Hyesun Park

ORCID: 0000-0003-0707-1875
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Lung Cancer Research Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Intimate Partner and Family Violence
  • Lung Cancer Diagnosis and Treatment
  • Injury Epidemiology and Prevention
  • Cancer-related molecular mechanisms research
  • Health and Wellbeing Research
  • Peptidase Inhibition and Analysis
  • Trauma and Emergency Care Studies
  • Medical Imaging Techniques and Applications
  • Diet and metabolism studies
  • Sexual Assault and Victimization Studies
  • Metabolism and Genetic Disorders
  • Cancer survivorship and care
  • Elder Abuse and Neglect
  • Radiopharmaceutical Chemistry and Applications
  • Homicide, Infanticide, and Child Abuse
  • Ovarian cancer diagnosis and treatment
  • Thyroid Cancer Diagnosis and Treatment
  • Human-Automation Interaction and Safety
  • CAR-T cell therapy research

Brigham and Women's Hospital
2018-2025

Dana-Farber Brigham Cancer Center
2019-2024

Dana-Farber Cancer Institute
2018-2024

Lahey Hospital and Medical Center
2022-2024

Harvard University
2018-2024

Catholic University of Korea
2013-2023

Seoul St. Mary's Hospital
2023

Lahey Medical Center
2023

Chung-Ang University
2020-2022

Chungnam National University
2016-2021

Thermal ablation using radiofrequency is a new, minimally invasive modality employed as an alternative to surgery in patients with benign thyroid nodules and recurrent cancers.The Task Force Committee of the Korean Society Thyroid Radiology (KSThR) developed recommendations for optimal use tumors 2012.As new meaningful evidences have accumulated, KSThR decided revise guidelines.The revised guideline based on comprehensive analysis current literature expert consensus.

10.3348/kjr.2018.19.4.632 article EN Korean Journal of Radiology 2018-01-01

Background Intimate partner violence (IPV) is a global social and public health problem, but published literature regarding the exacerbation of physical IPV during coronavirus disease 2019 (COVID-19) pandemic lacking. Purpose To assess incidence, patterns, severity injuries in victims COVID-19 2020 compared with prior 3 years. Materials Methods The demographics, clinical presentation, injuries, radiologic findings patients reporting abuse arising from statewide between March 11 May 3, 2020,...

10.1148/radiol.2020202866 article EN other-oa Radiology 2020-08-13

<h3>BACKGROUND AND PURPOSE:</h3> Contrast-enhanced CT protocols for papillary thyroid cancer are yet to be optimized. Our aim was compare the diagnostic accuracy of arterial phase and delayed-phase lateral cervical lymph node metastasis from carcinoma by using tissue attenuation. <h3>MATERIALS METHODS:</h3> This retrospective study included 327 nodes (177 metastatic 150 benign) 131 patients with (107 initially diagnosed 24 recurrences). Patients underwent 1 3 protocols: a 70-second (A) or...

10.3174/ajnr.a5054 article EN cc-by American Journal of Neuroradiology 2017-01-26

Abstract Purpose: ATM is the most commonly mutated DNA damage and repair gene in non–small cell lung cancer (NSCLC); however, limited characterization has been pursued. Experimental Design: Clinicopathologic, genomic, treatment data were collected for 5,172 patients with NSCLC tumors which underwent genomic profiling. IHC was performed on 182 NSCLCs mutations. Multiplexed immunofluorescence a subset of 535 samples to examine tumor-infiltrating immune subsets. Results: A total 562 deleterious...

10.1158/1078-0432.ccr-22-3413 article EN Clinical Cancer Research 2023-04-25

Although real-time cell electronic sensing (RT-CES) system-based natural killer (NK) cytotoxicity has been introduced, it not evaluated using human blood samples. In present study, we measured flowcytometry based assay (FCA) and RT-CES NK analyzed degranulation activity (CD107a) cytokine production. 98 healthy individuals, FCA with peripheral mononuclear cells (PBMCs) at effector to target (E/T) ratio of 32 revealed 46.5 ± 2.6% cytolysis K562 cells, 23.5 1.1% showed increased degranulation....

10.1155/2013/210726 article EN BioMed Research International 2013-01-01

While most patients with follicular lymphoma (FL) have excellent outcomes frontline chemoimmunotherapy (CIT), a subset of will experience early progression, which is associated poor subsequent outcomes. Novel biomarkers are needed to identify high-risk earlier. We hypothesized that interim positron emission tomography (PET) would predict progression-free survival (PFS) in this population. retrospectively identified 128 grade 1–3A FL who had an PET after 2–4 cycles CIT at 2 academic centers....

10.1097/hs9.0000000000000826 article EN cc-by-nc-nd HemaSphere 2023-01-24

The objective of this study was to compare the effects supplementation with two methionine isoforms, L-methionine (L-Met) or D-methionine (D-Met), on transcriptome expression in broiler chickens under acute heat stress. A total 240 one-day-old chicks were randomly assigned one four treatments a 2 × factorial arrangement: thermo-neutral vs. heat-stress and L-Met D-Met supplementation. On day 14, heat-stressed group exposed 32°C for 5 h, while others remained at 25°C. Six selected per...

10.1371/journal.pone.0246063 article EN cc-by PLoS ONE 2021-01-27

Improved biomarkers are required to guide the optimal use of autologous stem cell transplantation (ASCT) in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). We hypothesized that minimal residual disease (MRD) identified using immunoglobulin high-throughput sequencing apheresis (ASC) samples, post-ASCT peripheral blood mononuclear (PBMC), and plasma samples could predict relapse. studied 159 R/R DLBCL who underwent ASCT, whom 98 had an ASC sample 60 surveillance...

10.1182/bloodadvances.2022007706 article EN cc-by-nc-nd Blood Advances 2022-11-18
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