A5078503475- Aquaculture disease management and microbiota
- Vibrio bacteria research studies
- Bacteriophages and microbial interactions
- Physiological and biochemical adaptations
- Essential Oils and Antimicrobial Activity
- Machine Learning in Bioinformatics
- Bee Products Chemical Analysis
- Meat and Animal Product Quality
- Aquaculture Nutrition and Growth
- Microbial infections and disease research
- Genetic diversity and population structure
- Mosquito-borne diseases and control
- Biosensors and Analytical Detection
- Advanced Drug Delivery Systems
- Bacterial biofilms and quorum sensing
- Listeria monocytogenes in Food Safety
- Genetic and phenotypic traits in livestock
- Animal Genetics and Reproduction
- Aquatic life and conservation
- Lipid Membrane Structure and Behavior
- Invertebrate Immune Response Mechanisms
- Metabolomics and Mass Spectrometry Studies
- Venomous Animal Envenomation and Studies
- Fish Ecology and Management Studies
- Neurobiology and Insect Physiology Research
Southwest University
2023-2025
Xinqiao Hospital
2025
Army Medical University
2025
Chinese Academy of Fishery Sciences
2024
Ministry of Agriculture and Rural Affairs
2024
Aeromonas hydrophila is human-animal commensal bacterium that seriously threatens the development of aquaculture and human health. Type IV pili (T4P) are essential for bacterial physiological function. The relationship between molecular mechanism flpL gene affiliated to T4P pathogenicity still unclear. In research, A. with a genetically stable deletion (ΔflpL) was constructed. median lethal dose ΔflpL Crucian carp 4.87 times higher compared wild-type strain, suggesting significantly reduced...
The incidence of prostate cancer (PCa) is high among elderly men. Cepharanthine hydrochloride (CH) recognized for its important role in the prevention and treatment various diseases. However, effects mechanisms action context PCa remain unclear. Our study aims to examine therapeutic CH PCa. Targets PCa-related genes were identified using different databases, biological processes through which might exert predicted via protein-protein interaction (PPI) network enrichment analyses....
Abstract In this study, Micropterus salmoides were fed with dietary glutathione (GSH, 0, 100, 300, and 500 mg/kg) for 56 days to investigate its effects on growth performance, serum nonspecific immunity, liver antioxidant capacity, tissue morphology, intestinal microbiota. The results showed that the survival rate, weight gain specific rate condition factor increased, whereas feed conversion ratio, hepato‐somatic index, viscerosomatic index decreased in GSH groups. Compared control group,...
Aeromonas veronii is an opportunistic pathogen that poses great threat to aquaculture and human health, so there urgent need for green efficient methods deal with its infection. In this study, single gene deletion strains (AV-∆aroA, AV-∆ppk1) double strain (AV-∆aroA/ppk1) could be stably inherited were constructed. The pathogenicity test showed the median lethal doses (LD50) of AV-Δppk1, AV-ΔaroA AV-ΔaroA/ppk1 increased by 1.38-, 1.62- 6.99-fold, respectively. Biological characterization...
Aeromonas veronii is a common human and animal co-pathogenic bacterium that causes serious damage to the aquaculture industry every year. In recent years, structure of bacterial pili has been found be an important pathogenic factor. The mshK gene belongs mannose-sensitive hemagglutinin type IV pili, which vital for adhesion motility. To investigate function in A. veronii, we constructed deletion strain (ΔmshK-AV) complement (CmshK-AV) using effective suicide plasmid-mediated homologous...