- Characterization and Applications of Magnetic Nanoparticles
- Geomagnetism and Paleomagnetism Studies
- Microfluidic and Bio-sensing Technologies
- Advanced MRI Techniques and Applications
- Transportation and Mobility Innovations
- Magnetic properties of thin films
- Cardiovascular Health and Disease Prevention
- Urban Transport and Accessibility
- Atomic and Subatomic Physics Research
- Transportation Planning and Optimization
- Electrical and Bioimpedance Tomography
- Minerals Flotation and Separation Techniques
- Human Mobility and Location-Based Analysis
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Aortic aneurysm repair treatments
- Hematological disorders and diagnostics
- Vascular Procedures and Complications
- Magnetic Field Sensors Techniques
- Clinical Laboratory Practices and Quality Control
- Central Venous Catheters and Hemodialysis
- Cardiac Imaging and Diagnostics
- Biosensors and Analytical Detection
- Renal and Vascular Pathologies
- NMR spectroscopy and applications
University of Würzburg
2016-2025
Universitätsklinikum Würzburg
2017-2022
Technical University of Applied Sciences Würzburg-Schweinfurt
2012-2018
Technische Universität Braunschweig
2010-2017
University of Groningen
2017
MRB Research Center for Magnetic Resonance Bavaria
2014-2016
Motiva (Finland)
2010
Sutter Institute for Medical Research
2004-2005
Sutter Medical Center
2001
In this paper we analyze extensive operational data from bike-sharing systems in order to derive bike activity patterns. A common issue observed is imbalances the distribution of bikes. We use Data Mining gain insight into complex patterns at stations. Activity reveal bikes and lead a better understanding system structure. structured process supports planning operating decisions for design management systems.
Minimally invasive endovascular interventions have become an important tool for the treatment of cardiovascular diseases such as ischemic heart disease, peripheral artery and stroke. X-ray fluoroscopy digital subtraction angiography are used to precisely guide these procedures, but they associated with radiation exposure patients clinical staff. Magnetic Particle Imaging (MPI) is emerging imaging technology using time-varying magnetic fields combined nanoparticle tracers fast highly...
Most 3-D magnetic particle imaging (MPI) scanners currently use permanent magnets to create the strong gradient field required for high resolution MPI. However, using limits of view (FOV) due large amount energy move free point (FFP) from center scanner. To address this issue, an alternative approach called "Traveling Wave MPI" is here presented. This employs a novel system, dynamic linear array, cover FOV while dynamically creating gradient. The proposed design also enables so-called...
Abstract Background Magnetic particle imaging (MPI) allows for radiation-free visualization of tracers without background signal. With the first human-sized interventional MPI scanner being recently developed, aim present study was to test its performance guiding endovascular procedures in a realistic perfusion model. Methods Three fresh-frozen cadaveric legs were prepared establish continuous circulation superficial femoral artery via introducer sheaths inguinal and infragenicular region....
While magnetic particle imaging (MPI) constitutes a novel biomedical technique for tracking superparamagnetic nanoparticles in vivo, unlike resonance (MRI), it cannot provide anatomical background information. Until now these two modalities have been performed separate scanners and image co-registration has hampered by the need to reposition sample both systems as similarly possible. This paper presents bimodal MPI-MRI-tomograph that combines single system.MPI MRI images can thus be acquired...
Magnetic particle imaging (MPI) is a non-invasive modality for direct detection of superparamagnetic iron-oxide nanoparticles based on the nonlinear magnetization response magnetic materials to alternating fields. This highly sensitive and rapid method allows both quantitative qualitative analysis measured signal. Since first publication MPI in 2005 several different scanner concepts have been presented 2009 vivo results beating mouse heart were shown. However, since field view (FOV)...
Abstract Magnetic Particle Imaging (MPI) is a promising new tomographic modality for fast as well three-dimensional visualization of magnetic material. For anatomical or structural information an additional imaging such computed tomography (CT) required. In this paper, the first hybrid MPI-CT scanner multimodal providing simultaneous data acquisition presented.
Purpose:To assess the feasibility of magnetic particle imaging (MPI) to guide stenting in a phantom model. Materials and Methods: MPI is new tomographic method based on background-free field detection tracer agent composed superparamagnetic iron oxide nanoparticles (SPIOs). All experiments were conducted custom-built scanner (field view: 29-mm diameter, 65-mm length; isotropic spatial resolution 1–1.5-mm). Stenosis phantoms (n=3) consisted polyvinyl chloride (PVC) tubes (8-mm inner diameter)...
Abstract Magnetic nanoparticles (MNPs) have been adapted for many applications, e.g., bioassays the detection of biomarkers such as antibodies, by controlled engineering specific surface properties. Specific measurement binding states is high interest but currently limited to highly sensitive techniques ELISA or flow cytometry, which are relatively inflexible, difficult handle, expensive and time-consuming. Here we report a method named COMPASS ( C ritical- O ffset- M agnetic- Pa rticle- S...
Tens of thousands web applications are written in Flask, a Python-based framework. Despite rich ecosystem extensions, there is none that supports the developer gaining insight into evolving performance their service. In this paper, we introduce Flask Dashboard, library addresses problem. We present ease with which can be integrated an already existing application, discuss some visualization perspectives provides and point to future challenges for similar libraries.
Magnetic Particle Imaging (MPI) is a fast imaging technique to visualize the distribution of superparamagnetic iron-oxide nanoparticles (SPIONs). For spatial encoding, field free area moved rapidly through view (FOV) generating localized signal. Fast moving samples, e.g., bolus SPIONs traveling large veins in human body carried by blood flow with velocities order ~45 cm/s, cause temporal blurring MPI measurements using common sequences and reconstruction techniques. This hampers evaluation...
Magnetic particle imaging (MPI) is a promising new tomographic method to detect the spatial distribution of superparamagnetic iron-oxide nanoparticles (SPIOs). The aim this paper was investigate potential MPI quantify artificial stenoses in vessel phantoms. Custom-made stenosis phantoms (length 40 mm; inner diameter 8 mm) with different degrees (0%, 25%, 50%, 75%, and 100%) were scanned custom-built scanner (in-plane resolution: ~1-1.5 mm field view: 65 29 mm3). Phantoms filled diluted...
Magnetic particle imaging (MPI) is a novel tomographic method, which allows determining the distribution of superparamagnetic iron-oxide nanoparticles in three dimensions. So far, various MPI systems have been presented with each one emphasizing different scanner features such as large field view (FOV) or high resolution. For both resolution and FOV, optimization harmonization hardware parameters well tracer material are key prerequisites. The traveling wave (TWMPI) approach uses an array...
Since the first publication in 2005, several different scanner types for magnetic particle imaging (MPI) have been presented. One of these concepts is traveling wave MPI (TWMPI). It uses a dynamic linear gradient array, which generates and moves field free point with strong gradient, necessary scanning sample 3-D. Due to properties TWMPI device, very fast 2-D frame rates higher than 1500 frames/s possible (superspeed mode). Using superspeed mode high speed measurements are conceivable, e.g.,...
Since the introduction of magnetic particle imaging in 2005, several different types scanner were presented. One them is traveling wave (TWMPI) scanner. It uses for a dynamic linear gradient array generation strong and field free point. An unresolved issue TWMPI approach so far non-isotropic spatial resolution. As an alternative this paper, rotating slice scanning mode presented to overcome issue. This rotates scanning-slices around axis projection reconstruction method get 3-D volume with...
Adaptive streaming is fast becoming the most widely used method for video delivery to end users over internet. The ITU-T P.1203 standard first standardized quality of experience model audiovisual HTTP-based adaptive streaming. This recommendation has been trained and validated H.264 resolutions up including full-HD. paper provides an extension existing short-term mode 0 new codecs i.e., H.265, VP9 AV1 larger than full-HD (e.g. UHD-1). based on two subjective tests. In tests, in total 13...