A5043208701- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Health Systems, Economic Evaluations, Quality of Life
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Healthcare Policy and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Ultrasound in Clinical Applications
- Disaster Response and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Meta-analysis and systematic reviews
- Primary Care and Health Outcomes
- Nursing Roles and Practices
- Pneumonia and Respiratory Infections
- Healthcare cost, quality, practices
- Heart Failure Treatment and Management
- Patient Satisfaction in Healthcare
- Epilepsy research and treatment
- Diagnosis and Treatment of Venous Diseases
- COVID-19 and healthcare impacts
- Healthcare Systems and Technology
University of Sheffield
2016-2025
Northern General Hospital
2001-2025
Sheffield Teaching Hospitals NHS Foundation Trust
2006-2025
Queen Mary University of London
2020-2024
Guy's and St Thomas' NHS Foundation Trust
2024
ORCID
2024
Comenius University Bratislava
2023
Western University
2023
National Kinki Chuo Hospital for Chest Disease
2023
University of California, San Francisco
2022-2023
Noninvasive ventilation (continuous positive airway pressure [CPAP] or noninvasive intermittent positive-pressure [NIPPV]) appears to be of benefit in the immediate treatment patients with acute cardiogenic pulmonary edema and may reduce mortality. We conducted a study determine whether reduces mortality there are important differences outcome associated method (CPAP NIPPV).In multicenter, open, prospective, randomized, controlled trial, were assigned standard oxygen therapy, CPAP (5 15 cm...
Abstract Background Ultrasound (US) has largely replaced contrast venography as the definitive diagnostic test for deep vein thrombosis (DVT). We aimed to derive a estimate of accuracy US clinically suspected DVT and identify study-level factors that might predict accuracy. Methods undertook systematic review, meta-analysis meta-regression cohort studies compared in patients with DVT. searched Medline, EMBASE, CINAHL, Web Science, Cochrane Database Systematic Reviews, Controlled Trials...
Delirium affects > 15% of hospitalised patients but is grossly underdetected, contributing to poor care. The 4 'A's Test (4AT, www.the4AT.com ) a short delirium assessment tool designed for routine use without special training. primary objective was assess the accuracy 4AT detection. secondary compare with another commonly used tool, Confusion Assessment Method (CAM).This prospective diagnostic test study set in emergency departments or acute medical wards involving aged ≥ 70. All those...
Objectives To measure the effectiveness and cost of providing care in a chest pain observation unit compared with routine for patients acute, undifferentiated pain. Design Cluster randomised controlled trial, 442 days to or care, analysis from health service costing perspective. Setting The emergency department at Northern General Hospital, Sheffield, United Kingdom. Participants 972 (479 attending on when was delivered unit, 493 care) followed up until six months after initial attendance....
<b>Objectives:</b> Reconfiguration of emergency services could lead to patients with life-threatening conditions travelling longer distances hospital. Concerns have been raised that this increase the risk death. We aimed determine whether distance hospital was associated mortality in emergencies. <b>Methods:</b> undertook an observational cohort study 10 315 cases transported a potentially condition (excluding cardiac arrests) by four English ambulance acute hospitals, mortality, after...
The Rapid Acute Physiology Score (RAPS) and Emergency Medicine (REMS) are risk adjustment methods for emergency medical admissions developed use in audit, research, clinical practice. Each predicts hospital mortality using four or six variables that can be easily recorded at presentation. We aimed to evaluate the predictive value of REMS, RAPS, their constituent variables.Age, heart rate, respiratory blood pressure, Glasgow Coma (GCS) oxygen saturation were 5583 patients who transported by...
Patients with chest pain represent a high health care burden, but it may be possible to identify patient group low short-term risk of adverse cardiac events who are suitable for early discharge.To compare the effectiveness rapid diagnostic pathway standard-care assessment patients in usual clinical practice setting.A single-center, randomized parallel-group trial blinded outcome assessments was conducted an academic general and tertiary hospital. Participants included adults acute consistent...
<h3>Aim</h3> To describe procedural aspects and clinical outcomes in a consecutive series of patients whom manual aspiration thrombectomy (MAT) was performed as the first treatment modality with other techniques used only case MAT did not yield recanalization. <h3>Methods</h3> A retrospective review prospectively acquired acute stroke intervention database performed. Primary carried out preference for largest catheter considered to be trackable into target occlusive lesion. The wedged...
<h3>Objectives</h3> To evaluate the role of ambulance response times in improving survival for out-of-hospital cardiac arrest (OHCA). <h3>Methods</h3> OHCAs were identified by sampling consecutive life-threatening category A emergency calls on an annual basis 5 years 1996/7–2000/1 from four services England. From these, all where arrived at scene and treated or transported a patient included study. These cohorts patients followed up to discharge hospital. <h3>Results</h3> Overall, 30 (2.6%)...
Study objectiveA 2-hour accelerated diagnostic pathway based on the Thrombolysis in Myocardial Infarction score, ECG, and troponin measures (ADAPT-ADP) increased early discharge of patients with suspected acute myocardial infarction presenting to emergency department compared standard care (from 11% 19.3%). Observational studies suggest that an using Emergency Department Assessment Chest Pain Score (EDACS-ADP) may further increase this proportion. This trial tests for existence size any...
Delirium is a common and serious neuropsychiatric syndrome, usually triggered by illness or drugs. It remains underdetected. One reason for this lack of brief, pragmatic assessment tools. The 4 'A's test (Arousal, Attention, Abbreviated Mental Test - 4, Acute change) (4AT) screening tool designed routine use. This project evaluated its usability, diagnostic accuracy cost.Phase 1 the usability 4AT in practice was measured with two surveys qualitative studies health-care professionals, review...
Objectives We aimed to derive and validate a triage tool, based on clinical assessment alone, for predicting adverse outcome in acutely ill adults with suspected COVID-19 infection. Methods undertook mixed prospective retrospective observational cohort study 70 emergency departments across the United Kingdom (UK). collected presenting data from 22445 people attending between 26 March 2020 28 May 2020. The primary was death or organ support (respiratory, cardiovascular, renal) by record...