Nader Afshar

ORCID: 0000-0003-0903-8008
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About
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Research Areas
  • Advanced X-ray Imaging Techniques
  • Medical Imaging Techniques and Applications
  • X-ray Spectroscopy and Fluorescence Analysis
  • Advanced X-ray and CT Imaging
  • Advanced Radiotherapy Techniques
  • Radiation Therapy and Dosimetry
  • Plant Micronutrient Interactions and Effects
  • Aluminum toxicity and tolerance in plants and animals
  • Virus-based gene therapy research
  • Palliative Care and End-of-Life Issues
  • Geotechnical and Geomechanical Engineering
  • Geotechnical Engineering and Underground Structures
  • Heavy Metals in Plants
  • Artificial Intelligence in Healthcare
  • Cancer survivorship and care
  • Advanced Electron Microscopy Techniques and Applications
  • Astrophysical Phenomena and Observations
  • Ultrasonics and Acoustic Wave Propagation
  • Autonomous Vehicle Technology and Safety
  • Plant Stress Responses and Tolerance
  • Electron and X-Ray Spectroscopy Techniques
  • Traffic and Road Safety
  • Traffic control and management
  • Patient-Provider Communication in Healthcare

Australian Nuclear Science and Technology Organisation
2017-2025

Australian Synchrotron
2016-2025

Kharazmi University
2024

The X-ray fluorescence microscopy (XFM) beamline is an in-vacuum undulator-based (XRF) microprobe at the 3 GeV Australian Synchrotron. delivers hard X-rays in 4–27 keV energy range, permitting K emission to Cd and L M for all other heavier elements. With a practical low-energy detection cut-off of approximately 1.5 keV, low- Z constrained Si, with Al detectable under favourable circumstances. has two scanning stations: Kirkpatrick–Baez mirror microprobe, which produces focal spot 2 µm ×...

10.1107/s1600577520010152 article EN Journal of Synchrotron Radiation 2020-08-19

A decade ago, prototypes of the Maia detector successfully demonstrated a fresh approach to X-ray fluorescence microscopy (XFM) imaging that combined massively parallel architecture with dedicated pulse shaping and capture on each channel, asynchronous acquisition X-rays as an event stream, real-time processing data [1, 2]. Today, number XFM beamlines raster scan sample through focused beam construct images element concentration chemical state use 384-detector array version for...

10.1080/08940886.2018.1528430 article EN Synchrotron Radiation News 2018-11-02

The first new beamline of the BRIGHT project—involving construction eight beamlines at Australian Synchrotron—is Micro-Computed Tomography (MCT) beamline. MCT will extend facility’s capability for higher spatial resolution X-ray-computed tomographic imaging allowing commensurately smaller samples in comparison with existing Imaging and Medical Beamline (IMBL). source is a bending-magnet it operating X-ray energy range from 8 to 40 keV. provides important biological material-science...

10.3390/app13031317 article EN cc-by Applied Sciences 2023-01-18

Scanning X-ray fluorescence tomography was once considered impractical due to prohibitive measurement time requirements but is now common for investigating metal distributions within small systems.A recent look-ahead the possibilities of 4 th -generation synchrotron light sources [J.Synchrotron.Radiat.21, 1031(2014)] raised possibility a spiral-scanning scheme where motion overheads are almost completely eliminated.Here we demonstrate spiral scanning and use Fourier ring correlation analysis...

10.1364/oe.25.023424 article EN cc-by Optics Express 2017-09-15

Abstract Background In clinical radiotherapy, the patient remains static during treatment and only source is dynamically manipulated. synchrotron beam fixed, horizontally wide vertically small, requiring to be moved through ensure full target coverage, while shaping field conform target. No system exists that performs both dynamic motion of beam. Purpose We developed tested a new delivery capable delivering conformal fields with robotic positioning for use on Imaging Medical Beamline (IMBL)...

10.1002/mp.17750 article EN cc-by Medical Physics 2025-03-16

Owing to its extreme sensitivity, quantitative mapping of elemental distributions via X-ray fluorescence microscopy (XFM) has become a key microanalytical technique. The recent realisation scanning diffraction (SXDM) meanwhile provides an avenue for super-resolved ultra-structural visualization. similarity their experimental geometries indicates excellent prospects simultaneous acquisition. Here, in both step- and fly-scanning modes, robust, XFM-SXDM is demonstrated.

10.1107/s1600577516011917 article EN Journal of Synchrotron Radiation 2016-08-11

Over the last decade ptychography has progressed rapidly from a specialist ultramicroscopy technique into mature method accessible to non-expert users. However, improve scientific value data must reconstruct reliably, with high image quality and at no cost other correlative methods. Presented here is implementation of high-speed used Australian Synchrotron on XFM beamline, which includes free-run collection mode where dead time eliminated scan optimized. It shown that viable for fast...

10.1107/s1600577521012856 article EN cc-by Journal of Synchrotron Radiation 2022-01-17

Synchrotron-based X-ray fluorescence microscopy (XFM) analysis is a powerful technique that can be used to visualize elemental distributions across broad range of sample types. Compared conventional mapping techniques such as laser ablation inductively coupled plasma mass spectrometry or benchtop XFM, synchrotron-based XFM provides faster and more sensitive analyses. However, access synchrotron beamlines highly competitive, result, these are often oversubscribed. Therefore, experiments...

10.1021/acs.analchem.1c04255 article EN cc-by Analytical Chemistry 2022-03-11

Abstract Background Novel synchrotron radiotherapy techniques are currently limited to using prefabricated beam‐limiting blocks for field definition. For large experiments, a single square tungsten block is often used every treatment since conformal both patient and specific, require long lead times fabrication. Future treatments would benefit from dynamic collimator system. Purpose We developed tested novel design use on the Imaging Medical Beamline (IMBL) at ANSTO Australian Synchrotron....

10.1002/mp.16664 article EN cc-by-nc Medical Physics 2023-08-02

Research utilizing synchrotron radiation for radiotherapy applications is becoming increasingly complex as it pushes towards canine clinical trials [1]–[3]. Recently, several beamline developments at the Imaging and Medical Beamline (IMBL) have taken place supporting forthcoming trials. A high speed dynamic collimator has been developed tested on IMBL shaping beam a target moved through beam. 6-Axis Kuka robot also configured to allow be positioned treated with respect In this work, we...

10.1109/nssmicrtsd49126.2023.10337890 article EN 2023-11-04

The aim of this study was to evaluate the self-reported wishes cancer and dialysis patients (3-19 years) examine its possible association with patients' demographics clinical characteristics. This is a cross- sectional included undergoing chemotherapy renal failure that were dialyzing during period 6 months. From total 46 participated in study, majority are younger (<6 than chronic (52% vs 13 %, p=0.01). Cancer patients’ wish buy staves 4 times more comparison other group. current provides...

10.15412/j.jbtw.01060603 article EN Journal of Biology and Today s World 2017-01-01

Summary Knowledge of elemental distribution and concentration within plant tissues is crucial in the understanding almost every process that occurs plants. However, analytical limitations have hindered microscopic determination changes over time location nutrients contaminants living tissues. We developed a novel method using synchrotron-based micro X-ray fluorescence (μ-XRF) allows for laterally-resolved, multi-element, kinetic analyses leaf vivo . To test utility this approach, we examined...

10.1101/228577 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2017-12-04

Background: People with diabetes in general have a higher risk of developing Chronic Kidney Disease (CKD). The early detection CKD people helps their health care providers to adjust therapy slow down the disease progression stages, prevent complications, and reduce cardiovascular-related conditions. It also takes great financial burden off insurance companies long run by way future treatment costs. We developed model that uses historical data from past 2 years (PwD) predicts chance them...

10.2337/db21-15-lb article EN Diabetes 2021-06-01
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