Pauline Conigliaro

ORCID: 0000-0003-0898-7324
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About
Contact & Profiles
Research Areas
  • Enzyme-mediated dye degradation
  • Electrochemical sensors and biosensors
  • bioluminescence and chemiluminescence research
  • Dye analysis and toxicity
  • Plant chemical constituents analysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Beetle Biology and Toxicology Studies
  • Phytochemical compounds biological activities
  • Protein Interaction Studies and Fluorescence Analysis

Università degli Studi della Tuscia
2022-2023

Current therapy against melanoma relies on surgical treatment or, in alternative, conventional drug therapy. Often these therapeutic agents are ineffective due to the development of resistance phenomena. For this purpose, chemical hybridization emerged as an effective strategy overcome resistance. In study, a series molecular hybrids were synthesized combining sesquiterpene artesunic acid with panel phytochemical coumarins. Cytotoxicity, antimelanoma effect, and cancer selectivity novel...

10.1021/acsmedchemlett.3c00019 article EN ACS Medicinal Chemistry Letters 2023-04-24

Surface-Enhanced Raman Spectroscopy (SERS) is a specialized spectroscopic technique based on the enhancement of scattering signals molecules adsorbed or in close proximity to certain rough nanostructured metal surfaces. It's an extremely sensitive and powerful analytical tool for investigation biological molecules, revolutionizing field bioanalytical chemistry. The signal due various effects, most important thought be interaction between electromagnetic wave associated with laser used...

10.3390/ecsa-10-16164 article EN cc-by 2023-11-15

Laccase is an enzyme belonging to the oxidoreductase class and has copper atoms in catalytic centre. The property of this consists enzymatic oxidation phenolic compounds, corresponding quinones, with concomitant reduction molecular oxygen water. There growing interest developing innovative sensing methods for detecting substrates, such as catechol. Preliminary absorption fluorescence measurements were carried out UV-visible range evaluate possibility using variations produced spectra laccase...

10.3390/ecsa-9-13333 article EN cc-by 2022-11-01
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