A5100394354- Mesenchymal stem cell research
- Reproductive System and Pregnancy
- MicroRNA in disease regulation
- Endometriosis Research and Treatment
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Lysosomal Storage Disorders Research
- Reproductive Biology and Fertility
- Advanced MRI Techniques and Applications
- Liver physiology and pathology
- Tissue Engineering and Regenerative Medicine
- Renal and related cancers
- Neuroinflammation and Neurodegeneration Mechanisms
- Stroke Rehabilitation and Recovery
- Circular RNAs in diseases
- Wound Healing and Treatments
- Transcranial Magnetic Stimulation Studies
- Heavy Metal Exposure and Toxicity
- Pluripotent Stem Cells Research
- Aquaculture disease management and microbiota
- Extracellular vesicles in disease
- Cancer-related molecular mechanisms research
- Acupuncture Treatment Research Studies
- Ginger and Zingiberaceae research
- Barrier Structure and Function Studies
Xinxiang Medical University
2014-2025
Hubei University of Medicine
2022-2025
Zhejiang Chinese Medical University
2024
University of Missouri–Kansas City
2023-2024
Air Force Medical University
2017-2024
Handan College
2024
Zhongda Hospital Southeast University
2020-2023
National Clinical Research
2023
First Hospital of Shijiazhuang
2023
Chinese PLA General Hospital
2022
Chemotherapy was conventionally applied to kill cancer cells, but regrettably, they also induce damage normal cells with high-proliferative capacity resulting in cardiotoxicity, nephrotoxicity, peripheral nerve toxicity, and ovarian toxicity. Of these, chemotherapy-induced damages mainly include are not limited decreased reserve, infertility, atrophy. Therefore, exploring the underlying mechanism of chemotherapeutic drug-induced will pave way develop fertility-protective adjuvants for female...
Abstract Purpose WeChat-based education and care program serves as a promising nursing method for relieving mental stress in parents of pediatric patients. This study purposed to explore the influence WeChat (WECP) on health, insomnia, general state health acute lymphoblastic leukemia (ALL) Methods Totally, 146 73 primary ALL patients were randomized into WECP group (74 37 patients) standard (SC) (72 36 receive 6-month corresponding intervention. Self-rating anxiety scale (SAS), self-rating...
An eight-week feeding trial was conducted to investigate the effects of dietary andrographolide on growth performance, antioxidant capacity in liver, intestinal inflammatory response and microbiota
Metal peroxide nanomaterials as efficient hydrogen (H2O2) self-supplying agents have attracted the attention of researchers for antitumor treatment. However, relying solely on metal peroxides to provide H2O2 is undoubtedly insufficient achieve optimal effects. Herein, we construct novel hyaluronic acid (HA)-modified nanocomposites (MgO2/Pd@HA NCs) formed by decorating palladium nanoparticles (Pd NPs) onto surfaces a magnesium (MgO2) nanoflower highly effective nanoplatform tumor...
Oxidative stress is one of the main causes AMD. Hydrogen have anti-oxidative and apoptotic effects on retinal injury. However, effect hydrogen AMD not clear. In this study, fundus radiography, OCT FFA demonstrated that HRW reduced deposition drusen-like structures in RPE layer, prevented retina from thinning leakage ocular vasculature by induced NaIO3. ERG analysis confirmed effectively reversed decrease a-wave b-wave amplitude NaIO3-mice. Mechanistically, greatly oxidative reaction through...
Abstract Background Research into the pathogenesis of endometriosis (EMs) would substantially promote its effective treatment and early diagnosis. However, aetiology EMs is poorly understood controversial despite progress in research last several decades. Currently, accumulating evidence has shed light on importance endometrial stem cells (EnSCs) residing basal layer endometrium establishment progression endometriotic lesions. Therefore, we aimed to identify differences between EnSCs...
The experiment was conducted in a sealed, temperature-controlled room. initial water temperature of the treatment group 12°C, lowered by 1°C day to 8°C using chiller, and maintained at that for 3 days. then increased per 12°C heater. control were fish kept beginning experiment; T1 represents sampled on first when reached 8 from 12°C; T2 had been days; T3 12 8°C. antioxidant abilities liver, muscle, intestine large yellow croaker different temperatures times determined, expression HSP70 HSP90...
The blood–brain barrier (BBB) is an important physiological of the human body contributing to maintaining brain homeostasis and normal function. Hypoxic-ischemic (HI)-related injury one main causes neonatal acute morbidity chronic disability. previous research our group confirmed that there was serious BBB destruction during HI injury. However, at present, protection strategy very limited, further on mechanism warranted. Indole-3-propionic acid (IPA) a bacterial metabolism with...
The purpose of this study was to evaluate the potential a newly modified cyclodextrin derivative, water-soluble β-cyclodextrin-epichlorohydrin polymer (β-CDP), as an effective drug carrier enhance dissolution rate and oral bioavailability glipizide poorly model drug. Inclusion complexes with β-CDP were prepared by co-evaporation method characterized phase solubility, dissolution, differential scanning calorimetry. solubility curve classified type A(L), which indicated formation 1:1 complex...
Abstract Mesenchymal stem cells (MSCs) have been demonstrated to protect against fatty liver diseases, but the mechanism is still not clear. Menstrual blood-derived endometrial (MenSCs) are a substantial population of MSCs that can be obtained in noninvasive manner. In present study, we investigated therapeutic effects and underlying mechanisms MenSC transplantation mouse models diet-induced nonalcoholic disease (NAFLD). The results revealed MenSCs markedly promoted hepatic glycogen storage...
Pelargonic acid vanillyl amide (PAVA), a stable synthetic analog of capsaicin, exhibits potential for therapeutic applications; however, it may present cytotoxic and pro-inflammatory risks. This study aims to investigate the injury effects PAVA on cocultured skin cell model in vitro. Human keratinocytes dermal fibroblasts were co-cultured exposed at concentrations ranging from 12.5 200 µM durations 5, 24, 48 h. Cell proliferation was quantified using MTS assays. Morphological changes...
The relationship between personal hygiene and the risk of communicable diseases is well established, with socioeconomic status recognized as a significant factor in this context. Given that infectious diseases, environmental pollutants, metals share pathways entry into human body, study sought to investigate correlation practices urinary metal levels preschool-aged children. A cross-sectional analysis involving 1,477 preschoolers was conducted where concentrations 23 were determined using...