Testicular dysfunction or damage is among the critical side effects of chemotherapeutic drugs like cisplatin. This study was mapped out to assess possible therapeutic effect eugenol on cisplatin-induced testicular damage. In this experimental study, a single dose cisplatin (15 mg/kg) given intraperitoneally. After 72 hr injection, rats were sacrificed and testis tissues removed. Tissues examined by biochemical, histopathological immunohistochemical methods. While tissue lipid peroxidation...

<title>Abstract</title> In this study, it was aimed to determine the efficacy of radiotherapy using different vibration spectroscopy techniques before (BR) and after (AR) blood serum samples from patients with Non-Small Cell Lung Cancer (NSCLC). The study performed on 20 who received a total dose 6600 cGy radiotherapy. Principal Component Analysis (PCA) Hierarchical Clustering (HCA) methods were used as Unsupervised Pattern detect inter-sample variations in AR BR spectra. Support Vector...

Abstract In this study, serum carnitine (CRNT) and adiponectin (APN) levels the correlation of these parameters in patients with breast cancer before after treatment radiotherapy (RT) were determined. Materials methods Serum assessed 58 carcinoma 30 control subjects. APN determined using a specific enzyme-linked immunosorbent assay. Results While level was significantly lower RT compared group (p=0.002 p=0.019, respectively), higher than ( p=0.003 p=0.027, respectively). Carnitine showed...

Objective The purpose of this study was to employ biochemical, histopathological, and immunohistochemical methods reveal the effectiveness hesperidin thymol in preventing radiotherapy‐associated submandibular gland injury. Methods A total 48 female Sprague Dawley rats were randomly assigned into six groups eight animals each. Group 1 represented control group. 2 regarded as Group, received only hesperidin. 3 thymol. 4 a Radiotherapy exposed radiotherapy at dose 15 Gy. 5 + 100 mg/kg daily for...

Abstract In this study, we sought to determine how well naringenin, hesperidin, and quercetin prevented damage brought on by radiotherapy. During the investigation, 48 adult female Sprague Dawley rats were used. Eight groups of eight each formed randomly assigning groups. The normal control group was represented Group 1. 2 those that received a dose 15 Gray (Gy) assigned 3 only Naringenin, whereas 4 quercetine, 5 hesperidin. Rats in 6, 7 8 quarcetin hesperidin at 50 mg/kg daily for one week...

The aim of this study was to determine whether plasma lecithin:cholesterol acyltransferase (pLCAT) and erythrocyte membrane Na(+)-K(+)-ATPase ase (emNaKATPs) activity have a correlation in breast cancer. This compared these parameters at time points before after treatment with radiotherapy.The levels pLCAT emNaKATPs were assessed 30 patients carcinoma 20 control subjects. While measured spectrophotometric method, using specific enzyme-linked immunosorbent assay.pLCAT levels, both...

It is believed that radiotherapy has important effects on oxidant/antioxidant systems. Oxidative stress occurs when the balance between oxidant formation and antioxidant defense disrupted in favor of oxidants. The aim this study was to determine biochemical changes saliva pre- postradiotherapy head-neck patients find out radiation glutathione (GSH), peroxidase (GSH-Px), malondialdehyde (MDA) levels saliva.This included 16 undergoing Atatürk University Research Hospital. GSH, GSH-Px, MDA were...

Objective The study aimed to assess the level of knowledge patients with cervical cancer referred radiation oncology outpatient clinics in Turkey regarding screening methods and human papillomavirus (HPV) vaccination increase social awareness based on findings. Methods A descriptive cross-sectional survey was conducted from January June 2022 involving 300 various regions. Data demographics, HPV knowledge, recommendations relatives were collected through a questionnaire-based interview....

To evaluate the results of postoperative chemoradiotherapy in patients with gastric cancer. Gastric cancer is an important public health problem Turkey, especially eastern Anatolia region. Surgery primary modality for managing early-stage disease, but most who undergo a curative resection develop locoregional or distant recurrence. Therefore, administration adjuvant treatment has great importance. Materials and methods: Operated stage IB-IV (M0) were enrolled this study. A total 148 had...

Treatment planning is primarily based on the tumor node metastasis (TNM) staging system for head and neck cancer (HNC). However, TNM does not give sufficient information about biological aggressiveness, treatment response, prognosis. New molecular markers are needed individualized treatment. Apelin a bioactive peptide an endogenous ligand G protein-coupled receptor (APJ). Its expression induced under hypoxic conditions. its APJ important factors in physiological angiogenesis may be novel...

Isolated lymphoma of the base tongue is a relatively rare condition. The clinical presentation may vary from submucosal mass with cystic appearance to an ulcerated lesion. In present case, was identified in patient admitted sore throat. Pathological examination confirmed diffuse large B-cell lymphoma. and pathological picture lymphomas covers wide spectrum rate occurrence oral cavity 3-5%. Among all malignant tumors cavity, represent third most common type tumor, following squamous cell...

The present study investigated the dimensional changes in submandibular glands following radiotherapy using ultrasonography.Twenty-three patients planned to receive head-neck were included this study. anteroposterior, superoinferior, mediolateral length, and volumes of 46 measured by ultrasonography at 3 different time periods (before second sixth months after onset) evaluated terms effect radiation dose on these changes. data statistically analyzed repeated measures analysis variance...

Objective The functions of E-selectin, interleukin (IL)-23, and soluble intercellular adhesion molecule (sICAM) in patients with non-small cell lung cancer (NSCLC) before after radiotherapy (RT) are poorly understood. purpose our study was to investigate serum IL-23, E-selectin sICAM levels NSCLC RT. Methods Forty-four pathologically confirmed 30 healthy individuals were included the study. All received 66.6 Gy concurrent Results Significant differences observed between controls both...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Radiotherapy affects salivary glands more intensely than it does other organs, and gland dysfunction can continue during or after treatment. The aim of this study was to examine structural alterations in submandibular through ultrasonography following head-neck radiotherapy patients evaluate the impact radiation dose on these modifications. Forty-six were assessed ultrasonographically for changes echogenicity, echotexture, margin influence before at 3 time points: second sixth months...

Aim: The purpose of this study was to investigate MPV and RDW values in DTC patients. Background: Differentiated Thyroid Cancer (DTC) is subdivided into papillary, follicular papillary micro thyroid cancers. Mean Platelet Volume (MPV) red cell distribution width (RDW) are markers which have been investigated many cancers, but no data available for DTC. Objective: were assessed 108 patients with DTC, consisting 44 Papillary (PTC) (mean age 43±13.9 years), 34 Micro (PmTC) 43.1 ± 10.6), 28...

Prediction of tumor volume using the Cavalieri method may be helpful in management therapy and evaluation treatment results. The aim this study was to adapt stereological magnetic resonance imaging for determining nasopharyngeal cancers assess changes after method. Serial MRI images sagittal plane were obtained from a total 33 patients with carcinomas (11 stage T2, 11 T3, T4 lesions). analyzed retrospectively before two months following cessation radiochemotherapy comparison. Average volumes...

ABSTRACT Introduction: Thyroid cancers are the most common malignant tumors of endocrine origin. They classified depending on their histopathological and clinical behaviors. Papillary follicular as differentiated thyroid carcinomas (DTCs). The neutrophil/lymphocyte ratio (NLR) monocyte to high-density lipoprotein cholesterol (MHR) have recently been shown be powerful markers oxidative stress systemic inflammation, MHR has revealed a potent marker mortality in coronary heart disease...

ÖzAmaç: Baş ve boyun kanserlerinin tedavisinde radyoterapi önemli rol oynar.Bununla birlikte, küratif tedavide mukozit ağız kuruluğu en sık görülen yan etkilerdir.Bu prospektif, randomize çalışmanın amacı, baş kanserli hastalarda radyasyon kaynaklı tükürük bezi hasarının önlenmesinde çinko sülfat amifostinin etkinliğini kantitatif sintigrafisi (QSGS

This study investigated pre- and post-treatment tumor lymph node dimension response rates differences between side-effect profiles in patients with locally advanced inoperable nonsmall-cell lung cancer (NSCLC) receiving radiotherapy (RT) concurrent chemotherapy (CT).A total of 30 who had not previously received RT having a mean age 58.73±8.65 years sufficient hematological reserves normal hepatic renal functions were included the study. Those pleural effusion, supraventricular metastasis, N3...