A5079594830- Lignin and Wood Chemistry
- Enzyme-mediated dye degradation
- Biochemical and biochemical processes
- Plant Gene Expression Analysis
- COVID-19 and healthcare impacts
- Fermentation and Sensory Analysis
- Astro and Planetary Science
- Biofuel production and bioconversion
- 3D Printing in Biomedical Research
- Aortic Disease and Treatment Approaches
- Healthcare cost, quality, practices
- Advanced Cellulose Research Studies
- Microbial bioremediation and biosurfactants
- Climate Change and Health Impacts
- Planetary Science and Exploration
- COVID-19 Clinical Research Studies
- Isotope Analysis in Ecology
- Wood Treatment and Properties
- Enzyme Catalysis and Immobilization
- Cardiac Ischemia and Reperfusion
- Circadian rhythm and melatonin
- IgG4-Related and Inflammatory Diseases
- Tissue Engineering and Regenerative Medicine
- Ion Channels and Receptors
- Infectious Aortic and Vascular Conditions
Kyoto University
1984-2023
Keio University
2016-2018
Kyoto Pharmaceutical University
2017
Hiroshima University
2015-2016
Kinan Hospital
2000-2015
Osaka National Hospital
2010-2013
Osaka University
2008
Kyoto Bunkyo University
1972-1988
Gifu University
1967
Neurovascular unit (NVU) is a basic in the brain, including neurons, glial cells, blood vessels and extracellular matrix. This concept implies importance of three-dimensional (3D) culture model these cell types for investigating brain functions. However, little known about construction an vitro 3D NVU model. In present study, we aimed at constructing neurovascular tissues by combining neurogenesis angiogenesis models using microfluidic platform, which critical step toward vitro. Three gel...
In response to the coronavirus diseases 2019 (COVID-19) pandemic, Japanese government declared a state of emergency on April 7, 2020. Six days earlier, Japan Surgical Society had recommended postponing elective surgical procedures. Along with growing public fear COVID-19, hospital visits in decreased. Using claims data from Quality Indicator/Improvement Project (QIP) database, this study aimed clarify impact first wave considered be March May 2020, case volume and claimed charges acute care...
Oxidation of veratryl alcohol by lignin peroxidase (LiP) was potently inhibited oxalic acid. The inhibition analysis with Lineweaver-Burk plots clearly showed that the type is non-competitive. enzymatic oxidation in presence 14C-oxalic acid yielded radioactive carbon dioxide. results indicate apparent LiP caused reduction cation radical intermediate back to substrate level oxalate, which concomitantly oxidized
A biologically active lipid, sphingosine-1-phosphate (S1P) is highly abundant in blood, and plays an important role regulating the growth, survival, migration of many cells. Binding endogenous ligand S1P results activation various signaling pathways via G protein-coupled receptors, some which generates Ca2+ mobilization. In astrocytes, reported to evoke signaling, proliferation, migration; however, precise mechanisms underlying such responses astrocytes remain be elucidated. Transient...
Abstract Aims The Coronavirus Disease 2019 (COVID‐19) pandemic has had unprecedented effects on health care utilization for acute cardiovascular diseases. Although hospitalizations coronary syndrome decreased during the COVID‐19 pandemic, there is a paucity of data trends and management heart failure (HF) cases. Furthermore, concerns have been raised that angiotensin‐converting enzyme inhibitors (ACEIs) angiotensin receptor blockers (ARBs) may increase susceptibility to COVID‐19. This study...
Aim: The coronavirus disease 2019 (COVID-19) pandemic has left negative spillover effects on the entire health care system. Previous studies have suggested significant declines in cases of acute coronary syndrome (ACS) and primary percutaneous intervention (PCI) during COVID-19 pandemic.
Article Biomimetic Approach to Lignin Degradation II. The Mechanism of Oxidative C—C Bond Cleavage Reactions Model Compounds with Natural Iron (III) Porphyrin Chloride as a Heme-Enzyme System was published on January 1, 1987 in the journal Holzforschung (volume 41, issue 5).
Enzymatic oxidation of veratryl alcohol yielded a new ring cleavage product (δ‐lactone) in addition to the two known γ‐lactone products. The experiment with 18 O‐enriched water and dioxygen clearly showed that one oxygen atom each from is specifically incorporated into at original C 3 or 4 position 3,4‐dimethoxybenzyl alcohol. A type reaction mechanism proposed for this compound rationally explained good accord one‐electron transfer mechanism.
Article Dehydrogenative Polymerization of Monolignols by Peroxidase and H2O2 in a Dialysis Tube. II. Estimation Molecular Weights Thermal Softening Method was published on January 1, 1982 the journal Holzforschung (volume 36, issue 3).
A non‐phenolic β‐ O ‐4 lignin substructure model compound, 1,3‐dihydroxy‐2‐(2‐methoxyphenoxy)‐1‐(4‐ethoxy‐3‐methoxyphenyl)propane, was degraded by streptomyces cyaneus in liquid shaken cultures. 4‐Ethoxy‐3‐methoxybenzoic acid could be identified TLC and GC/MS as the main product, indicating cleavage of CαCβ bond aryl glycerol‐β‐aryl ether. In addition, 4‐ethoxy‐3‐methoxybenzaldehyde guaiacol were culture extracts further degradation products.
Since the outbreak of coronavirus disease 2019 (COVID-19) pandemic, guidance ("Japanese Guide") has been published by a working group several academic societies and announced Ministry Health, Labour, Welfare. Steroids as candidate treatment for COVID-19 were noted in Japanese Guide. However, prescription details steroids, whether Guide changed its clinical practice, unclear. This study aimed to examine impact on trends steroids inpatients Japan. We selected our population using Diagnostic...
Abstract When wood was treated with 23% aqueous sodium hydroxide followed by washing water and drying, no lattice conversion of cellulose observed under the experimental conditions employed. On other hand, subjected to a pretreatment that results in loosening its morphological texture, upon mercerization, showed varying degree conversion. The explosion process TFA (trifluoroacetic acid) treatment were used achieve texture. studied X-ray diffractograms. extent found depend on increased an...
It is known that the Sayama meteorite (CM2) shows an extensive signature for aqueous alteration on parent body, and most of primary minerals in chondrules are replaced with phyllosilicates as result alteration. In this paper, it confirmed from observation two-dimensional Raman spectra a part olivine chondrule collected chondrite serperntinized. Ion microprobe analysis showed alkaline elements such Rb Cs heterogeneously redistributed chondrule. The higher contents serpentinized phases rather...