- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Retinal Imaging and Analysis
- Systemic Lupus Erythematosus Research
- Innovations in Medical Education
- Ocular Infections and Treatments
- Dental Research and COVID-19
- Diagnosis and Treatment of Venous Diseases
- Entomological Studies and Ecology
- Health Education and Validation
- Hematological disorders and diagnostics
- Glaucoma and retinal disorders
- Dermatological and Skeletal Disorders
- Drug-Induced Ocular Toxicity
- Ocular Disorders and Treatments
- Cellular transport and secretion
- Retinopathy of Prematurity Studies
- Vasculitis and related conditions
- Intraocular Surgery and Lenses
- Peripheral Neuropathies and Disorders
- Ocular Oncology and Treatments
- Online and Blended Learning
- Neonatal and fetal brain pathology
- Retinal and Macular Surgery
Amrita Institute of Medical Sciences and Research Centre
2015-2025
Amrita Vishwa Vidyapeetham
2020-2023
Creative Commons
2021
Lamar University
2015
Tamil University
1980
To determine the relationship between diabetic retinopathy (DR) and peripheral neuropathy (DPN), their associated risk factors.
We report a case of coexisting proliferative diabetic retinopathy (PDR) and macular telangiectasia (MacTel) with neovascularization type 3. A 50-year-old patient presented decrease in the RE vision. Her presenting vision was 20/80 LE 20/30. She diagnosed both eye PDR features MacTel eyes such as right-angled vein pigment migration. On fundus examination, there presence atypical large PEDs RE, which warranted multimodal imaging. SDOCT revealed trapezoid serous PED along erosion sign...
Purpose: The purpose of this study is to evaluate the clinical profile, visual, anatomical and survival outcome patients with endogenous endophthalmitis. Methods: Retrospective chart review consecutive cases endophthalmitis presenting from 2009-2016. Results: In our study, 41 eyes 34 were included. Most common co-morbidity associated was Diabetes Mellitus (70.7%) most infective foci UTI (73.2%). Among culture positive cases, fungi bacteria evenly distributed, 76.93% Gram 23.07% negative....
Purpose: To study the incidence and risk factors of raised intraocular pressures (IOPs) in follow-up transconjunctival sutureless vitrectomy (TSV). Methods: A retrospective observational was performed on 635 patients who underwent TSV under a single surgeon. The IOPs were recorded using calibrated non-contact tonometer at seven postoperative visits, viz., day 1, 7 3, 6 months, 1 month following silicone oil removal. Results: IOP rise seen 24.25% (154) out eyes studied. Among 50 years age,...
The family of Tre2-Bub2-Cdc16 (TBC)-domain containing GTPase activating proteins (RABGAPs) is not only known as key regulatorof RAB activity but also has GAP-independent functions. Rab GTPases are implicated in membrane trafficking pathways, such vesicular trafficking. We report biallelic loss-of-function variants TBC1D2B, encoding a member the TBC/RABGAP with yet unknown function, underlying cause cognitive impairment, seizures, and/or gingival overgrowth three individuals from unrelated...
The study aimed to evaluate comparability in terms of efficacy, safety and immunogenicity Sun's ranibizumab biosimilar with reference patients neovascular age-related macular degeneration (nAMD). This prospective, randomised, double-blind, two-group, parallel-arm, multicentre, phase 3 comparative included nAMD ≥ 50 years, randomised (in a 2:1 ratio) double-blind manner receive 0.5 mg (0.05 mL) intravitreal injection either or the eye every 4 weeks until week 16 (total four doses). Primary...
Introduction: Subglottic stenosis is a condition leading to narrowing of subglottal space due intubation, inflammation, tracheostomy, trauma, and idiopathic conditions.Respiratory effort the patient increases this narrowing.The effect also perceived in speech production as effortful exhalation, unnatural pause shallow breathing, muscle tension.Surgical treatment including cricoplasty tracheal anastomosis can improve respiratory function but adversely affect voice production, especially adult...
Purpose: Identification of nonresponders prior to anti-vascular endothelial growth factor (anti-VEGF) therapy would help in the judicious clinical management diabetic macular edema (DME) patients. Thus, a systematic study was initiated identify nonresponding DME patient population undergoing ranibizumab treatment figure out additional inflammatory components that may contribute their nonresponsiveness anti-VEGF therapy. Methods: A total 40 patients recruited this investigator-initiated trial...
The present article reviews various evolutionary events that resulted in skin color variation among humans. Skin of the early man is presumed to be colorless as chimpanzees. During course evolution, hairless state with sweat glands would have occurred for purpose thermoregulation. Thermoregulation was very important brain development and function. In due course, pigmentation naked order offer photo-protection. physiological demand vitamin D<sub> 3</sub> folate human system effect sun-light...
Background: The COVID-19 pandemic situation has forced a shift in medical education from physical classroom to virtual online teaching. However, students and teachers perceive this differently. It is important study these perceptions improve the teaching–learning process, thus validate role of learning country. Objective: To document process pilot for questionnaire-based regarding perception undergraduate towards on-going classes. Methods: Medical Education Department teaching hospital...
Abstract GM2 Gangliosidoses are a group of autosomal recessive genetic disorders caused by intra-lysosomal deposition ganglioside mainly in the neuronal cells. GM2-Activator protein deficiency is an extremely rare type gangliosidosis (AB variant) mutation GM2A.We report case female child who presented with clinical features similar to classical Tay-Sachs disease, but normal beta hexosaminidase enzyme levels. Molecular study revealed novel homozygous intronic which confirmed diagnosis...
Retinopathy of prematurity (ROP) is a vasoproliferative disease that affects premature infants. ROP on rise in India as result the improved neonatal care and better survival rate. Identifying screening at-risk infants performed by an experienced ophthalmologist remains most important strategy management ROP. In developing countries, introduction Retcam-assisted enables follow-up rural population where may not be available. Currently, laser photocoagulation avascular retina has replaced...
Medical education is going through a new learning experience of its own due to the impossibility physical classes in present pandemic situation. This article describes detail conceptualization and development questionnaire for specific purpose studying perception undergraduate students medical college toward online program.
Our primary aim was to evaluate intraocular cytokines (IC) before and after dexamethasone in diabetic macular edema (DME). secondary study the early late effects of single implant DME.This comparative conducted at Department Ophthalmology Centre for Nanosciences a quaternary referral center Kerala, India, from September 2016 2018. Patients underwent complete ophthalmological examination cytokine analysis implant. Levels baseline repeat sample were studied.Twenty-seven eyes (21 patients)...
Background The Covid-19 pandemic drastically affected medical education. One consequence was the shift of teaching–learning process to online mode. This left many teachers unprepared. Our education department a large teaching hospital did qualitative analysis perceptions faculty towards this forced change. Methods We conducted in-depth interviews with 10 nearly hundred undergraduate in southern India, strength 100 students per batch. participants were chosen by purposive sampling so as...
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease that mainly involves the optic nerve and spinal cord. Purpose of this case series to better understand clinical profile patients with NMOSD, its treatment, prognosis differentiate them from having other demyelinating disorders. Five (one male four females) aged between 18 65 years were studied. All presented severe vision loss. Bilateral involvement was seen in unilateral one patient. One patient only involvement, two...
To evaluate visual outcome and complications of PDR after treatment with Intravitreal Bevacizumab followed by Pan Retinal Photocoagulation A hospital based retrospective study was done in the Department Ophthalmology, to intravitreal Photocoagulation. Visual Acuity, Dilated fundus examination, OCT macula were on subsequent follow ups 135 eyes 133 patients included study.The mean pre procedure acuity is 0.639±0.5327 which improved 0.451±0.4089 post procedure. P value &#60;0.001...
1. To analyse the visual outcome in patients of paediatric uveitis who underwent cataract surgery; 2. post-operative complications surgery uveitis. Retrospective observational study was done on surgery. Patients were under 18 years and co-operative for examination included. They Phacoaspiration with posterior chamber IOL implantation by a single surgeon after 3 months activity free interval, BCVA(in Log MAR) every follow up, anterior segment using slit lamp IDO, Intra ocular pressure...
Radiation maculopathy, a subset of significant radiation retinopathy, is one the most common causes visual loss following localized, regional, or whole-brain radiotherapy. Ozurdex (Allergan Inc., Irvine, CA, USA), sustained-release intravitreal implant 0.7 mg dexamethasone, has been used as an off-label treatment for treating recalcitrant maculopathy. However, to best our knowledge, beneficial effect dexamethasone in contralateral eye patient with maculopathy not described literature so far....