- Moyamoya disease diagnosis and treatment
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Cerebrovascular and genetic disorders
- Immunotherapy and Immune Responses
- Vascular Anomalies and Treatments
- Healthcare Systems and Technology
- Traumatic Brain Injury Research
- Organ Donation and Transplantation
- Folate and B Vitamins Research
- Patient Safety and Medication Errors
- Cell Adhesion Molecules Research
- Trypanosoma species research and implications
- Plant Disease Management Techniques
- Medical Malpractice and Liability Issues
- Connective tissue disorders research
- Dementia and Cognitive Impairment Research
- Amoebic Infections and Treatments
- Research on Leishmaniasis Studies
- Vagus Nerve Stimulation Research
- Aortic Disease and Treatment Approaches
- Esophageal and GI Pathology
Neurological Surgery
2020-2025
Northwestern University
2020-2023
Lurie Children's Hospital
2020-2022
Baylor College of Medicine
2016-2021
Texas Children's Hospital
2016-2020
Emory University
2017
Sabin Vaccine Institute
2016
The concept of the neglected tropical diseases (NTDs) is built around low socioeconomic status (SES) and poverty as most important social determinants [1].Poor health not confined to poor people, but burden disproportionately greater within communities.A combination insufficient programs, unfair economic arrangements, corrupt politics creates conditions that allow obstruct [2].Within this paradigm impact violent conflict.Conflict only facilitates relationship between health, it also a...
ABSTRACT Background Immunotherapy has revolutionized cancer treatment but yet to be translated into brain tumors. Studies in other solid tumors suggest a central role of B-cell immunity driving immune checkpoint blockade efficacy. In glioblastoma (GBM), tumor B-cells are driven regulatory state that suppresses activation and T-cell function. Methods We used spatially resolved transcriptomics multiplex immunofluorescence characterize neighborhoods within GBM identify enhanced TGFβ-signaling...
Amyloid-related imaging abnormalities (ARIA) in magnetic resonance scans have emerged as indicators of potentially serious side effects clinical trials therapeutics for Alzheimer's disease. These anomalies include an edematous type (ARIA-E) that appears hyperintense (bright) regions by T2-weighted MRI, and a characterized the deposition hemosiderin (ARIA-H) elicits hypointense signal, especially T2* susceptibility weighted images. ARIA general has been linked to presence amyloid-β (Aβ)-type...
ABSTRACT Introduction: Adapting Project Re-Engineered Discharge (Project RED), an intervention for reducing internal medicine hospital readmissions, is a promising option colorectal surgery readmissions. Methods: We conducted pilot study the adaptation and implementation of RED with patients admitted colectomy at regional VA tertiary care center between July 2014 January 2015. Implementation was evaluated using adherence to components results from Survey Healthcare Experiences Patients. The...
OBJECTIVE Genetic alterations are increasingly recognized as etiologic factors linked to the pathogenesis and development of cerebrovascular anomalies. Their identification allows for advanced screening targeted therapeutic approaches. The authors aimed describe role a collaborative approach care genetic testing in pediatric patients with neurovascular anomalies, objectives identifying what recommendations were made, yield testing, implications familial management at present future. METHODS...
Abstract BACKGROUND Safety checklists have improved surgical outcomes; however, much of the literature comes from general surgery. OBJECTIVE To identify role time-outs in neurosurgery, understand neurosurgeons’ attitudes toward time-out, and highlight areas for improvement. METHODS A cross-sectional study using a 15-item survey to evaluate how were performed across 5 hospitals affiliated with single neurosurgery training program. RESULTS Surveys sent 51 neurosurgical faculty, fellows,...
INTRODUCTION: Cerebral arteriovenous malformations (AVMs) are the most common cause of spontaneous intracranial hemorrhage in pediatric patients. Recurrence after complete surgical resection is a recognized risk that occurs primarily children. While Pediatric Neurosurgery practices traditionally focus on clinical management, recent advances have found gene mutations to play role pathogenesis and development AVMs It not known how many sporadic versus arising from familial inheritance...