Nanofibers are able to form a highly porous mesh and their large surface-to-volume ratio improves performance for many applications. Electrospinning has the unique ability produce nanofibers of different materials in various fibrous assemblies. The relatively high production rate simplicity setup makes electrospinning attractive both academia industry. A variety can be made applications energy storage, healthcare, biotechnology, environmental engineering, defense security.

Electrospun collagen-blended poly(L-lactic acid)-co-poly(∈-caprolactone) [P(LLA-CL), 70:30] nanofiber may have great potential application in tissue engineering because it mimicks the extracellular matrix (ECM) both morphologically and chemically. Blended nanofibers with various weight ratios of polymer to collagen were fabricated by electrospinning. The appearance blended was investigated scanning electron microscopy transmission microscopy. exhibited a smooth surface narrow diameter...

Fabrication of nanofibrous scaffolds with well-defined architecture mimicking native extracellular matrix analog has significant potentials for many specific tissue engineering and organs regeneration applications. The fabrication aligned collagen by electrospinning was described in this study. structure vitro properties these were compared a random scaffold. All the first crosslinked glutaraldehyde vapor to enhance biostability keep initial nano-scale dimension intact. From culture rabbit...

Progress in the electrospinning techniques has brought new methods for production and construction of various nanofibrous assemblies. The parameters affecting include electrical charges on emerging jet, charge density removal, as well effects external perturbations. solvent method fiber collection also affect final architecture. Various yarn spinning using solid liquid surfaces surface-free are described compared this review. Recent advances allow 3D scaffolds with a desired microstructure....

Despite recent advances in electrospinning, creating highly ordered structure through the use of electrospun fibres is not possible. This due to chaotic motion electrospinning jet which means that deposition location covers a few centimetres radius. As result, applications for are restricted where precise positioning required. However, steel blades control electric field, it now possible create fibre bundle made aligned nanofibres ends fixed during electrospinning. The creation structures...

Electrospinning offers an avenue to produce small diameter tubes made out of nanofibres. However, date, most from electrospun fibres have been either random or sheets that were rolled into tubes. Although there suggestions getting circumferentially aligned fibres, this is the first time a method used create tube diagonally has described. This was formed by depositing on rotating during electrospinning give resultant with uniform thickness and superior all round mechanical strength without...

The development of blended collagen and glycosaminoglycan (GAG) scaffolds can potentially be used in many soft tissue engineering applications since the mimic structure biological function native extracellular matrix (ECM). In this study, we were able to obtain novel nanofibrous collagen-GAG by electrospinning with chondroitin sulfate (CS), a widely GAG, mixed solvent trifluoroethanol water. electrospun scaffold 4% CS (COLL-CS-04) exhibited uniform fiber nanoscale diameters. A second 10%...

Abstract Quick establishment of a confluent and stable endothelial cells (ECs) layer in the lumen vascular grafts is critical for long‐term patency small‐diameter grafts. The objective study was to fabricate tubular nanofiber scaffolds, incorporate ECs onto establish an animal model prove basic concept using scaffolds as Poly( L ‐lactic acid)‐ co ‐poly(ε‐caprolactone) P(LLA‐CL 70:30) were fabricated by electrospinning rotating mandrel. Collagen coated after air plasma treatment. Structure...

A novel nanofibrous construct for promoting peripheral nerve repair was fabricated and tested in a rat sciatic defect model. The conduit is made out of bilayered membranes with the nanofibers longitudinally aligned lumen randomly oriented on outer surface. intra-luminal guidance channel yarns. In addition, biomolecules such as laminin growth factor were incorporated to determine their efficacy vivo regeneration. Muscle reinnervation, withdrawal reflex latency, histological, axon density...

Abstract A new technology based on the liquid support system is introduced for fabricating continuous twisted nanofibrous yarn. In this novel technique, electrospun yarn was collected from top of water vortex such that it can be simultaneously during production. Our study demonstrated feasibility technique producing well aligned nanofibers. It shown modified to have different counts with various twists. Further, significant improvement seen in strength and strain when compared non‐twisted...

In this paper, various three-dimensional (3D) nanofibrous structures were constructed based on liquid support systems and alteration of the solution charge property. Structures fabricated from system include a ring spindle-shaped ones. The ease fabricating fluffy, randomly organized structure by altering capacity electrospun is also demonstrated. set-up conditions for design using these techniques are discussed.

An implantable scaffold pre-seeded with cells needs to remain viable and encourage rapid angiogenesis in order replace injured tissues, especially for tissue defect repairs. We created a bioartificial adipose graft composed of an electrospun 3D nanofibrous fat excised from New Zealand white rabbits. Cell viability potential the substitute were examined during four weeks culture Dulbecco's Modified Eagle Medium by immunohistochemical staining LIVE/DEAD® cell kit PECAM-1 antibody,...

Introduction: A covered stent is one whose length and circumference enclosed with a membrane or fabric like material. Current stents have been used in the treatment of failed saphenous vein grafts coronary bypass artery perforations. Covered also proposed treating brain aneurysm. However, none these applications showed satisfactory results. The deficiencies are 1) Large wall thickness 2) Rigidity 3) Non-biodegradable polymer poor endothelialization. Materials methods: Aligned...