- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- DNA and Nucleic Acid Chemistry
- Salivary Gland Disorders and Functions
- Surgical Simulation and Training
- Growth Hormone and Insulin-like Growth Factors
- Molecular Junctions and Nanostructures
- Soft Robotics and Applications
- Acupuncture Treatment Research Studies
- Diabetes and associated disorders
- Anatomy and Medical Technology
- Dermatology and Skin Diseases
- Advanced Biosensing Techniques and Applications
China Academy of Chinese Medical Sciences
2024
Guang’anmen Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Beijing Normal University
2018-2020
University of Illinois Urbana-Champaign
2019
Zhejiang University
2019
The complete formation of stem-loop (i.e., hairpin) configuration on chip surface is particular importance for the application hairpin DNA (hpDNA) in building biosensors various analytes with optimized performance. We report herein a convenient electrochemical protocol evaluating yield conformations upon self-assembly electrode surface. As different hydrolysis capability Exonuclease I (Exo I) toward single-stranded (ssDNA) and hpDNA, we can selectively remove ssDNA from but retain hpDNA...
An aptamer-truncating strategy was utilized to create high-performance GO-based aptasensors for detection of multiple mycotoxins.
The aim of the study was to observe effect acupuncture on regulating interleukin (IL)-17, tumor necrosis factor (TNF)-ɑ, and aquaporins (AQPs) in Sjögren's syndrome (SS) patients non-obese diabetic (NOD) models.Levels anti-AQP 1, 5, 8, 9 antibodies, IL-17, TNF-ɑ serum SS were compared prior following 20 treatment visits during 8 weeks. While murine model, five groups divided receive interventions for 4 weeks, including control, acupuncture, isoflurane, hydroxychloroquine. submaxillofacial...
<title>Abstract</title> <bold>Background</bold> Abnormal activation of the interferon (IFN) signalling plays a central role in progression Sjögren’s syndrome (SS). However, causal relationship between IFN and SS remains unclear, with complex interactions existing among genetic variants, epigenetic modifications, inflammatory cytokine levels, expression IFN-associated genes. Thus, order to reveal potential causality interaction mechanisms gene expression, DNA methylation, cytokines, SS, our...
Quantitative comparison of three representative staining methods for developing multichannel colorimetric biochips, which allow visual detection multiple cancer markers.
We report a versatile fluorometric <italic>in-situ</italic> hybridization protocol for quantifying hairpin conformations in DNA self-assembled monolayers on substrates, which facilitates the creation of hpDNA-based biosensors with optimal detection performance.