- Obsessive-Compulsive Spectrum Disorders
- Autism Spectrum Disorder Research
- Epilepsy research and treatment
- Eating Disorders and Behaviors
- Pharmacological Effects and Toxicity Studies
- Psychosomatic Disorders and Their Treatments
- Neurological disorders and treatments
- EEG and Brain-Computer Interfaces
- Mental Health and Psychiatry
- Functional Brain Connectivity Studies
- Neurology and Historical Studies
- Attention Deficit Hyperactivity Disorder
- Body Image and Dysmorphia Studies
- Parkinson's Disease Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Bipolar Disorder and Treatment
- Neural dynamics and brain function
- Botulinum Toxin and Related Neurological Disorders
- Genetic Neurodegenerative Diseases
- Behavioral and Psychological Studies
- Schizophrenia research and treatment
- Memory and Neural Mechanisms
- Philosophy and Theoretical Science
- Neurological and metabolic disorders
University of Birmingham
2016-2025
University College London
2016-2025
Aston University
2016-2025
Centre for Mental Health
2015-2025
Birmingham and Solihull Mental Health NHS Foundation Trust
2014-2025
University of Milano-Bicocca
2022-2025
Azienda Ospedaliera San Gerardo
2024-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2024-2025
Sobell House
2014-2024
National Health Service
2012-2023
Effective treatment of epilepsy depends on medication compliance across a lifetime, and studies indicate that drug tolerability is significant limiting factor in maintenance. Available antiepileptic drugs (AEDs) have the potential to exert detrimental effects cognitive function therefore compromise patient wellbeing. On other hand, some agents may serve enhance function. In this review paper, we highlight range cognition linked variety newer older AEDs, encompassing key alterations both...
Tourette Syndrome (TS) is more than having motor and vocal tics, this review will examine the varied co-morbidities as well social impact Quality of Life (QoL) in individuals with TS. The relationship between any individual his/her environment complex further exaggerated case a person For example, tics may play significant role shaping person's experiences, perceptions interactions environment. Further, associated clinical features, co-existing psychopathologies compound or alter...
Gilles de la Tourette syndrome (GTS) is a chronic neuropsychiatric disorder which has significant detrimental impact on the health-related quality of life (HR-QOL) patients. However, no patient-reported HR-QOL measures have been developed for this population.The development and validation new scale quantitative assessment in patients with GTS.In stage 1 (item generation), pool 40 potential items was generated based interviews 133 GTS outpatients, literature review, consultation experts. In 2...
<b>Background:</b> Eighteen patients with severe and refractory Tourette syndrome (TS) underwent bilateral thalamic deep brain stimulation (DBS). <b>Objective:</b> To assess the long-term outcome on tics, behavioral symptoms, cognitive functions in largest case series of DBS for TS to date. <b>Methods:</b> In this prospective cohort study, 15 original 18 were evaluated before after surgery according a standardized protocol that included both neuropsychiatric neuropsychological assessments....
Summary Purpose: Different authors suggested the occurrence of a pleomorphic affective syndrome in patients with epilepsy named interictal dysphoric disorder (IDD). We sought to investigate whether IDD occurs only and validate features against DSM‐IV criteria. Methods: Consecutive diagnosis (E) or migraine (M) have been assessed using BDI, MDQ, Interictal Dysphoric Disorder Inventory (IDDI), questionnaire specifically created evaluate symptoms. Diagnosis current lifetime Axis I disorders was...
Tourette syndrome (TS) is a chronic neurodevelopmental disorder characterized by tics: repetitive, involuntary movements and vocalizations. These symptoms can have significant impact on patients’ daily functioning across many domains. Tics tend to be most severe in child adolescent sufferers, so their presence has the potential period of life that both critical for learning often associated with experience greater social tension self-consciousness than adulthood. Furthermore, control over...
Tourette syndrome is a childhood-onset neuropsychiatric disorder with high prevalence of attention deficit hyperactivity and obsessive-compulsive co-morbidities. Structural changes have been found in frontal cortex striatum children adolescents. A limited number morphometric studies persisting into adulthood suggest ongoing structural alterations affecting frontostriatal circuits. Using cortical thickness estimation voxel-based analysis T1- diffusion-weighted magnetic resonance images, we...
As different areas within the PMC have connectivity patterns with various cortical and subcortical regions, we hypothesized that distinct functional modules may be present PMC. Because appears to most active region during resting state, it has been postulated play a fundamental role in control of baseline brain functioning default mode network (DMN). Therefore one goal this study was explore which components are specifically involved DMN. In sample seventeen healthy volunteers, performed an...