A5064588609- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Ferroptosis and cancer prognosis
- Herpesvirus Infections and Treatments
- Bacteriophages and microbial interactions
- FOXO transcription factor regulation
- Cancer-related molecular mechanisms research
University of Bologna
2022-2024
The Mpox (formerly named Monkeypox) virus is the etiological cause of a recent multi-country outbreak, with thousands distinct cases detected outside endemic areas Africa as December 2023. In this article, we analyze sequences full genomes from Europe and compare them all available historical relevance, annotated by year geographic origin, well related Cowpox Variola (smallpox) sequences. Our results show that outbreak most likely originating West African clade Mpox, >99 % sequence identity...
Abstract The Monkeypox virus is the etiological cause of a recent multi-country outbreak, with nearly one hundred distinct cases detected outside endemic areas Africa in May 2022. In this article, we analyze sequences two full genomes from Portugal and Belgium, compare them all available sequences, annotated by year geographic origin, as well related Cowpox Variola (smallpox) sequences. Our results show that outbreak most likely originating West African clade Monkeypox, >99% sequence...
The human FOXM1 transcription factor controls cell cycle progression and genome stability, it has been correlated to the onset of many tumor types. In our study, we collected all recent sequence quantitative transcriptomics data about FOXM1, testing its presence across vertebrate evolution upregulation in cancer, both bulk tissue contexts (by comparing TCGA dataset GTEx normal dataset) single-cell contexts. is significantly consistently upregulated tested types, as well cells within a cancer...