A5101657449- Traditional and Medicinal Uses of Annonaceae
- Alkaloids: synthesis and pharmacology
- Geochemistry and Geologic Mapping
- Natural product bioactivities and synthesis
- Wireless Signal Modulation Classification
- Chemical synthesis and alkaloids
- Berberine and alkaloids research
- Geological and Geochemical Analysis
- Phytochemistry and Biological Activities
- Metal Extraction and Bioleaching
- Microbial Natural Products and Biosynthesis
- Geochemistry and Geochronology of Asian Mineral Deposits
- Biological Activity of Diterpenoids and Biflavonoids
- Radar Systems and Signal Processing
- Hydrocarbon exploration and reservoir analysis
- Computational Drug Discovery Methods
- Synthesis and Biological Activity
- Cancer Immunotherapy and Biomarkers
- Cholinesterase and Neurodegenerative Diseases
- Phytochemistry and Bioactive Compounds
- Sulfur Compounds in Biology
- Heat Transfer and Optimization
- Pharmacogenetics and Drug Metabolism
- Molecular Sensors and Ion Detection
- Bioactive natural compounds
Lanzhou Institute of Chemical Physics
2024-2025
Chinese Academy of Sciences
2008-2025
Shandong Normal University
2025
University of Chinese Academy of Sciences
2024
University of Electronic Science and Technology of China
2021-2023
Xi'an Jiaotong University
2020-2023
Zhejiang Chinese Medical University
2014
Zhenjiang College
2013
State Key Laboratory of Continental Dynamics
2007
Northwest University
1991-2007
Automatic modulation recognition (AMR) is a promising technology for intelligent communication receivers to detect signal schemes. Recently, the emerging deep learning (DL) research has facilitated high-performance DL-AMR approaches. However, most models only focus on accuracy, leading huge model sizes and high computational complexity, while some lightweight low-complexity struggle meet accuracy requirements. This letter proposes an efficient based phase parameter estimation transformation,...
This article proposes an autoencoder-based method to enhance the information interaction between in-phase/quadrature (I/Q) channels of input data for automatic modulation recognition (AMR). The proposed utilizes autoencoder built by fully-connected layers correlate features I/Q and obtain feature from intermediate layer, which is concatenated together with original as model inputs. To accommodate new dimensions, a modification scheme existing representative deep learning based AMR (DL-AMR)...
Abstract In most metazoans, centrosome elimination during oogenesis ensures accurate centriole inheritance in the zygote, yet molecular mechanisms remain poorly understood. Here, we reveal a critical role for controlled SAS-6 phosphorylation dynamics oogenesis. Centrioles disassemble late meiotic prophase, while cartwheel protein exhibits dynamic behavior early prophase. Purified undergoes phase separation vitro, and overexpressed forms droplets cells. Mass spectrometry kinase assays that is...
The liver is an essential metabolic organ that involved in energy metabolism, protein synthesis, and detoxification. Many endogenous exogenous factors can cause injury, a complex pathological condition. It poses serious risk to human health due its extremely varied clinical manifestations, which range from mild fatty fibrosis, cirrhosis, even hepatocellular carcinoma. Because of their low specificity, lack real-time monitoring, invasiveness, traditional diagnostic techniques for such as...
Abstract Two new yohimbine‐type monoterpene indole alkaloids, rauvines A and B, six known derivatives were obtained from the leaves of R. vomitoria . The structures B determined by extensive spectroscopic analyses, 13 C‐NMR, ECD calculations. This is first time to determine absolute configurations N ‐oxides quantum chemistry calculations ( C‐NMR calculations). All isolates tested for their cytotoxicity against five human cancer cell lines. Rauvine showed moderate on MCF‐7 breast, SWS80...
Twelve new Cephalotaxus alkaloids (1-12) and nine known analogues (13-21) were isolated identified from the twigs leaves of sinensis. The structures compounds elucidated by extensive spectroscopic analysis single-crystal X-ray diffraction analysis. Cephalosine H (8) is third example an alkaloid containing cephalolancine skeleton. Cephalosines J K (10 11) are rare natural Δ(2)1-alkene-6-hydroxyl homoerythrina-type genus. racemization cephalotaxine-type discussed. Alkaloids 6, 7, 11, 16, 18 19...
Alscholarines A and B (1 2), two unprecedented rearranged monoterpene indole alkaloids, were isolated from Alstonia scholaris. Alscholarine (1) features an imidazole ring fused with a vallesamine-type alkaloid possessing unparalleled 6/5/6/6 tetracyclic skeleton through C7-C-19 connectivity. (2), incorporating unusual 7-oxa-1-azabicyclo[3.2.1]octane moiety, represents unique 6/5/6/6/5 system via C-6-C-20 Their structures established by spectroscopic analysis, X-ray crystallography,...
One new compound and 13 known compounds were isolated from Aspergillus niger, a plant endophytic fungus of Pachysandra terminalis collected Qinling Mountains, Xi'an, China. The structure 1 was classically determined by extensive spectroscopic analysis. Compounds 5, 6, 8, 14 first reported Aspergillus, while 2 A. niger for the time. All further evaluated their antioxidant α-glucosidase inhibitory activities. 3 exhibited significant activities with IC50 values 31.64 μm 24.32 μm, respectively,...
Four undescribed biflavonoid alkaloids, sinenbiflavones A-D, were isolated from Cephalotaxus sinensis using a MS/MS-based molecular networking guided strategy. Their structures elucidated by series of spectroscopic methods (HR-ESI-MS, UV, IR, 1D, and 2D NMR). Sinenbiflavones A-D are the first examples amentoflavone-type (C-3'-C-8'') alkaloids. Meanwhile, B D unique C-6-methylated Sinenbiflavone showed weak SARS-CoV-2 3CLpro inhibitory activity with 43 % inhibition rate at 40 μM.
Alscholarine C, a polycyclic pyrroloindoline-containing natural product with unique 3-heptyl-2a,4a-diazapentaleno[1,6- ab ]indene core, was isolated from Alstonia scholaris .
The significance of hydrogen sulfide (H2S) in biological research is covered detail this work. H2S a crucial gas-signaling molecule that involved wide range illnesses and processes. Whether has beneficial therapeutic effect or negative pathological toxicity an organism depends on changes its concentration. A novel approach to treatment the regulation production by medications other measures. Furthermore, useful marker for disease assessment because dual nature sensitivity. We can better...