Hypoglycaemic events, particularly nocturnal, affect health-related quality of life (HRQoL) via acute symptoms, altered behaviour and fear future events. We examined the respective disutility associated with a single event daytime, severe non-severe hypoglycaemia.Representative samples were taken from Canada, Germany, Sweden, United States Kingdom. Individuals completed an internet-based questionnaire designed to quantify HRQoL different diabetes- and/or hypoglycaemia-related health states....

Diabet. Med. 29, 654–661 (2012) Abstract Aims To investigate the relationship between structural and functional social support patient activation, diabetes‐related emotional distress, perceived diabetes care, self‐management behaviour HbA 1c levels among patients with Type 2 diabetes. Methods Self‐administered questionnaires were collected from 2572 After adjusting for gender, age education, Tobit logistic regression models used to examine associations network psychosocial problems,...

The aim of this study was to investigate the impact hypoglycemia according severity and time onset on health-related quality life (HRQoL) in a Canadian population.Time trade-off (TTO) methodology used estimate health utilities associated with hypoglycemic events representative sample population. A global analysis conducted United Kingdom, Canada, Germany Sweden has been published. present focuses 3 populations: general, type 1 2 diabetes. Using web-based survey, participants (>18 years)...

Objectives:To study patient preferences for diabetes-treatment related attributes among people with type 2 diabetes.Research design and methods:Participants were recruited from three diabetes out-patient clinics two general practitioner surgeries. Data collected electronically results analysed using a standard statistical model designed choice sets (conditional logit). Six characteristics relating to treatment of examined: glycated haemoglobin level (HbA1c), weight (gain or loss),...

Summary Excess weight is associated with severe outcomes of coronavirus disease 2019 (COVID‐19). We aimed to estimate the total secondary care costs by body mass index (BMI, kg/m 2 ) category when hospitalized due COVID‐19 in Europe during first wave pandemic from January June 2020. Building a health‐care cost model, this study COVID‐19. Information on risk hospitalization, admission intensive unit (ICU) and ventilation were based published data. Average per patient calculated risks ICU,...

Objectives:This study aimed to investigate the most important consequences of diabetes medication, as measured by patients' willingness pay (WTP).Research design and methods:People in Sweden were recruited using existing nationwide e-mail panels if they adults (≥18 years) with type 2 receiving pharmacological anti-diabetes treatment(s). Data collected electronically results analysed a standard statistical model designed for choice games (conditional logit). Six characteristics relating...

Peristomal skin complications (PSCs) and leakages are major issues for people living with a stoma. The purpose of this study is to understand how these stoma-linked impact health-related quality life (HRQoL) in UK population.The used time trade-off (TTO) methodology quantify health state utilities associated two stoma-related complications: PSC leakages. Respondents assessed 10 different states severity levels (no, mild, moderate or severe PSC) frequencies leakage events (2, 12 48 onto...

Purpose:People with insulin-treated diabetes often face strict regimens inflexible dose timing, frequent injections, and self-measured blood glucose (SMBG) testing. The objective of this study was to estimate the health-related quality-of-life (HRQoL) impact these aspects using time trade-off (TTO) methods.Methods:HRQoL examined via a TTO survey in UK, Canada, Sweden separate analyses 2465 respondents from general population, 274 people type 1 diabetes, 417 2 diabetes. Respondents evaluated...

The purpose of the survey was to assess knowledge family planning issues associated with disease modifying therapies (DMTs) among patients diagnosed multiple sclerosis (MS).590 Danish MS responded an online questionnaire about in MS, collecting demographics, characteristics, treatment, potential teratogenic effects DMTs, number children, occurrence unplanned pregnancies and outcome, sources information.488 females 102 males, mean age 40 years, responded. On average, it 6.5 10.9 years since...

Objective Diabetes is associated with progression to severe COVID-19. The objective of this study was estimate what extent the increased risk among people diabetes could impact secondary care costs COVID-19 throughout Europe during first wave pandemic from January June 2020.Methods Applying a health cost model based on inputs data published in international peer-reviewed journals, identified via rapid literature review aimed total sector Estimates unit were Denmark, France, Spain and UK. We...

Diabetes is associated with a number of complications, particularly if glycaemic targets are not achieved. Glycaemic control highly linked to treatment persistence and adherence. To understand the burden poor adherence, this systematic literature review identified existing evidence regarding basal insulin adherence/non-adherence persistence/non-persistence among people diabetes in Western Europe (defined as UK, France, Spain, Switzerland, Netherlands, Ireland, Austria, Portugal, Denmark,...

Objective To examine the relationship between diabetes distress and gender, association with glycemic control, social support, health behaviors, socio-economic status. Methods All adolescents, aged 15 to 18 years, in national, pediatric registry SWEDIABKIDS type 1 were invited complete an online questionnaire. A total of 2112 teenagers identified. Results 453 responses valid for analyses. Young women scored significantly higher on distress-screening instrument DDS-2. Almost half female...

There are limited data on the potential short-term benefits associated with reductions in HbA1c levels, and understanding any immediate improvements health related quality-of-life (HRQoL) through better glycaemic control may help inform diabetes management decisions. This time-trade-off (TTO) study investigated impact HRQoL three different aspects of management; change, body weight complexity treatment regimen. The was designed stages: Stage 1) Qualitative telephone interviews people type 2...

Atopic dermatitis is a chronic, inflammatory skin disease. A variety of systemic treatments are available for patients with moderate-to-severe atopic dermatitis. The efficacy, safety and administration profile these vary, determining the optimal treatment strategy may require weighing benefits drawbacks therapies diverse characteristics. This study used an online discrete choice experiment survey to investigate preferences among adults from Denmark, France, UK, or Canada. Participants were...

We investigated the association of bolus insulin dose timing with demographics, adherence, diabetes education program participation, experience hypoglycemic events, glycemic control, and patient preference among respondents type 2 diabetes.Adults from 12 countries were recruited to a Web-based self-reported survey. Adherence was measured using an adapted Morisky Medication Scale questionnaire.In total 1483 reported 58% (n = 864) dosing before meals (pre-meal cohort), 354 (24%) during or...

Summary We used the Danish National Health Registers to conduct a study on prevalence of obesity‐related comorbidities in citizens who have been diagnosed with obesity at hospital. This was retrospective observational population comprising all (≥18 years) registered specific class diagnosis Patient Register between 2002 and 2018. A total 86 980 persons hospital‐diagnosed were included population. To investigate how risk having varies degree obesity, we applied adjusted logistic regression...

Objective:The purpose of this study was to investigate the preferences people with diabetes for liraglutide vs other glucose lowering drugs, based on outcomes clinical trials.Methods:Willingness pay (WTP) drug treatment assessed by combining results from a recent WTP analysis Liraglutide Effect and Action in Diabetes (LEAD) programme. The LEAD programme included six randomised trials 3967 participants analysing efficacy safety 1.2 mg (LEAD 1–6 trials), rosiglitazone 1 trial), glimepiride 2–3...

Abstract Aims The aim of this study was to investigate associations between HbA 1c recall by patients with Type 2 diabetes and self‐management behaviours, patient activation, perception care distress. Methods In a cross‐sectional survey, 993 reported their latest . Validated scales measured Self‐reported compared Using logistic regressions, the variables interest were investigated. Results Sixty‐four per cent recalled Poor significantly associated unhealthy eating behaviour, low level...

This study assessed patient preferences, using willingness to pay as a method measure different treatment characteristics or attributes associated with injectable insulin therapy in patients type 2 diabetes. Adults diabetes 12 countries, diagnosed >6 months prior and receiving for >3 months, were recruited through representative online panel. Data collected via questionnaire analyzed standard choice model discrete experiment. A total of 3758 from North America (n=646), South (n=1537), Europe...

Abstract Purpose We aimed to estimate the total cost of bariatric surgery in Denmark. Materials and Methods The study population included all Danish citizens ≥ 18 years who had received surgery, identified National Patient Register period from 2002 2018. Patients were matched with three controls on gender, year birth, region residence. A difference-in-difference approach was used healthcare costs attributable 3 before 5 after surgery. Results Total for cases receiving during first following...

Agitation episodes are common among patients with schizophrenia or bipolar disorder. Oral and intramuscular administration methods commonly used in pharmacological treatment of acute agitation. Recently, an innovative inhalation product loxapine(Adasuve®)has become available for agitation associated disorder schizophrenia. The objective the present study was to investigate impact treatment's on health-related quality life (HRQoL) Denmark Sweden using a time trade-off (TTO) approach.The TTO...

People with allergic rhinitis (AR) who are not controlled on conventional therapy can be treated using allergy immunotherapy (AIT) administered as tablets, injections or drops. In the US, use of sublingual tablets (SLIT-tablets) is limited in comparison to subcutaneous (SCIT).This study investigated patients' preference for SLIT-tablets vs monthly weekly SCIT from a US patient perspective.We carried out discrete choice experiment (DCE) consisting two blocks eight sets. Adults and caregivers...