- Natural product bioactivities and synthesis
- Chemical synthesis and alkaloids
- Alkaloids: synthesis and pharmacology
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Biological Activities
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Botanical Research and Chemistry
- Plant Toxicity and Pharmacological Properties
- Traditional and Medicinal Uses of Annonaceae
- Steroid Chemistry and Biochemistry
- Plant-based Medicinal Research
- Phytochemicals and Medicinal Plants
- Analytical Chemistry and Chromatography
- Pharmacogenetics and Drug Metabolism
- Plant biochemistry and biosynthesis
- Cancer Treatment and Pharmacology
- NMR spectroscopy and applications
- Advanced NMR Techniques and Applications
- Sesquiterpenes and Asteraceae Studies
- Bioactive natural compounds
- Phytochemical Studies and Bioactivities
- Synthesis and biological activity
- Computational Drug Discovery Methods
- Molecular spectroscopy and chirality
Islamia College University
2025
Technion – Israel Institute of Technology
2025
University of Karachi
2015-2024
International Center for Chemical and Biological Sciences
2015-2024
University of Peshawar
2008-2024
University of Cambridge
2013-2024
Khyber Medical College
2019-2024
King's College Hospital
2012-2024
Anhui Polytechnic University
2023-2024
Duke University
2024
The incidence of 2019 novel corona virus (SARS-CoV-2) has created a medical emergency throughout the world. Various efforts have been made to develop vaccine or effective treatments against disease. discovery crystal structure SARS-CoV-2 main protease in silico identification its inhibitors possible. Based on critical role viral replication, can prove be promising "target" for antiviral drug therapy. We systematically screened an in-house library 15,754 natural and synthetic compounds,...
Nigellidine (1), only the second example of a natural product containing an indazole nucleus, was isolated from Nigella sativa and characterized by spectroscopic X-ray diffraction techniques.
Abstract In piezoceramics, the Curie temperature ( T C ) and piezoelectric coefficient d 33 are often inversely proportional, so it is very difficult to optimize high piezoelectricity simultaneously. addition, temperature‐insensitive strain * with small hysteresis also a longstanding obstacle in development of lead‐free ceramics. this work, facile approach donor doping strategy adopted replace Ba 2+ Yb 3+ , Y Sm Nd as result, 450 °C outstanding 422–436 pC N −1 achieved by novel magnetic...
Abstract The plant kingdom offers a rich source of structural biodiversity in the form variety natural products. Our work on new bioactive compounds from medicinal plants has led to isolation and structure elucidation number exciting pharmacophores. Bioassay-guided fractionation recently discovery series acetylcholinesterase, urease a-glucosidase inhibitors, antioxidants other classes compounds, which will be presented. A theory based hydrogen bonding chemical basis memory storage brain is
Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined basis extensive spectroscopic studies including 2D-NMR experiments.
Iris plants have immense medicinal importance and are therefore used in the treatment of cancer, inflammation, bacterial viral infections (Nadkarni, 1976). Gas chromatography-mass spectrometry analysis petroleum ether extract (oil) plant resulted identification eleven compounds, 9-hexadecanoic acid methyl ester, 9-octadecenoic 8-octadecenoic 11-octadecenoic methyl, 10-octadecenoic 13-octadecenoic 16-octadecenoic 1,2-benzenedicarboxylic diisooctyl bis (2-ethylhexyl) phthalate, 6-methyl...