Keith Seymour

ORCID: 0000-0003-0850-2745
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Bariatric Surgery and Outcomes
  • Gallbladder and Bile Duct Disorders
  • Appendicitis Diagnosis and Management
  • Immunotherapy and Immune Responses
  • Biliary and Gastrointestinal Fistulas
  • Pancreatic and Hepatic Oncology Research
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pancreatitis Pathology and Treatment
  • Body Contouring and Surgery
  • Obesity and Health Practices
  • Colorectal Cancer Surgical Treatments
  • Liver Disease Diagnosis and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Diet and metabolism studies
  • Gastrointestinal motility and disorders
  • Esophageal and GI Pathology
  • Minimally Invasive Surgical Techniques
  • Parallel Computing and Optimization Techniques
  • Cancer Genomics and Diagnostics
  • Surgical Simulation and Training
  • Cardiac, Anesthesia and Surgical Outcomes
  • COVID-19 Clinical Research Studies
  • Intensive Care Unit Cognitive Disorders
  • Gastric Cancer Management and Outcomes

Musgrove Park Hospital
2023

The University of Melbourne
2020

Austin Health
2020

Peninsula Health
2020

Eastern Health
2020

Monash Health
2020

Monash University
2020

University of Glasgow
2020

Australian Catholic University
2020

St Vincent's Health
2020

Abstract Objective The aim of this study was to explore women's experience menopause care after breast cancer in the UK. Methods This is a thematic analysis free-text comments an online survey that asked women about their cancer. A coding framework used mapped eight domains patient (deductive analysis). An inductive approach identify subthemes within each domains. Results total 1,195 completed survey. Two hundred twenty-six (18.9%) left response questions shared decision making and...

10.1097/gme.0000000000002505 article EN cc-by-nc-nd Menopause The Journal of The North American Menopause Society 2025-02-25

This paper describes the application of various search techniques to problem automatic empirical code optimization. The process is a critical aspect auto-tuning systems because large size space and cost evaluating candidate implementations makes it infeasible find true optimum point by brute force. We evaluate effectiveness Nelder-Mead Simplex, Genetic Algorithms, Simulated Annealing, Particle Swarm Optimization, Orthogonal search, Random in terms performance best found under varying time limits.

10.1109/clustr.2008.4663803 article EN 2008-09-01

The impact of weight loss on obesity-related colorectal cancer (CRC) risk is not well defined. Previous studies have suggested that Roux-en-Y gastric bypass (RYGB) surgery may an unexpected adverse CRC risk. This study aimed to investigate the RYGB biomarkers risk.Rectal mucosal biopsies and blood were obtained from patients undergoing (n = 22) non-obese control participants 20) at baseline a median 6.5 months after surgery. Markers systemic inflammation glucose homeostasis measured....

10.1007/s11695-017-2953-6 article EN cc-by Obesity Surgery 2017-10-08

Bariatric procedures are increasingly being used to combat the rising obesity epidemic. The aim of this study was assess effect these interventions on bowel habit.We recruited obese adults listed for a bariatric procedure. Demographic data, medical history, medications and anthropometric measurements were recorded. Bowel habit characterized using 7-day Bristol Stool Form Scale (BSFS) diary. A validated food frequency questionnaire (FFQ) diet.Twenty-six patients assessed pre-operatively at...

10.1007/s11695-016-2100-9 article EN cc-by Obesity Surgery 2016-02-19

Summary Despite the capacity for antigen‐specific activation and rapid clonal expansion, homeostatic mechanisms ensure that mature immune system contains a relatively stable number of T cells. In recent years, it has become apparent this stability is consequence apoptotic death most specific cells generated during an response. Clearly process must be tightly regulated in order to retain sufficient T‐cell progeny mediate effective response, whilst allowing deletion these at end response...

10.1046/j.1365-2567.2000.00048.x article EN Immunology 2000-07-01

Pancreatic cancer is an aggressive and potent disease, which largely resistant to conventional forms of treatment. However, the discovery antigens associated with pancreatic cells has recently suggested possibility that immunotherapy might become a specific effective therapeutic option. T within many epithelia, including those pancreas, are known express αEβ7-integrin adhesion molecule, CD103. The only characterised ligand for CD103 E-cadherin, epithelial molecule exhibits reduced expression...

10.1038/sj.bjc.6600597 article EN cc-by-nc-sa British Journal of Cancer 2002-10-01

C olorectal carcinoma is a common disease with 25,000 new cases in the UK per year; 17,000 fatalities, it second most cause of cancer-related death.Of cases, 8-30% will present complete or partial large bowel obstruction -somewhere region 2000-7500 annum UK. 1,2Three-quarters lesions causing be found to descending and rectosigmoid as here stool becomes less fluid. 3Traditionally, management patients colonic has been one two A comparison methods palliation due irremovable colon cancer

10.1308/003588404322827473 article EN Annals of The Royal College of Surgeons of England 2004-02-24

The enormous and growing complexity of today's high-end systems has increased the already significant challenges obtaining high performance on equally complex scientific applications. Application scientists are faced with a daunting challenge in tuning their codes to exploit performance-enhancing architectural features. Performance Engineering Research Institute (PERI) is working toward goal automating portions process. This paper describes PERI's overall strategy for auto-tuning tools...

10.1088/1742-6596/125/1/012089 article EN Journal of Physics Conference Series 2008-07-01

OBJECTIVE: Untreated malignant large bowel obstruction is rapidly fatal. Short-term palliation of symptoms can be achieved by formation a stoma in those patients for whom resection surgery inappropriate. In the final months life, represents significant burden both and carers. Palliative endoluminal stenting may therefore an attractive alternative option this poor prognosis group. paper, we examine our experience palliative colonic stenting. PATIENTS: Twenty patients, 11 males 9 females...

10.1046/j.1463-1318.2002.00350.x article EN Colorectal Disease 2002-06-13

ABSTRACT Background Previous studies have shown that accurate process of care predicts quality care. Few examples currently exist for the acute surgical patient. A recent region wide audit had identified good outcomes patients with pancreatitis at our institution but aspects could be improved. Methods For this re-audit, a simple written pathway management those presenting was introduced in from February to July 2009. The standards were set against British Society Gastroenterology (BSG)...

10.1136/pgmj.2010.002113rep article EN Postgraduate Medical Journal 2011-04-22

Aneurysms of the femoral artery are rare in comparison to aneurysms abdominal aorta. profunda femoris exceptionally rare, accounting for less than 0.5% peripheral arterial aneurysms. These frequently associated with aneurysmal disease elsewhere. The main complications from such rupture or distal embolisation. In this report we describe treatment two true ruptured different approaches, surgical exclusion first case and minimally invasive embolisation second case.

10.1053/ejvx.2002.0153 article EN cc-by-nc-nd EJVES Extra 2002-10-01

AIMS: The aim of ipsilateral portal vein embolization is to induce hypertrophy normal tissue when resection a cancerous portion the liver contraindicated only by volume that would remain following surgery. This study reports its use in primary and metastatic tumours. METHODS: Eight patients with inoperable tumours (three women five men median age 68. 5 years; three colorectal hepatic metastases, two cholangiocarcinomas hepatocellular cancers) were selected for embolization. Selected branches...

10.1046/j.1365-2168.2000.01383-14.x article EN British journal of surgery 2000-03-01

Gallstone-related illnesses are one of the most common reasons for emergency hospital admissions, often with serious complications. Standard treatment uncomplicated gallstone-disease is by laparoscopic cholecystectomy, which can be safely and cost-effectively performed during a short stay or as day-case. This paper aims to evaluate referral pattern patients gallstones, given whether admitted could have benefited from earlier elective referral. The management these examined in context payment...

10.1108/09526861011017139 article EN International Journal of Health Care Quality Assurance 2010-02-09
Coming Soon ...