A5023989259- Spine and Intervertebral Disc Pathology
- Bone Tissue Engineering Materials
- Orthopaedic implants and arthroplasty
- Magnesium Alloys: Properties and Applications
- Immune Cell Function and Interaction
- Medical Imaging and Analysis
- Cervical and Thoracic Myelopathy
- Peptidase Inhibition and Analysis
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Immune cells in cancer
- Spinal Fractures and Fixation Techniques
- Electrospun Nanofibers in Biomedical Applications
- Luminescence and Fluorescent Materials
- Phagocytosis and Immune Regulation
- Cancer-related molecular mechanisms research
- Cellular and Composite Structures
Second Affiliated Hospital of Jilin University
2023-2025
Wuhan University
2025
Zhongnan Hospital of Wuhan University
2025
Union Hospital
2022
Jilin University
2022
ABSTRACT Hepatectomy is a critical treatment for liver cancer, but achieving complete tumor removal remains challenging. The development of tumor‐targeting probes capable accurately identifying locations and providing real‐time intraoperative navigation significant clinical importance. We synthesize tumor‐targeted probe by conjugating fibroblast activation protein inhibitor (FAPI) with near‐infrared organic room temperature phosphorescence (RTP) material. then analyze its surgical...
Abstract CpG oligodeoxynucleotides (CpG), as an immunoadjuvant, can facilitate the transformation of tumor‐associated macrophages (TAMs)into tumoricidal M1 macrophages. However, accumulation free in tumor tissues remains a substantial challenge. To address this, nanovaccine (PLGA‐CpG@ID8‐M) is engineered by encapsulating within PLGA using ID8 ovarian cancer cell membranes (ID8‐M). This demonstrates remarkable efficacy reprogramming TAMs and significantly extends survival ID8‐bearing mice....
In anterior cervical discectomy and fusion (ACDF), an interbody device is essential implant. An unsuitable can cause postoperative complications, including subsidence nonunion. We designed a customized intervertebral to reduce complications validated it by finite element analysis. Herein, we built non-homogeneous model of the C3-7 spine. Three implant models (customized cage, commercial bone graft cage) were constructed placed in C45 segment after ACDF surgery. The simulated range motion...
Transforaminal endoscopic spine system resection of upper articular process with different proportions often has effects on lumbar biomechanics. Therefore, finite element method was used to explore this problem in study. The Finite Element (FE) model constructed and validated study a 3D heterogeneous the L1-S1 spine. Nine groups models resect were compared six physiological movements. Following experiment, we reached following main results. peak Von Mises stress left L5 increased most...