A5088297848- Stress Responses and Cortisol
- Heart Rate Variability and Autonomic Control
- Neuroendocrine regulation and behavior
- Psychosomatic Disorders and Their Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Evolutionary Psychology and Human Behavior
- Memory and Neural Mechanisms
- Neural and Behavioral Psychology Studies
- Blood Pressure and Hypertension Studies
- Hormonal Regulation and Hypertension
- Neonatal Respiratory Health Research
- Cardiovascular and exercise physiology
- Olfactory and Sensory Function Studies
- Circadian rhythm and melatonin
- EEG and Brain-Computer Interfaces
- Non-Invasive Vital Sign Monitoring
- Birth, Development, and Health
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychology, Coaching, and Therapy
- Thermoregulation and physiological responses
- Glaucoma and retinal disorders
- Face Recognition and Perception
- Neuroscience of respiration and sleep
- Diabetes Management and Research
- Cardiac Health and Mental Health
Universität Trier
2015-2024
Trier University of Applied Sciences
2019
University of Luxembourg
2015
University Medical Center of the Johannes Gutenberg University Mainz
2015
Johannes Gutenberg University Mainz
2015
Universitätsklinikum Erlangen
2015
University of Basel
1997-2011
Heidelberg University
2000-2010
Foundation for Human Potential
2010
Deutsche Forschungsgemeinschaft
2010
The diagnosis of infection in critically ill patients is challenging because traditional markers are often misleading. For example, serum concentrations calcitonin precursors increased with infections. However, their predictive accuracy for the sepsis unselected a medical intensive care unit (ICU) unknown. Therefore, we compared usefulness precursors, C-reactive protein, interleukin-6, and lactate consecutive suffering from broad range diseases an anticipated stay > or =24 hrs...
Animal studies provided evidence that stress modulates multiple memory systems, favoring caudate nucleus-based "habit" over hippocampus-based "cognitive" memory. However, effects of on learning strategy and consolidation were not differentiated. We specifically address the psychosocial applied in humans. designed a spatial task allowed differentiating from stimulus-response strategies during acquisition. In 13 subsequent trials, participants (88 male female students) had to locate "win" card...
Whether mental performance is affected by slowly progressive moderate dehydration induced water deprivation has not been examined previously. Therefore, objective and subjective cognitive-motor function was in 16 volunteers (8 females, 8 males, mean age: 26 yr) twice, once after 24 h of during normal intake (randomized cross-over design; 7-day interval). Water resulted a 2.6% decrease body weight. Neither estimated paced auditory serial addition task, an adaptive 5-choice reaction time test,...
Abstract Stress and corticosteroid hormones are known to affect learning memory processes. In this study, we examined whether stress corticosteroids capable of facilitating the switch between multiple systems in mice. For purpose, designed a task that allowed measurement nucleus caudate-based stimulus–response hippocampus-based spatial strategies. Naive mice used strategies locate an exit hole on circular board at fixed location flagged by proximal stimulus. When were either stressed or...
Abstract Heart rate variability ( HRV ) is a measure of autonomic influences on heart that has frequently been used as transsituationally consistent biomarker for cardiovascular health and emotional or cognitive functions. The psychometric properties however remain unclear. In the present study, we examined reliability temporal stability parasympathetic measures estimated portion variance explained by trait effects situation person–situation interaction with structural equation modeling....
Human subjects overestimate the change of rising intensity sounds compared with falling sounds. Rising sound has therefore been proposed to be an intrinsic warning cue. In order test this hypothesis, we presented rising, falling, and constant healthy humans gathered psychophysiological behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that facilitates autonomic orienting reflex phasic alertness auditory targets. produced...
Core features of depersonalization/derealization disorder (DPD) are emotional numbing and feelings disembodiment. Although there several neurophysiological findings supporting subjective numbing, the psychobiology disembodiment remains unclear.Heartbeat-evoked potentials (HEPs), which considered psychophysiological indicators for cortical representation afferent signals originating from cardiovascular system, were assessed in 23 patients with DPD 24 healthy control individuals during rest...
Objective A number of sympathetic nervous system (SNS) parameters have been used in cardiovascular psychophysiology. This study aimed to describe the pattern and redundancy a set SNS during peripherally induced changes cardiac activation reflex modulation central control. Preejection period (PEP) was assessed as marker peripheral activation. Low-frequency blood pressure variability (BPV) an estimate Methods Peripheral β-sympathetic stimulation blockade were achieved with epinephrine esmolol...
Disembodiment is a core feature of depersonalization disorder (DPD). Given the narratives DPD patients about their disembodiment and emotional numbing neurobiological findings an inhibition insular activity, may be considered as mental with specific impairments interoceptive awareness body perception.We investigated cardioceptive accuracy (CA) (n=24) compared to healthy controls (n=26) two different heartbeat detection tasks ("Schandry counting task" "Whitehead discrimination task")....
Abstract Insulin and cortisol play a key role in the regulation of energy homeostasis, appetite, satiety. Little is known about action interaction both hormones brain structures controlling food intake processing neurovisceral signals from gastrointestinal tract. In this study, we assessed impact single combined application insulin on resting regional cerebral blood flow (rCBF) insular cortex. After standardized periods restriction, 48 male volunteers were randomly assigned to receive either...
Parental divorce has been associated with reduced well-being in young adults. It is, however, unclear whether this finding is clinically relevant as studies using structured clinical interviews are missing. This study, therefore, investigated if adults divorced parents at risk to develop mental disorders. Furthermore, differences parental care, social connectedness, chronic stress and traumatic experiences between children of non-divorced were investigated. 121 women (mean age: 23 years)...
Early life adversity (ELA) may cause permanent disturbances in brain-body signaling. These are thought to contribute physical symptoms and emotional dysregulation adulthood. The current study investigated the effects of childhood trauma on young adults' interoceptive accuracy as an indicator communication that be dysregulated by ELA. Sixty-six participants completed online questionnaire followed a laboratory session including socially evaluated cold pressor stress test during which ECG,...