A5059605597- Genomics and Phylogenetic Studies
- Algal biology and biofuel production
- Microbial Metabolic Engineering and Bioproduction
- Genetics, Aging, and Longevity in Model Organisms
- Conducting polymers and applications
- Electrochemical sensors and biosensors
- Plant Gene Expression Analysis
- CRISPR and Genetic Engineering
- Plant biochemistry and biosynthesis
- Biofuel production and bioconversion
- Microbial Community Ecology and Physiology
- Phytochemicals and Antioxidant Activities
- Chromosomal and Genetic Variations
- Plant Molecular Biology Research
- Gene Regulatory Network Analysis
- Genetic diversity and population structure
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Photosynthetic Processes and Mechanisms
- Enzyme Production and Characterization
- Marine Bivalve and Aquaculture Studies
- Marine and coastal plant biology
- Gold and Silver Nanoparticles Synthesis and Applications
- Aquatic Invertebrate Ecology and Behavior
- Advanced biosensing and bioanalysis techniques
- Protist diversity and phylogeny
Fujian Normal University
2013-2025
Sichuan University
2025
Fujian Medical University
2020-2024
Fujian Institute of Oceanography
2021-2024
Soochow University
2019-2024
First Affiliated Hospital of Soochow University
2022-2024
Sun Yat-sen University
2019-2024
Shanghai Changzheng Hospital
2024
Anhui Agricultural University
2024
Third Affiliated Hospital of Sun Yat-sen University
2024
Doxorubicin (DOX) as a traditional chemotherapy drug is restricted in clinical applications due to its poor therapeutic activity and severe side effects. Herein, we prepared metal-organic framework (MOF) MIL-100 by microwave-assisted synthesis DOX was loaded then, hyaluronic acid (HA) modified on the surface of give DMH NPs. The NPs possessed following advantages: (1) could serve carrier with high loading efficiency; also generate hydroxyl radical (˙OH) presence H2O2 for chemodynamic therapy...
Goldfish have been subjected to over 1,000 y of intensive domestication and selective breeding. In this report, we describe a high-quality goldfish genome (2n = 100), anchoring 95.75% contigs into 50 pseudochromosomes. Comparative genomics enabled us disentangle the two subgenomes that resulted from an ancient hybridization event. Resequencing 185 representative variants 16 wild crucian carp revealed origin identified genomic regions shaped by sweeps linked its domestication. Our...
Abstract Cerebral palsy is the most prevalent physical disability in children; however, its inherent molecular mechanisms remain unclear. In present study, we performed in-depth clinical and analysis on 120 idiopathic cerebral families, identified underlying detrimental genetic variants 45% of these patients. addition to germline variants, found disease-related postzygotic mutations ∼6.7% We that patients with more severe motor impairments or a comorbidity intellectual had significantly...
The karyotype of most birds has remained considerably stable during more than 100 million years' evolution, except for some groups, such as parrots. evolutionary processes and underlying genetic mechanism chromosomal rearrangements in parrots, however, are poorly understood. Here, using chromosome-level assemblies four parrot genomes, we uncover frequent chromosome fusions fissions, with them occurring independently among lineages. increased activities parrots likely associated...
The slow-evolving invertebrate amphioxus has an irreplaceable role in advancing our understanding of the vertebrate origin and innovations. Here we resolve nearly complete chromosomal genomes three species, one which best recapitulates 17 chordate ancestor linkage groups. We reconstruct fusions, retention, or rearrangements between descendants whole-genome duplications, gave rise to extant microchromosomes likely existed ancestor. Similar vertebrates, genome gradually establishes its...
In this study, renewable tea waste hydrolysate was used as a sole carbon source for carotenoids and lipid production. A novel
Problem: The pandemic requires the expanded use of technology and implementation innovative strategies to improve online learning experience. We aim explore an pedagogy that exposes learners a realistic clinical scenario stimulates active student engagement bridge patient care scientific inquiry.Approach: converted sessions continuing medical education with emphasis on problem case study skill training in 2022 new blended based metaverse where we applied modified TBL utilizing strengths PBL...
Pharmacognosy Magazine,2015,11,43,449-454.DOI:10.4103/0973-1296.160447Published:July 2015Type:Original ArticleAuthors:Yusi Zhang, Ting Lv, Min Li, Xue, Hui Liu, Weiming Xiaoyu Ding, and Ziheng Zhuang Author(s) affiliations:Yusi Zhang1, Lv1, Li2, Xue2, Liu2, Ding1, Zhuang1 1 College of Life Sciences, Nanjing Normal University, Nanjing, 210046, China 2 School Pharmaceutical Engineering Changzhou Changzhou, 213164, Abstract:Background: Polysaccharide isolated from Bletilla striata, a well known...
Detection of circulating tumor cells (CTCs) may be applied for diagnosis early tumors like a liquid biopsy. However, the sensitivity remains challenge because CTCs are extremely rare in peripheral blood. In this study, we developed supersensitive CTC analysis system based on triangular silver nanoprisms (AgNPR) and superparamagnetic iron oxide nanoparticles (SPION) with function capture, enrichment, detection, release. The AgNPR was encoded MBA (i.e., 4-mercaptobenzoic acid) modified rBSA...
Empty follicle syndrome (EFS) is a condition in which no oocyte retrieved from mature follicles after proper ovarian stimulation an vitro fertilization procedure. Genetic evidence accumulates for the etiology of recurrent EFS without pharmacological or iatrogenic problems. In this study, we present two infertile sisters family with three cycles standard human chorionic gonadotrophin and/or gonadotropin-releasing hormone agonist therapy. Via whole-exome sequencing and cosegregation test,...
Abstract Salvia bowleyana is a traditional Chinese medicinal plant that source of nutritional supplements rich in salvianolic acid B and potential experimental system for the exploration biosynthesis Labiatae. Here, we report high‐quality chromosome‐scale genome assembly S. covering 462.44 Mb, with scaffold N50 value 57.96 Mb 44,044 annotated protein‐coding genes. Evolutionary analysis revealed an estimated divergence time between its close relative miltiorrhiza ~3.94 million years. We also...
Abstract Isochrysis galbana is considered an ideal bait for functional foods and nutraceuticals of humans because its high fucoxanthin (Fx) content. However, multi-omics analysis the regulatory networks Fx biosynthesis in I. has not been reported. In this study, we report a high-quality genome assembly LG007, which size 92.73 Mb, with contig N50 6.99 Mb 14,900 protein-coding genes. Phylogenetic confirmed monophyly Haptophyta, sister to Emiliania huxleyi Chrysochromulina tobinii. Evolutionary...