A five-component model of schizophrenia has been presented by Kay and Sevy based upon an analysis the Positive Negative Syndrome Scale. found factorial validity for negative positive syndromes, they identified excitement, depressive, cognitive components as well. They suggested that subtypes syndromes can be mapped along dimensions in their model. The present study compares solution a new sample 146 subjects to reanalysis data. Despite divergent demographic characteristics, two samples...

<h3>Background</h3> Cognitive deficits are a major determinant of social and occupational dysfunction in schizophrenia. In this study, we determined whether neurocognitive enhancement therapy (NET) combination with work (WT) would improve performance on neuropsychological tests related to but different from the training tasks. <h3>Methods</h3> Sixty-five patients schizophrenia or schizoaffective disorder were randomly assigned NET plus WT alone. Neurocognitive included computer-based...

To investigate cognitive variables related to affect recognition in schizophrenia, 63 subjects with DSM-III-R diagnoses of schizophrenia or schizoaffective disorder were administered a test battery which included the Bell-Lysaker Emotion Recognition Task (BLERT), Wisconsin Card Sorting Test (WCST), Wechsler Memory (WMS-R) and Adult Intelligence Scales (WAIS-R), Hopkins Verbal Learning Test, Gorham's Proverbs, Continuous Performance (CPT). Coefficients revealed moderate relationship between...

In a psychiatric rehabilitation study, 154 concurrent ratings were performed using the 30-item Positive and Negative Syndrome Scale (PANSS) 18-item Brief Psychiatric Rating (BPRS). Although both instruments had excellent interrater reliability, PANSS was consistently better: on 18 symptom items two share, higher intraclass r's 14; for syndromes, than BPRS positive, negative, total. Weighted Kappas comparing shared revealed that most not interchangeable, with only three coefficients in range....

This study had three aims: to compare a schizophrenia sample (n = 50) with substance abuse 25) and normal 81) on affect recognition; differences in their performance between positive negative introduce new videotape method of stimulus presentation. Subjects were asked identify the predominant depicted 21 5–10-s vignettes containing trials seven states. Results demonstrate significant group differences: subjects scored or mild range, (s/a) moderate ranges, predominantly severe ranges....

The purpose of this study was to explore the relationship between Theory Mind (ToM) performance and schizophrenia subtype, symptom, neuropsychological variables. One hundred twenty-eight stable outpatients with or schizoaffective disorder were assessed during intake phase a vocational cognitive rehabilitation study. Results indicate that ToM differed significantly by diagnosis, people diagnosed disorganized performing most poorly. also correlated measures thought verbal memory. Regression...

Social cognition has been suggested to be an important mediating variable in the relationship between neurocognition and functional outcome. The present study tested this model relation work rehabilitation outcome added self-reported social discomfort as a possible mediator. One hundred fifty-one participants with schizophrenia or schizoaffective disorder participated 26-week therapy program. Neurocognition was constructed latent construct comprised of selected variables from our intake test...

Although indirect support can be found for the clinical benefits of work, it has not been studied in randomized designs, nor have critical variables manipulated. One such variable is pay incentive. The authors present a study 150 subjects with schizophrenia or schizoaffective disorder who were into Pay ($3.40/hour) and No-Pay conditions offered 6-month work placements within Department Veterans Affairs medical center. Subjects participated work-related group evaluated weekly on symptom...

Factor analysis of the Bell Object Relations Inventory items produced four subscales interpreted to be underlying dimensions object relations. Replication factor confirmed structure. Subscales had high internal consistency and were free age, sex, or social desirability response bias. low intercorrelations with Brief Psychiatric Rating Scale (BPRS) sum scores, Global Assessment most BPRS symptoms. appear represent common features personality sample a domain that is distinct from...

Over the recent years there has been a growing debate regarding extent and nature of overlap in neuropathology between schizophrenia (SZ) autism spectrum disorder (ASD). Dynamic functional network connectivity (dFNC) is analysis method that explores temporal patterns (FC). We compared resting-state dFNC SZ, ASD healthy controls (HC), characterized associations symptoms, performed three-way classification based on indices.Resting-state fMRI was collected from 100 young adults: 33 ASD, 34 HC....

Adherence to treatment in psychiatric populations is notoriously low. In this randomized, controlled, proof-of-concept study, we sought examine whether motivational interviewing (MI) could be used enhance motivation for, adherence to, and benefit obtained from cognitive rehabilitation. Dual diagnosis MI, developed specifically for individuals with psychotic symptoms disorganization, was further adapted focus on impairments their impact. Sixty-four outpatients diagnosed schizophrenia spectrum...

Cognitive impairments may be an important contributor to disability in schizophrenia and limit the rate of improvement work rehabilitation. Thirty-three outpatients with or schizoaffective disorder who participated a 6-month rehabilitation program were assessed for symptom severity administered neuropsychological testing at intake. Their performance was evaluated biweekly using Work Behavior Inventory. On each five domains performance, 76 91 percent subjects reached proficiency improved...

Cognitive symptoms of schizophrenia may represent a separate component the disorder that is distinct from positive or negative syndromes. In previous study, we reported factor analysis Positive and Negative Syndrome Scale (PANSS) revealed five components, one which labeled component. present explored validity PANSS by examining correlations between neuropsychological measures factor-analytically derived scores for 147 subjects with diagnoses schizoaffective disorder. Higher on were...

Objective: To determine whether augmenting work therapy (WT) with neurocognitive enhancement (NET) yields greater improvement in working memory performance than WT alone and there is an interaction severity of impairment. Method: A total 102 participants schizophrenia or schizoaffective disorder were categorized as severely less cognitively impaired randomly assigned to receive NET + alone. consisted cognitive training exercises attention, memory, executive function, social information...

Research has linked impaired insight in schizophrenia to poorer medication compliance and treatment outcome. It is unclear, however, whether interpersonal function also associated with insight. To examine this question, subjects or schizoaffective disorder were classified as having unimpaired (N = 44) 57) insight, their scores on Heinrichs et al.'s Quality of Life (QOL) Scale compared. Multiple regressions conducted determine the relationship between individual components social function....

Patients with schizophrenia have long been observed to perform poorly on the Wisconsin Card Sorting Test (WCST). Although numerous studies established links between WCST performance and specific diffuse structural brain abnormalities, little is known about its relationship occupational functioning. The present study has investigated behavior at a vocational work placement test for 89 subjects or schizoaffective disorder. Multiple regression analyses that examined select raw scores covaried...