Outcomes
- High-Velocity Impact and Material Behavior
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Paleontology and Evolutionary Biology
- Smart Materials for Construction
- Mechanical Behavior of Composites
- Metal and Thin Film Mechanics
- Fluid Dynamics and Vibration Analysis
- Surface Treatment and Residual Stress
- Bone Tissue Engineering Materials
- Hydrogels: synthesis, properties, applications
- Orthopaedic implants and arthroplasty
Ri.MED
2021-2025
University College London
2021-2022
University of Palermo
2019-2022
A large majority of thrombi causing ischemic complications under atrial fibrillation (AF) originate in the left appendage (LAA), an anatomical structure departing from atrium, characterized by a morphological variability between individuals. This work analyses hemodynamics simulated for different patient-specific models LAA means computational fluid-structure interaction studies, modeling effect changes contractility and shape resulting AF.Three operating conditions were analyzed: sinus...
Fluid-structure interaction (FSI) is required in the study of several cardiovascular engineering problems were mutual between pulsatile blood flow and tissue structures essential to establish biomechanics system. Traditional FSI methods are partitioned approaches where two independent solvers, one for fluid structure, asynchronously coupled. This process results into high computational costs. In this work, a new scheme which avoids coupling different solvers presented framework truly...
Valve-sparing procedures are surgical techniques allowing to restore adequate function of the native aortic valve by replacing dysfunctional ascending aorta with a prosthetic conduit. A number currently used, such as Yacoub's remodelling and David's reimplantation, based on regular straight More recently, De Paulis proposed use bulging conduits reconstruct shape Valsalva sinuses. This work investigates impact valve-sparing technique function.The performance 3 porcine roots (Medtronic...
Biological soft tissues and polymers used in biomedical applications (e.g. the cardiovascular area) are hyperelastic incompressible materials that commonly operate under multi-axial large deformation fields. Their characterisation requires biaxial tensile testing. Due to typically small sample size, gripping of specimens relies on rakes or sutures, where specimen is punctured at edges gauge area. This approach necessitates an apron, excess material around region. work analyses apron...
Thanks to its unique behaviour characterised by a superelastic response, Nitinol has now become the material of preference in number critical applications, especially area medical implants. However, reversible phase transformation producing exceptional comportment is also responsible for phenomena that make mechanical characterisation particularly complex, hindering assumptions at very basis common uniaxial tensile testing. This necessarily reduces level safety and design optimization...
Nickel–Titanium (NiTi) shape memory alloys subjected to cyclic loading exhibit reversible temperature changes whose modulation is correlated with the applied load. This reveals presence of thermomechanical heat sources activated by stresses. One such source elastocaloric effect, accounting for latent Austenite–Martensite phase transformation. It is, however, observed that when amplitude loads not sufficient activate or further propagate this transformation, material still exhibits a strong...
Abstract This paper focuses on the design, fabrication, and characterization of a platform aiming to dynamically culture cells under mechanical stimulation. The platform, made polymethylmethacrylate (PMMA), allows real-time stimuli, providing valuable insights for living tissue models. Through testing dynamic microfluidic tests, chip functionality was assessed. experimental results validation showcases potential device in mimicking physiological conditions, offering promising avenue...
Thanks to its unique behaviour characterised by a superelastic response, Nitinol has now become the material of preference in number critical applications, especially area medical implants. However, reversible phase transformation producing exceptional comportment is also responsible for phenomena that make mechanical characterisation particularly complex, hindering assumptions at very basis common uniaxial tensile testing. This necessarily reduces level safety and design optimization...