- Neuroscience and Neuropharmacology Research
- Folate and B Vitamins Research
- Epilepsy research and treatment
- Sleep and Wakefulness Research
- Metabolism and Genetic Disorders
- Amino Acid Enzymes and Metabolism
- Diet and metabolism studies
- Pharmacological Effects and Toxicity Studies
- Neuroscience of respiration and sleep
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Sulfur Compounds in Biology
- Urinary Bladder and Prostate Research
- Neuroendocrine regulation and behavior
- Nitric Oxide and Endothelin Effects
- Stress Responses and Cortisol
- Drug-Induced Hepatotoxicity and Protection
- Mitochondrial Function and Pathology
- Ovarian function and disorders
- Biochemical effects in animals
- Birth, Development, and Health
- Sleep and related disorders
- Adipose Tissue and Metabolism
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
University of Belgrade
2015-2024
Institut za Reumatologiju
2007-2022
Rudolfinerhaus Hospital
2019-2022
Institut za filozofiju
2019
Czech Academy of Sciences, Institute of Physiology
2012-2015
University of Belgrade – Faculty of Medicine
2014
Serbian Academy of Sciences and Arts
2006-2013
Grade Medical (Czechia)
2006
The aim of the study was to compare effects high-intensity interval training (HIIT) and nutrition advice on cardiometabolic biomarkers, hormonal parameters, cardiorespiratory fitness in adolescent girls with obesity. Adolescent obesity (n = 44, aged 13–19 years) were randomized into a 12-week intervention as follows: (i) dietary HIIT 22), (ii) only 22). concentration biomarkers inflammation, biochemical testing, oral glucose tolerance test, fitness, physical activity levels, assessed. After...
Mechanisms of the brain‐related comorbidities in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still largely unknown, although CP/CPPS is one major urological problems middle‐aged men, while these neuropsychological incapacities considerably diminish life quality. The objectives this study were to assess behavioral patterns rats with and determine whether depend on alterations brain oxidative stress, corticosterone, hippocampal parvalbumin‐positive (PV+) interneurons. Adult...
To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions.Prospective cohort STEMI within 24 h symptom onset (11 462 patients, 196 centres, 26 European Society Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre primary PCI was 40 min (interquartile range 20-74) with 65.8% receiving guideline recommendation 60 min. A third patients...
The aim of this study was to examine the effects a methionine-enriched diet on anxiety-related behavior in rats and determine role brain oxidative status these alterations. Adult male Wistar were fed from 30th 60th postnatal day with standard or (double content comparing diet: 7.7 g/kg). Rats tested open field light-dark tests afterwards different regions determined. Hyperhomocysteinemia induced by decreased number rearings, as well time that animals spent center field, but increased index...
Neurosteroids are involved in the pathogenesis of hepatic encephalopathy (HE). This study evaluated effects finasteride, inhibitor neurosteroid synthesis, on motor, EEG, and cellular changes rat brain thioacetamide-induced HE. Male Wistar rats were divided into following groups: 1) control; 2) thioacetamide-treated group, TAA (300 mg·kg −1 ·day ); 3) finasteride-treated FIN (50 4) group treated with (FIN + TAA). Daily doses administered three subsequent days intraperitoneally, was 2 h before...
Anxiety is one of the most frequent psychiatric disorders. Despite fact that studies describe an anxiolytic effect testosterone, hyperandrogenemia in mothers assumed to be related increased risk mood disorders their offspring. An increasing body scientific evidence suggests altered expression interneuronal markers hippocampus may cause anxiety. The aim this study was examine influence maternal on behavioral parameters anxiety-like behavior, neuropeptide Y (NPY) and parvalbumin (PV)...
Introduction The neuroendocrine background of acute sleep fragmentation in obstructive apnea and involvement psychiatric comorbidities, common these patients, are still largely unknown. aim this study was to determine the effects short-term experimental on anxiety -like behavior hormonal status rats. Methods Male rats were adapted treadmill (ON OFF mode with belt speed set 0.02m/s 0.00m/s) randomized to: 1) control (TC, only mode); 2) motion, activity (AC, 10min ON 30min mode) 3) (SF, 30s...
The aim of our study was to investigate the behavioral and electroencephalographic manifestations thioacetamide-induced encephalopathy in rats. Male Wistar rats were divided among (i) control, saline-treated, (ii) thioacetamide-treated groups (TAA(300) (300 mg/kg body mass); TAA(600) (600 mg/kg); TAA(900) (900 mg/kg)). daily dose thioacetamide mg/kg) administered intraperitoneally once (TAA(300)), twice (TAA(600)), or 3 times (TAA(900)), on subsequent days. Behavioral determined at 0, 2, 4,...
The aim of the study was to examine effects chronic exercise training on seizures induced by homocysteine thiolactone (HCT) in adult rats. Rats were assigned to: sedentary control; sedentary+HCT; exercise+HCT group. Animals groups ran 30 min daily a treadmill for consecutive days (belt speed 20 m/min), while rats spent same time (speed 0 m/min). On 31st day, HCT received (8.0 mmol/kg), control vehicle. Afterwards, convulsive behavior and EEG activity registered. Lipid peroxidation,...
In Brief The assessment of pain sensitivity in humans has been standardized using quantitative sensory testing, whereas animals mostly paw withdrawal thresholds to diverse stimuli are measured. This study directly compares tests used testing (pinpricks, pressure algometer) with animal studies (electronic von Frey test: evF), which we applied the dorsal hind limbs after high frequency stimulation and rats tibial nerve transection. Both experimental models induce profound mechanical...
Pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) remains unclear since it represents an interplay between immunological, endocrine, and neuropsychiatric factors. Patients suffering from CP/CPPS often develop mental health-related disorders such as anxiety, depression, or cognitive impairment. The aim this study was to investigate depression-like behavior, learning, memory processes in a rat model determine the alterations hippocampal structure function. Adult male...