- Periodontal Regeneration and Treatments
- Muscle metabolism and nutrition
- Dental Trauma and Treatments
- Bone Tissue Engineering Materials
- Mesenchymal stem cell research
- Cleft Lip and Palate Research
- Proteoglycans and glycosaminoglycans research
- Health and Wellbeing Research
- Bone and Dental Protein Studies
- Muscle Physiology and Disorders
- Dental Implant Techniques and Outcomes
- Cardiovascular and exercise physiology
- Nutrition and Health in Aging
- Collagen: Extraction and Characterization
- Endodontics and Root Canal Treatments
Aichi Gakuin University
2022-2024
Baylor University
2011
The University of Queensland
2011
Texas A&M University
2011
In this study, we developed porous medium cross-linked recombinant collagen peptide (mRCP) with two different ranges of interconnected pore sizes, Small-mRCP (S-mRCP) a range 100-300 μm and Large-mRCP (L-mRCP) 200-500 μm, to compare the effect size on bone regeneration in calvarial defect.Calvarial defects were created Sprague-Dawley rats through surgical procedure. The divided into 2 groups: S-mRCP implanted group L-mRCP group. newly formed volume mineral density (BMD) was evaluated by...
Adipose-derived stem cells (ASCs) secrete various growth factors to promote wound healing and regenerate tissues, such as bone, cartilage, fat tissue. Subcutaneous adipose tissue is a considerable cell source in clinical practice can be collected relatively easily safely under local anesthesia. Moreover, platelet-rich plasma (PRP), component containing many platelets purified by centrifuging the blood, also promotes healing. PRP gelled therefore attracting attention scaffolding material for...
Regenerative endodontic procedures (REPs) are promising for dental pulp tissue regeneration; however, their application in permanent teeth remains challenging. We assessed the potential combination of an REP and local cell (DPC) transplantation mature molars C57BL/6 mice with (REP + DPC group) or without DPCs from green fluorescent protein (GFP) transgenic mice. After 4 weeks, regenerated was evaluated by micro-computed tomography histological analyses to detect odontoblasts, vasculogenesis,...
We recently demonstrated the bone-forming potential of medium-cross-linked recombinant collagen peptide (mRCP) in animal models bone defects. However, these studies were limited to a 4-week observation period; therefore, present study, we aimed further evaluate mRCP as suitable graft material for alveolar cleft by analyzing its potential, osteogenic-inducing ability, and biodegradation over an extended period 12 weeks, using rat critical-size calvarial defect model.Using Sprague-Dawley rats,...
In this study, we report that a proteoglycans (PGs)-layer between the bone and titanium dioxide (TiO2) surface after osseointegration improved calcification capacity immunotolerance of human marrow mesenchymal stem cells (hBMSCs) on TiO2. Alkaline treatment TiO2 is method for promoting osteogenesis in hBMSCs. We hypothesized promotion due to alkaline was caused by changing PGs-layer This study aimed analyze whether affects formation The topology wettability alkaline-treated (Ti-Al)...
PURPOSE: To compare whey and casein protein combined with a 12-week resistance training program on systemic cellular mechanisms regulating skeletal muscle hypertrophy in older males. METHODS: Thirty-six non-resistance trained males (62.5±6.8 yrs, 177±6.32 cm, 95.25±16.9 kg) were randomized double blind manner to ingest either (WP) [20g/d WP + 5g carbohydrate (CHO)], (CAS) (20g/d CAS CHO) or maltodextrose placebo (CHO) [25g/d CHO] while participating supervised high intensity (3 sets x 10...
PURPOSE: To examine the effects of ingesting free leucine on training-induced changes in body composition and muscle strength older males. METHODS: Twenty three non-resistance trained males (61.22 ± 7.13 yrs, 176.93 5.99 cm, 92.59 14.59 kg) were randomized a double blind manner. Participants ingested either (LEU) [3g/d LEU + 5g carbohydrate (CHO)] or maltodextrose (CHO) (5g/d CHO) while participating supervised high intensity resistance training program (3 sets × 10 repetitions at 75% 1RM),...