Levent Tök

ORCID: 0000-0003-0819-915X
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Retinopathy of Prematurity Studies
  • Ocular Surface and Contact Lens
  • Retinal Diseases and Treatments
  • Corneal surgery and disorders
  • Neonatal Respiratory Health Research
  • Traumatic Ocular and Foreign Body Injuries
  • Corneal Surgery and Treatments
  • Restraint-Related Deaths
  • Migraine and Headache Studies
  • Ocular Diseases and Behçet’s Syndrome
  • Retinal and Optic Conditions
  • Neonatal and fetal brain pathology
  • Retinal Imaging and Analysis
  • Neonatal Health and Biochemistry
  • Facial Trauma and Fracture Management
  • Ophthalmology and Eye Disorders
  • Ocular Oncology and Treatments
  • Optical Coherence Tomography Applications
  • Ophthalmology and Visual Impairment Studies
  • Retinal Development and Disorders
  • Ocular Disorders and Treatments
  • Connexins and lens biology
  • Trauma Management and Diagnosis
  • MicroRNA in disease regulation

Süleyman Demirel University
2013-2025

Suleyman Demirel University Research and Education Hospital
2015-2024

Suleyman Demirel University
2014-2023

Konya Eğitim ve Araştırma Hastanesi
2021

Türkiye Yüksek İhtisas Hastanesi
2014

Ministry of Health
2011-2014

Ankara Yıldırım Beyazıt University
2014

Ophthalmology Associates (United States)
2011

Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2010-2011

Isparta University of Applied Sciences
2011

10.1016/j.jaapos.2011.06.012 article EN Journal of American Association for Pediatric Ophthalmology and Strabismus 2011-12-01

Background: To investigate the factors that influence final visual acuity (VA) in open globe injuries. Methods: The records of patients with injuries who were followed for longer than 6 months between 1998 and 2009 two different centers retrospectively reviewed. data collected included patients' demographics as well their initial VA, wound location, mechanism type injury, clinical findings, best-corrected VA. Statistical analysis was conducted using univariate multiple logistic regression...

10.1097/ta.0b013e31822b46af article EN Journal of Trauma and Acute Care Surgery 2011-12-01

Purpose: We aimed to determine applicable guidelines for screening of retinopathy prematurity (ROP), and evaluate the contribution risk factors severe ROP.Methods: A prospective cohort study neonates with a gestational age (GA) < 34 weeks or birth weight 2000g who were admitted Neonatal Intensive Care Unit (NICU) tertiary level hospital was conducted. The group classified into three groups according eye examination findings as no ROP, mild ROP ROP.Results: Of 700 screened, frequencies any...

10.3109/09286586.2011.615449 article EN Ophthalmic Epidemiology 2011-11-04

To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with Alzheimer disease (AD) and to compare results those of healthy controls.Forty (mean age: 75.02 ± 6.34 years; 23 women) untreated AD 40 age-, sex-, education-matched were examined this case-control prospective study. All underwent detailed ophthalmic neurological examination. The Mini Mental State Examination (MMSE) was performed RNFL measured using spectral-domain optical coherence tomography. association between...

10.3906/sag-1405-114 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2015-01-01

Background: Despite the importance of oxidative stress and apoptosis through mitochondrial depolarization in neurodegenerative diseases, their roles etiology glaucoma are poorly understood. We aimed to investigate whether formation altered rat pheochromocytoma-derived cell line-12 (PC12) neuronal cultures exposed elevated different hydrostatic pressures as a culture model glaucoma. Materials: Cultured PC12 cells were subjected 0, 15 70 mmHg pressure for 1 24 h. Then, following values...

10.3109/10799893.2014.910812 article EN Journal of Receptors and Signal Transduction 2014-05-08

To investigate changes in corneal parameters and the tear film after botulinum toxin-A (BTX-A) injection patients with blepharospasm or hemifacial spasm.Twelve benign essential 30 spasm treated BTX-A were included this study. Disease severity was evaluated using Jankovic scale. Corneal measured by Pentacam. The Schirmer test score, breakup time, fluorescein staining value, Ocular Surface Index score also evaluated.The treatment relieved spasms all of patients. There a statistically...

10.1097/ico.0000000000000482 article EN Cornea 2015-06-13

Purpose: To evaluate retinal nerve fiber layer (RNFL) thickness in migraine patients with unilateral headache.Methods: A total of 58 diagnosed headache consistently occurring on the same side and age-and sex-matched healthy subjects were evaluated this cross-sectional study.RNFL was measured using spectral-domain optical coherence tomography, compared contralateral as well results subjects.Results: The mean patient age 33.05 ± 8.83 years, that 31.44 8.64 years (p = 0.32).The duration disease...

10.3341/kjo.2016.30.2.134 article EN cc-by-nc Korean Journal of Ophthalmology 2016-01-01

Purpose: To evaluate the effect of subconjunctival injection dexpanthenol on corneal neovascularization and inflammation in rats with induced chemical burns. Methods: This experimental study included 40 female albino Wistar rats. Chemical burns were right eye all first day, left was used as a control. Rats randomly divided into 5 groups. The no-treatment group (group 1) received no injections. Balanced salt solution sham 2), 3), bevacizumab 4), combined 5) administered subconjunctivally day...

10.1097/ico.0000000000003804 article EN Cornea 2025-01-14

Context: Migraine is a frequent and disabling chronic neurological condition with complex pathophysiology. Both cigarette smoking migraine may cause damage to the optic nerve. Objective: The primary objective of this study was investigate effect on retinal nerve fiber layer (RNFL) thickness in patients migraine.Materials methods: Eighty-four consecutive diagnosed (34 smokers 50 nonsmokers) 66 age- gender-matched healthy non-smoker controls were enrolled for observational cross-sectional...

10.3109/15569527.2014.1003935 article EN Cutaneous and Ocular Toxicology 2015-01-19

Purpose: Laser-assisted epilation of eyebrow hair has become a common practice, but number ocular complications can occur. We report the cases 2 patients who had unilateral anterior uveitis after having undergone laser removal hair. Methods: This describes experienced eye pain, photophobia, redness, and edema undergoing alexandrite (755 nm) area while not wearing protective eyewear or corneal shield. Results: Eye examinations revealed that both conjunctival injection, endothelial keratic...

10.1097/ico.0000000000000294 article EN Cornea 2014-10-30

We present the case of a four-year-old girl with bilateral keratoconus secondary to chronic persistent eye rubbing. She was referred our clinic intractable ocular itching and low vision. According her family, she generally rubbing eyes. On slit-lamp biomicroscopic examination, papillary reactions were seen on upper tarsal conjunctiva. Clinical examination corneal topography compatible keratoconus. The patient's visual acuity not evaluated because cooperation difficulties. Systemic normal. In...

10.3109/08820538.2013.874480 article EN Seminars in Ophthalmology 2014-02-07

&lt;b&gt;&lt;i&gt;Purpose:&lt;/i&gt;&lt;/b&gt; The purpose of this study was to document clinical findings and management a patient with bilateral globe luxation optic nerve transection. &lt;b&gt;&lt;i&gt;Materials Methods:&lt;/i&gt;&lt;/b&gt; A 25-year-old female admitted the emergency department traumatic following motor vehicle accident. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; Visual acuity testing showed no light perception. right pupil dilated bilaterally did not react light....

10.1159/000370043 article EN cc-by-nc Case Reports in Ophthalmology 2014-12-10

To evaluate central corneal thickness (CCT) and peripheral (PCT) in patients with rheumatoid arthritis (RA) to assess the relationships among parameters, dry eye disease, clinical variables of RA.A total 58 RA control subjects participated this study. A detailed ophthalmological examination was performed on each subject. Dry evaluation using Schirmer's test, tear break-up time (TBUT), fluorescein staining, Ocular Surface Disease Index (OSDI). Corneal at apex point, center pupil, thinnest PCT...

10.5935/0004-2749.20150061 article EN Arquivos Brasileiros de Oftalmologia 2015-01-01

To evaluate the clinical findings of toxic keratopathy associated with abuse topical anesthetics and treatment efficacy amniotic membrane transplantation (AMT).Fifteen eyes 10 patients were included in this study. The data collected patients' demographic information, initial best corrected visual acuity (BCVA), findings, time to AMT, duration epithelization, additional treatments, posttreatment BCVA, results psychiatric examination.All male, mean age 37.9±5.4y. had received 0.5% proparacaine...

10.3980/j.issn.2222-3959.2015.05.15 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2015-01-01

Purpose: To evaluate refractive errors in patients with migraine headache and to compare healthy subjects. Materials Methods: This prospective case-control study includes age- sex-matched Clinical demographic characteristics of the were noted. Detailed ophthalmological examinations performed containing spherical error, astigmatic equivalent (SE), anisometropia, best-corrected visual acuity, intraocular pressure, slit lamp biomicroscopy, fundus examination, axial length, anterior chamber...

10.3109/08820538.2014.962177 article EN Seminars in Ophthalmology 2014-11-20

To investigate the prevalence of pseudoexfoliation syndrome (PEX) among Turkish patients with senile cataract.Records 352 eyes who underwent cataract surgery were analyzed in this retrospective study. The presence PEX, type cataract, intraocular pressure (IOP), glaucoma, age-related macular degeneration, and systemic diseases (coronary artery disease, hypertension, diabetes mellitus) recorded.The overall PEX was detected to be 11%. mean age significantly higher than without (74.4 ± 7.2 years...

10.3109/08820538.2015.1068344 article EN Seminars in Ophthalmology 2016-01-21

Background/aim: To compare the cognitive functions and define frequency of Alzheimer disease (AD) between participants with without age-related macular degeneration (AMD). Materials methods: Fifty-nine patients late-stage AMD (74.3 ± 7.3 years) 49 age-, sex-, education-matched control subjects were compared for presence AD according to guidelines National Institute Neurological Communicative Disorders Stroke Alzheimer's Disease Related Association (NINCDS-ADRDA). Detailed neuropsychological...

10.3906/sag-1406-135 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2015-01-01

To evaluate corneal parameters of patients with ankylosing spondylitis (AS) by Scheimpflug imaging and also to clarify the associations between disease severity clinical status AS parameters.Fifty-seven 57 healthy subjects were included in this cross-sectional study. All participants underwent a detailed ophthalmological evaluation. Corneal measured Pentacam. In addition, Schirmer test, tear break-up time (TBUT), fluorescein staining, Ocular Surface Disease Index (OSDI) scores evaluated....

10.3109/08820538.2015.1068340 article EN Seminars in Ophthalmology 2015-09-04

To evaluate anterior segment parameters in patients with pseudoexfoliation syndrome (PXS) using Scheimpflug imaging.Forty-three PXS and 43 healthy control subjects were included this cross-sectional study. All participants underwent a detailed ophthalmologic examination. Anterior measured system.Considering the groups, mean corneal thicknesses at apex point (536 ± 31 560 µm, respectively, p=0.001), center of pupil (534 558 33 thinnest (528 30 546 27 p=0.005) significantly thinner patients....

10.5935/0004-2749.20160051 article EN Arquivos Brasileiros de Oftalmologia 2016-01-01

AMAÇAçık göz küresi yaralanması olan geriatrik hastaların demografik ve etyolojik özelliklerini değerlendirmeyi, prognozu etkileyen faktörleri tespit etmeyi güncel literatür eşliğinde genç nüfusla farklılıkları karşılaştırmayı

10.5505/tjtes.2011.67503 article TR Turkish Journal of Trauma and Emergency Surgery 2011-01-01

Circulation miRNAs have emerged as new biomarkers for identifying and monitoring the microvascular complications of diabetes. The aim this study is to evaluate levels five candidate (miR-29c-3p, miR-18a, miR-31, miR-181 miR-20a) in patients with diabetic retinopathy (DR) their relationship disease severity.The included 31 diabetes without DR (NDR group), 68 (DR group) 30 healthy controls (HC group). Twenty-five were proliferative (PDR 43 non-proliferative (NPDR patients. Metabolic parameters...

10.23736/s0391-1977.20.03278-2 article EN Minerva Endocrinology 2020-11-01
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