A5090133360- Cancer Genomics and Diagnostics
- Genetics, Bioinformatics, and Biomedical Research
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Renal and Vascular Pathologies
- Artificial Intelligence in Healthcare
- BRCA gene mutations in cancer
- Global Cancer Incidence and Screening
- Blood donation and transfusion practices
- Maternal Mental Health During Pregnancy and Postpartum
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- SARS-CoV-2 detection and testing
- Organ Transplantation Techniques and Outcomes
- Anesthesia and Sedative Agents
- Global Maternal and Child Health
- Respiratory Support and Mechanisms
- Healthcare professionals’ stress and burnout
- Cutaneous Melanoma Detection and Management
- Injury Epidemiology and Prevention
- Hedgehog Signaling Pathway Studies
- Parasitic Infections and Diagnostics
- Burn Injury Management and Outcomes
- Global Health and Surgery
- Child and Adolescent Psychosocial and Emotional Development
St. Paul's Hospital Millennium Medical College
2016-2025
University of KwaZulu-Natal
2024
Bahir Dar University
2024
Google (United States)
2021
Women of sub-Saharan African descent have disproportionately higher incidence triple-negative breast cancer (TNBC) and TNBC-specific mortality across all populations. Population studies show racial differences in TNBC biology, including prevalence basal-like quadruple-negative subtypes Americans (AA). However, previous investigations relied on self-reported race (SRR) primarily U.S. Due to heterogeneous genetic admixture biological consequences social determinants, the true association...
Renal transplantation is a critical treatment for end-stage renal disease, but graft failure remains significant concern. Accurate prediction of survival crucial to identify high-risk patients. This study aimed develop prognostic models predicting and compare the performance statistical machine learning models. The utilized data from 278 transplant recipients at Ethiopian National Kidney Transplantation Center between September 2015 February 2022. To address class imbalance data, SMOTE...
The prevalence of end-stage renal disease has raised the need for replacement therapy over recent decades. Even though a kidney transplant offers an improved quality life and lower cost care than dialysis, graft failure is possible after transplantation. Hence, this study aimed to predict risk among post-transplant recipients in Ethiopia using selected machine learning prediction models.The data was extracted from retrospective cohort at Ethiopian National Kidney Transplantation Center...
Wastewater surveillance systems have become an important component of COVID-19 outbreak monitoring in high-income settings. However, its use most low-income settings has not been well-studied. This study assessed the feasibility and utility wastewater system to monitor SARS-CoV-2 RNA Addis Ababa, Ethiopia. The was conducted at nine Membrane Bio-reactor (MBR) processing plants. samples were collected two separate time series. known leftover RT-PCR tested nasopharyngeal swabs processed using...
Abstract Background Emergence agitation is a transient confusional state of child associated with consciousness from general anaesthesia, commonly occurs in the postoperative setting which delays their recovery and exposes them to traumas. The main objective current study was investigate magnitude emergence agitation, its interventions factors among paediatric surgical patients at Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia. Methods based cross-sectional...
The aim of this study was to assess the health-related quality life patients with T2DM and hypertension attending public health facilities in Addis Ababa, Ethiopia.A cross-sectional conducted from 1st through 30th August 2020 at selected institutions. Health were chosen purposively based on patient load. Participants drawn after proportional size allocation. A translated EQ-5D-3L, EQ-VAS instrument used collect data. Analysis done using SPSS v.26.0. Both parametric non-parametric models...
Abstract Background the rapid spread of COVID-19, its lethality in severe cases and absence specific medicine poses a huge threat to human life health, as well impact on mental health. Facing this critical situation, health care workers front line who are directly involved diagnosis, treatment, patients with COVID-19 at risk developing psychological distress other symptoms including emotional disturbance. Objective aim study will be assess current state responses perceived stressors...
Purpose: This study aimed at looking into the demand and utilization of blood components a tertiary teaching hospital in Ethiopia. Methods: A cross-sectional was conducted from June 1, 2018 to August 31, St Paul's Hospital Millennium Medical College. Data on types products requested, indication for transfusion, availability different components, were collected by structured questionnaire. entered SPSS version 20.1 presented as frequency percentage. Results: Blood requested 819 patients...
<title>Abstract</title> Introduction: Renal transplantation is a critical treatment that can save the lives of individuals who are suffering from end-stage renal disease (ESRD), but graft failure remains significant concern. Accurate prediction survival after crucial as it enables clinicians to identify patients at higher risk failure. This study aimed develop clinical prognostic models for predicting and compare performance various statistical machine learning models. Methodology: The...
Background: Cecal volvulus is a rare cause of adult intestinal obstruction occurring 2.8– 7.1 persons per million year. Its rarity and the variety clinical symptoms may lead to delay in diagnosis appropriate intervention. Case Presentation: Here, we present 25-year old female patient from rural area who presented with 3-day history colicky abdominal pain vomiting bilious content; she had also developed distension, failed pass feces, flatus. She underwent emergency laparotomy, where...
Purpose: Renal vascular anatomy is known for presenting a wide range of variations.Kidneys with variant renal anatomy, when used as graft, appear to have potential risk that could impair the outcome kidney transplantation.Information on variation and its implication in surgical transplantation has not been well studied.The present study was aimed at evaluating allografts vasculature compared without national center Ethiopia.Patients Methods: A health institution-based retrospective cohort...
Background. Globally, injury continues to be an important cause of morbidity and mortality both in developed developing countries. Abdominal injuries are among the major causes trauma admissions. This study aimed assess patterns abdominal at AaBET St. Paul’s Hospital Millennium Medical College. Methods. A cross-sectional was done on all adult patients who sustained presented emergency department managed College over a two-year period from January 2018 December 2019. Results. total 165...
Background: Transplantation in economically disadvantaged region does not meet the needs of populace. Training specialists low income countries rather than sending fellows abroad for training may offer sustainable capacity building. Objectives: To document kidney transplantation progress terms trainee’s individual and team performance to determine how many transplants are necessary train an experienced surgeon with no transplant experience. Methods: Data collected from only center country....
Gastrointestinal tract malignant melanoma is an uncommon form of neoplasm that may be either primary or metastatic. Diagnosis often delayed until the illness becomes emergency due to complications, such as intestinal hemorrhage, obstruction and perforation. We report a case 42 year-old Ethiopian male patient presented department with sign symptoms obstruction. The underwent laparotomy, ileo-ileal intussusception reduced small bowel mass resection done. histopathologic examination confirmed...
Hydatid cyst is one form of parasitic infestation caused by the larval stage a cestode species called Echinococcus . The omentum rarest sites for harboring hydatid cyst. We are reporting in 14 year-old Ethiopian patient. Due to its rareness, information about appearances cysts within inadequate. believe that this case report will help augment knowledge describing and discussing clinical radiological findings.
Abstract Background : Burn is a very devastating form of trauma, which responsible for significant percentage morbidities and mortalities caused by injury accidents worldwide. Thermal destroys the skin barrier that normally prevents invasion microorganisms makes burn wounds susceptible site colonization endogenous exogenous origin. Methods: A prospective cross-sectional study was held at Addis Ababa Burn, Emergency Trauma (AaBET) Hospital, Ababa, Ethiopia, from December 01, 2020 to November...
<div>Abstract<p>Women of sub-Saharan African descent have disproportionately higher incidence triple-negative breast cancer (TNBC) and TNBC-specific mortality across all populations. Population studies show racial differences in TNBC biology, including prevalence basal-like quadruple-negative subtypes Americans (AA). However, previous investigations relied on self-reported race (SRR) primarily U.S. Due to heterogeneous genetic admixture biological consequences social...
Supplementary Data from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome Women of Descent
Supplementary Figure from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome Women of Descent
Supplementary Figure from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome Women of Descent