A5036279579- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Synthesis and biological activity
- Cancer-related gene regulation
- Ferroptosis and cancer prognosis
- Pulmonary Hypertension Research and Treatments
- Circular RNAs in diseases
- Histone Deacetylase Inhibitors Research
- Vascular Anomalies and Treatments
- Gynecological conditions and treatments
- Cancer Mechanisms and Therapy
- Female Genital Mutilation/Cutting Issues
- Tracheal and airway disorders
Cangzhou Central Hospital
2023-2024
Second Hospital of Hebei Medical University
2022-2023
Hebei Medical University
2022-2023
Background: Ferroptosis, a form of non-apoptotic cell death, has aroused worldwide interest in cancer researchers. However, the current study about correlation between ferroptosis-related genes (FRGs) and endometrial (EC) remains limited. Methods: First, transcriptome profiling clinical data EC patients were downloaded from The Cancer Genome Atlas (TCGA) Clinical Proteomic Tumor Analysis Consortium (CPTAC) program as training group testing group, respectively. FRGs acquired through...
Distinguished from cuproptosis and ferroptosis, disulfidptosis has been described as a newly discovered form of non-programmed cell death tightly associated with glucose metabolism. However, the prognostic profile disulfidptosis-related lncRNAs (DRLRs) in ovarian cancer (OC) their biological mechanisms need to be further elucidated.
5-Methylcytosine (m5C) RNA modification is closely implicated in the occurrence of a variety cancers. Here, we established novel prognostic signature for ovarian cancer (OC) patients based on m5C modification-related genes and explored correlation between these with tumor immune microenvironment.Methylated-RNA immunoprecipitation sequencing helped us to identify candidate related at first. Based TCGA database, screened differentially expressed prognosis constructed model using LASSO Cox...
Combining network pharmacology with molecular docking, our study revealed the candidate targets and mechanisms of Shu Yu Wan (SYW) for treating cervical cancer (CC). The associated CC active compounds in SYW were identified through TCGA, GeneCards TCMSP databases. Consequently, a total 16 38 common related to predicted. Genes TP53 CDK2 are among hub genes PPI network. results GO KEGG enrichment analyses suggested that exerted pharmacological effects on by regulating cellular senescence, p53...