- Plant-Microbe Interactions and Immunity
- Plant nutrient uptake and metabolism
- Plant Pathogenic Bacteria Studies
- Microbial Metabolic Engineering and Bioproduction
- Listeria monocytogenes in Food Safety
- Probiotics and Fermented Foods
- Erythrocyte Function and Pathophysiology
- Biofuel production and bioconversion
- Photosynthetic Processes and Mechanisms
- Plant Stress Responses and Tolerance
- Mitochondrial Function and Pathology
- Legume Nitrogen Fixing Symbiosis
- Plant Molecular Biology Research
- Sustainability and Ecological Systems Analysis
- Microbial Fuel Cells and Bioremediation
University of Oxford
2014-2023
Stomatins belong to the band-7 protein family, a diverse group of conserved eukaryotic and prokaryotic membrane proteins involved in formation large complexes as protein-lipid scaffolds. The Arabidopsis (Arabidopsis thaliana) genome contains two paralogous genes encoding stomatin-like (SLPs; AtSLP1 AtSLP2) that are phylogenetically related human SLP2, mitochondrial fusion complex inner membrane. We used reverse genetics combination with biochemical methods investigate function AtSLPs....
While flux balance analysis (FBA) provides a framework for predicting steady-state leaf metabolic network fluxes, it does not readily capture the response to environmental variables without being coupled other modelling formulations. To address this, we an FBA model of 903 reactions soybean (Glycine max) metabolism with e-photosynthesis, dynamic that captures kinetics 126 photosynthesis and associated chloroplast carbon metabolism. Successful coupling was achieved in iterative formulation...
Nitrogen-fixing symbioses allow legumes to thrive in nitrogen-poor soils at the cost of diverting some photoassimilate their microsymbionts. Effort is being made bioengineer nitrogen fixation into nonleguminous crops. This requires a quantitative understanding its energetic costs and links between metabolic variations symbiotic efficiency. A whole-plant model for soybean (Glycine max) with associated microsymbiont Bradyrhizobium diazoefficiens was developed applied predict cost-benefit...
The aromatic amino acid tryptophan is the main precursor for indole-3-acetic (IAA), which involves various parallel routes in plants, with indole-3-acetaldoxime (IAOx) being one of most common intermediates. Auxin signaling well known to interact free radical nitric oxide (NO) perform a more complex effect, including regulation root organogenesis and nitrogen nutrition. To fathom link between IAA NO, we use metabolomic approach analyze contents low-molecular-mass molecules cultured cells...
Contaminated fresh produce has been routinely linked to outbreaks of Salmonellosis. Multiple studies have identified Salmonella enterica factors associated with successful colonization diverse plant niches and tissues. It also well documented that S. can benefit from the conditions generated during disease by host-compatible pathogens. In this study, we compared capacity two common research strains, 14028s LT2 (strain DM10000) opportunistically colonize leaf apoplast model hosts Arabidopsis...
Abstract With an increase in foodborne illnesses associated with the consumption of fresh produce, it is important to understand interactions between human bacterial enteric pathogens and plants. It was previously established that diseased plants can create a permissive environment for opportunistic endophytic colonization pathogens. However, factors contribute during plant disease are largely unknown. Here, we show both strain host significantly increased populations when co-inoculated...