A5018490093- Pediatric Pain Management Techniques
- Childhood Cancer Survivors' Quality of Life
- Infant Development and Preterm Care
- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Autoimmune and Inflammatory Disorders Research
- Musculoskeletal pain and rehabilitation
- Adolescent and Pediatric Healthcare
- Pain Mechanisms and Treatments
- Opioid Use Disorder Treatment
- Pharmaceutical studies and practices
- Anesthesia and Sedative Agents
- Pain Management and Placebo Effect
- Ethics and Legal Issues in Pediatric Healthcare
- Botulinum Toxin and Related Neurological Disorders
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Rheumatoid Arthritis Research and Therapies
- Anesthesia and Neurotoxicity Research
- Cerebral Palsy and Movement Disorders
- Neurogenetic and Muscular Disorders Research
- Asthma and respiratory diseases
- Cardiovascular Syncope and Autonomic Disorders
- Religion, Spirituality, and Psychology
- Veterinary Pharmacology and Anesthesia
University of Washington
2016-2025
Seattle Children's Hospital
2010-2022
Seattle University
2013-2022
Pain Management Institute
2013
Hackensack University Medical Center
1997-2009
Center for Children
2003-2008
Rutgers, The State University of New Jersey
1992-2007
Rutgers New Jersey Medical School
1998-2007
Children's Hospital of Michigan
2005
Sterling Research Group
2003
Recent advances in neurobiology and clinical medicine have established that the fetus newborn may experience acute, established, chronic pain. They respond to such noxious stimuli by a series of complex biochemical, physiologic, behavioral alterations. Studies concluded controlling pain is beneficial with respect short-term perhaps long-term outcomes. Yet, pain-control measures are adopted infrequently because unresolved scientific issues lack appreciation for need control its sequelae...
It has long been recognized that patients receive less relief from pain than they should1,2. A recent review concluded can be relieved effectively in 90 percent of but is not 80 patients3. The tendency toward undermedication for even more pronounced children adults4. There are large discrepancies between the amounts postoperative analgesia ordered and administered to adults those who have same diagnoses undergone procedures5,6.Interest control .
Appropriate outcome measures and high-quality intervention trials are critical to advancing care for children with chronic pain. Our aim was update a core set pediatric pain interventions. The first phase involved collecting providers', patients', parents' perspectives about treatment of understand clinically meaningful outcomes be routinely measured. second reach consensus mandatory optional domains following the OMERACT framework. A modified Delphi study 2 rounds conducted including 3...
Objective: Examine cognitive and academic late effects among children adolescents who had received central nervous system (CNS) prophylactic chemotherapy alone for acute lymphocytic leukemia (ALL); none whole brain radiation therapy (RT).
Decreasing chronic joint pain is a major goal in the management of juvenile rheumatoid arthritis. Cognitive-behavioral self-regulatory techniques were taught to children with arthritis reduce musculoskeletal intensity and facilitate better adaptive functioning. Subjects 13 between ages 4.5 16.9 years who had pauciarticular or systemic onset Baseline data included an initial comprehensive assessment pain, disease activity, level functional disability, as well ratings gathered over 4-week...
Analgesic trials pose unique scientific, ethical, and practical challenges in pediatrics. Participants a scientific workshop sponsored by the US Food Drug Administration developed consensus on aspects of pediatric analgesic clinical trial design. The standard parallel-placebo design commonly used for adults has ethical difficulties pediatrics, due to likelihood subjects experiencing pain extended periods time. Immediate-rescue designs using opioid-sparing, rather than scores, as primary...
Abstract Many gaps remain in finding effective, safe, and equitable treatments for children adolescents with chronic pain accessing different settings. A major goal of the field is to improve assessment related experience. Valid reliable patient-reported outcome measures are critical advancing knowledge clinical interventions pediatric pain. Building on work Ped-IMMPACT group, we previously updated a core set (COS) trials using stakeholder feedback from providers, youth, parents. The new COS...
In sickle cell disease, vaso-occlusion in the small blood vessels leads to bone or joint pain which is variable intensity and duration. An essential first step toward development of specific treatment guidelines for such painful episodes children adolescents accurate evaluation pain. The systematic assessment vaso-occlusive addressed through two separate studies. first, 35 pediatric disease patients between 5 16 years age were evaluated an outpatient clinic with Varni/Thompson Pediatric Pain...
To examine temperament, stress response, child psychological adjustment, family environment, pain sensitivity, and response differences between children adolescents with juvenile primary fibromyalgia syndrome (JPFMS), arthritis, healthy controls. Parental adjustment was also measured.Subjects included 16 JPFMS, Participants completed the Dimensions of Temperament Survey-Revised (DOTS-R), State-Trait Anxiety Inventory, Children's Depression Family Environment Scale (FES), Sensitivity...
To better understand parental perceptions of the informed consent process in pediatric oncology clinical trials, 20 parents newly diagnosed children at two cancer centers described their a semi-structured interview. They recalled well diagnosis, general treatment plan, and statistics survival and/or cure, but research nature particularly randomization, was not understood. However, despite need to assimilate great deal information, time pressure make decisions, reportedly high levels distress...
The relation between pain and joint inflammation in patients with juvenile rheumatoid arthritis has not previously been systematically evaluated. Eighteen completed paediatric questionnaires the joints affected were examined by thermography. Although significant correlations shown parent doctor intensity ratings temperature, of patient temperature only younger children. degree is one factor several contributing to amount subjective experienced children arthritis, indicating need for a...
To examine the relationship among different indicators of pain and distress, including self-report, behavioral observations, physiological parameters, in children with cancer undergoing invasive procedures.Forty-eight between ages 3.1 17.7 years were evaluated while lumbar punctures. Self-report measures assessed anxiety, pain, self-efficacy, expectations coping strategies, self-efficacy. Parents reported on their own child's levels physicians estimated level stress technical difficulty...