A5101652934- Stroke Rehabilitation and Recovery
- 3D IC and TSV technologies
- Electronic Packaging and Soldering Technologies
- Acute Ischemic Stroke Management
- Glaucoma and retinal disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Musculoskeletal pain and rehabilitation
- Cerebral Palsy and Movement Disorders
- Nanofabrication and Lithography Techniques
- Copper Interconnects and Reliability
- Ocular Surface and Contact Lens
- Alzheimer's disease research and treatments
- Advanced Drug Delivery Systems
- Image Processing and 3D Reconstruction
- Industrial Vision Systems and Defect Detection
- Cardiac Arrhythmias and Treatments
- Biliary and Gastrointestinal Fistulas
- Neurology and Historical Studies
- Advancements in Photolithography Techniques
- Esophageal and GI Pathology
- Traumatic Brain Injury Research
- Synthesis and properties of polymers
- Prostate Cancer Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Healthcare and Venom Research
UCLA Health
2018-2025
University of California, Los Angeles
2012-2023
HCA Healthcare
2023
Peking University First Hospital
2018
Peking University
2018
Cedars-Sinai Medical Center
2017
Advanced Micro Devices (Canada)
2009-2016
Advanced Micro Devices (United States)
2016
Olive View-UCLA Medical Center
2015
VA Greater Los Angeles Healthcare System
2015
In recent years, the 2.5D IC (Integrated Circuit) package with TSV (Through Silicon Vias) has become important for high-bandwidth and high-performance applications. It is well known that technology requires significant innovation in areas of process technology, packaging, design, thermals, test solutions leading to several hundred new technologies a single product. With these complex material sets steps combined design requirements, methods, components, amount research engineering...
Enhanced neural plasticity early after stroke suggests the potential to improve outcomes with intensive rehabilitation therapy. Most patients do not get such therapy, however, due limited access, changing therapy settings, low doses, and poor compliance.To examine feasibility, safety, efficacy of an established telerehabilitation (TR) program initiated during admission inpatient facility (IRF) completed in patient's home.Participants hemiparetic admitted IRF received daily TR targeting arm...
Background: Early-onset Alzheimer’s disease (EOAD) has been overshadowed by the more common late-onset AD (LOAD). Yet, literature indicates EOAD may have less hippocampal-memory presentations and focal neocortical localization early in disease. Objective: To evaluate these proposed differences between 2 forms of to explore what they inform about pathophysiology. Methods: In all, 21 patients with 24 LOAD matched for progression severity were compared on neurocognitive measures resting state...
Purpose: To evaluate the effect of decreasing topical cyclosporine 0.05% (tCSA) (Restasis; Allergan, Irvine, CA) from twice-daily dosing to once-daily in patients who have already completed 12 months therapy for dry eye disease. Design: Prospective, randomized, single-masked, parallel group comparison. Participants: One hundred had been treated with tCSA twice daily more than 1 year were randomized either continue (n = 50) or decrease once 50). Methods: Clinical measurement variables was...
Introduction: Restorative therapies have maximal impact when introduced early post-stroke. Dopamine modulates learning and plasticity, its levels decrease after stroke, making it a key therapeutic candidate. For restorative therapy to promote experience-dependent concomitant training is needed must be provided experimentally given low rehabilitation doses received with usual care (UC); here this was using an established telerehabilitation (TR) system. Current hypotheses : [H1] Adding...
High density I/O (Input/Output) with close proximity communication between dies in 2.5D heterogeneous integration of disparate ICs (Integrated Circuits) requires substantially miniaturized interconnect. Micro-bump consists down sized Cu pillar and solder is the chosen interconnect technology for die stacking volume manufacturing. The bump height shortened to less than 20µm due significantly reduced diameter. In order achieve high manufacturing yield long term reliability micro-bump joint, a...
Proprioception is critical to motor control and functional status but has received limited study early after stroke. Patients admitted an inpatient rehabilitation facility for stroke (n = 18, mean(±SD) 12.5 ± 6.6 days from stroke) older healthy controls 19) completed the Wrist Position Sense Test (WPST), a validated, quantitative measure of wrist proprioception, as well cognitive testing. were serially tested when available 12, mean 11 between assessments). In controls, WPST error was 9.7...
This paper, based on an excellent keynote address by AMD's Jeff Rearick at 3D-TEST 2015, describes the design and test development of one world's first high-volume 3-D die stacks hence a landmark product: Fury GPU.
The introduction of low-k/ultra-low-k (ULK) dielectric materials to accommodate the continuous scaling-down feature sizes IC chips improve device density and performance ultra-large scale integrated (ULSI) circuits represents great silicon packaging integration challenges due weak mechanical properties interlayer material (ILD). Implementation crackstop low-k/ULK are very effective protect ILD crack propagation delamination. Finite element analysis (FEA) simulation Shadow Moire measurements...
The introduction of low-k/ultra-low-k (ULK) dielectric materials to accommodate the continuous scaling down feature sizes IC chips improve device density and performance ultra-large scale integrated (ULSI) circuits represents great silicon packaging integration challenges due weak mechanical properties. To CPI reliability Cu/low-k or ULK devices, a new crackstop design has been introduced. Underfill selection, layer effect, interfacial strength improvement low-k/ULK films, lead-free impact...
Ultrathin silicon chips are becoming more and popular because of market demand for small, light, high- performance products with noticeable request reliability flexibility. In this paper, the flexibility Integrated Circuit package is investigated using finite-element (FE) analysis. ANSYS software used to analyze a single ultrathin die in smart card under four-point bending aim developing flexible modules thickness below 50 mum. Thicknesses different layers Young's modulus adhesive...
Abstract Background Many stroke recovery interventions are most beneficial when started 2-14d post-stroke, a time patients become eligible for inpatient rehabilitation facilities (IRF) and neuroplasticity is often at its peak. Clinical trials focused on need to expand the from this plasticity later outcome timepoints. Methods The disability course of with acute ischemic (AIS) intracranial hemorrhage (ICH) enrolled in Field Administration Stroke Therapy Magnesium (FAST-MAG) Trial...
Cognitive deficits can impact functional outcomes as well the efficacy of rehabilitation therapy after stroke, but these must be understood in context specific cognitive impairments. We describe here improvement during admission to an inpatient facility (IRF) a patient with uncommon form abnormality, Alice Wonderland Syndrome (AIWS), which is characterized by visual and other perceptual distortions. The course this syndrome has not been previously described. A 52-year-old male acute ischemic...
Neurology, as an independent medical specialty, is a relatively young field, originally stemming from internal medicine and psychiatry. The roots of neurology in Taiwan are no different. Modern was established the 1950s. Prior to that, neurologic diseases were uncommon mainly consisted infectious CNS. 1950s brought on establishment dedicated clinics primary training at various sites Taiwan.1 expansion these continued flourish over next several decades. Neurology further developed with...
This paper studied the effects of polyimide surface morphology and RIE treatment for lead-free C4 bumping SOI device on assembly process by flip-chip technique. The characterizations were experimentally carried out with FTIR, AFM CSAM. sequences have been optimized based DOE results.
Background: Tele-stroke has been an efficient cost-effective way to standardize care and improve access immediate neurologic for rural hospitals other areas underserved by neurologists. Virtual telestroke support is commonly used in the Emergency Department. Hands-free wearable technology allows seamless communication faster more informed decisions. It can advance triage of stroke patients into pre-hospital setting at scene or ambulance facilitate routing comprehensive centers. Objective: To...
OBJECTIVE: To determine the effects of early post traumatic seizures (EPTS) on outcomes in a pediatric population.
Background: Proprioception is critical to motor control. The prevalence, severity, and clinical correlates of deficits in wrist proprioception early after stroke have received limited attention were examined patients admitted an inpatient rehabilitation facility (IRF). Methods: Patients for our IRF (n=18) older healthy controls (n=12) completed the Wrist Position Sense Test (WPST), a validated, quantitative measure, as well cognitive testing. serially tested when available (n=12). Results:...